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Common Fragile Sites

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Specific chromosomal loci that are especially prone to forming gaps and break as seen on metaphase chromosomes under conditions of replication stress. Found in all individuals, common fragile sites are considered a normal component of human chromosomes.

Fragile Sites

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© 2011 Springer-Verlag Berlin Heidelberg

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(2011). Common Fragile Sites. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16483-5_1278

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