Encyclopedia of Cancer

2011 Edition
| Editors: Manfred Schwab

FGD1

Reference work entry
DOI: https://doi.org/10.1007/978-3-642-16483-5_2164

Definition

Faciogenital dysplasia 1 was the first identified gene product responsible for this disease. It functions as an activator for the small GTPase Cdc42, which in turn serves to activate N-WASp and other actin-related events.

 Cortactin

Copyright information

© Springer-Verlag Berlin Heidelberg 2011