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Membrane Disrupting Proteins

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Abstract:

Membrane damaging proteins, found widely in biology, are extensively used by microorganisms to cause disease in hosts or attack competing organisms. The proteins must travel to their target in a water soluble state and then insert into the membrane phase. This chapter deals with the fundamental features of such proteins, highlighting the importance of secondary structure formation during membrane insertion and the role of tryptophan residues in interfacial binding.

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Lakey, J.H., Anderluh, G. (2010). Membrane Disrupting Proteins. In: Timmis, K.N. (eds) Handbook of Hydrocarbon and Lipid Microbiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77587-4_30

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