The predilution mode consists in the infusion of the replacement fluid in the arterial line (prefilter) during hemofiltration or hemodiafiltration therapy. The predilution mode decreases the risk of filter clotting and allows a greater ultrafiltration rate, increasing the convective clearance. However, the diffusive clearance is reduced in hemodiafiltration, due to dilution of the solutes. (See Postdilution.)
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© 2012 Springer-Verlag Berlin Heidelberg
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(2012). Predilution. In: Vincent, JL., Hall, J.B. (eds) Encyclopedia of Intensive Care Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00418-6_3262
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DOI: https://doi.org/10.1007/978-3-642-00418-6_3262
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