Encyclopedia of Cancer

2011 Edition
| Editors: Manfred Schwab

Accelerated Phase

Reference work entry
DOI: https://doi.org/10.1007/978-3-642-16483-5_19

Definition

Occurs between chronic phase and  blast crisis. Characterized by 10–19% myeloblasts and >20% basophils in blood or bone marrow and cytogenetic evolution; also increasing splenomegaly, platelet count, or white blood cells if unresponsive to treatment.

 Nilotinib

Copyright information

© Springer-Verlag Berlin Heidelberg 2011