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Crescentic Glomerulonephritis

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Pediatric Nephrology

Abstract

Crescentic glomerulonephritis (GN) is a rare condition in children, clinically characterized by features of rapidly progressive GN (RPGN) with rapid loss of renal function. Renal histology shows extracapillary proliferation in the Bowman’s space resulting in formation of crescents in most glomeruli. These crescents are formed when breaks in glomerular capillaries allow leakage of cells and plasma proteins into Bowman’s space, as might occur in almost any glomerulonephritis, and sometimes in diseases that do not primarily affect the glomeruli.

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Author information

Authors and Affiliations

  1. Division of Nephrology, All India Institute of Medical Sciences, New Delhi, India

    Arvind Bagga

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  1. Arvind Bagga
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Editors and Affiliations

  1. Medical College of Wisconsin, Wisconsin, USA

    Ellis Avner (Director, Children's Research Institute, CHHS, Associate Dean for Research, Professor of Pediatrics and Physiology) (Director, Children's Research Institute, CHHS, Associate Dean for Research, Professor of Pediatrics and Physiology)

  2. Harvard Medical School, Children's Hospital Boston, 300 Longwood Avenue, Boston, Massachusetts, 02115, USA

    William Harmon (Professor of Pediatrics, Director, Pediatric Nephrology) (Professor of Pediatrics, Director, Pediatric Nephrology)

  3. Service de Néphrologie Pédiatrique Centre de référence des Maladies Rénales Héréditaires de l'Enfant et de l'Adulte (MARHEA), Hôpital Necker‐Enfants Malades, 149, rue de Sèvres, 75743, Paris Cedex 15, France

    Patrick Niaudet

  4. Department of Pediatrics Wakayama Medical University, Wakayama Medical University Hospital, 641–8510811–1, Kimiidera, Wakayama City, Japan

    Norishige Yoshikawa (Professor and Chair Pediatrician‐in‐Chief) (Professor and Chair Pediatrician‐in‐Chief)

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© 2009 Springer-Verlag Berlin Heidelberg

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Bagga, A. (2009). Crescentic Glomerulonephritis. In: Avner, E., Harmon, W., Niaudet, P., Yoshikawa, N. (eds) Pediatric Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76341-3_34

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  • DOI: https://doi.org/10.1007/978-3-540-76341-3_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-76327-7

  • Online ISBN: 978-3-540-76341-3

  • eBook Packages: MedicineReference Module Medicine

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