Encyclopedia of Cancer

2011 Edition
| Editors: Manfred Schwab


  • Anas YounesEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-642-16483-5_18


Doxorubicin, bleomycin, vinblastine, and dacarbazine combination chemotherapy used for the treatment of patients with Hodgkin lymphoma.


ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) is the most widely used regimen for the treatment of early and advanced stage Hodgkin lymphoma (HL). Treatment of patients with early stage classical HL evolved over the last three decades. Radiation therapy alone as the single treatment modality is no longer practiced. Today, the most widely used approach is combined modality therapy (chemotherapy plus involved field radiation therapy). In general, two (for favorable early stage) to four (for unfavorable early stage) cycles of ABVD plus 30 Gy of involved field radiation therapy is the most widely used standard of care approach. Using this approach, more than 90% of the patients are expected to be cured of their disease. Patients with bulky stage II disease, (especially with bulky mediastinal mass), or stage II with...

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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  1. 1.Department of Lymphoma and MyelomaM.D. Anderson Cancer CenterHoustonUSA