Encyclopedia of Cancer

2011 Edition
| Editors: Manfred Schwab

Fibroblast Growth Factor 2

Reference work entry
DOI: https://doi.org/10.1007/978-3-642-16483-5_2174

Definition

Synonym FGF2 basic FGF; is a broad spectrum and pleiotropic mitogen for growth and differentiation, affecting epithelial and endothelial cells, smooth muscle cells, and osteoblasts. FGF2 incites tumor angiogenesis, is expressed by various tumor cell lines, and seems to be biologically important in tumor progression and metastasis.

 Fibroblast Growth Factors

Copyright information

© Springer-Verlag Berlin Heidelberg 2011