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Definition

Acute tolerance is a diminution of effect either during a single drug-taking episode such that the drug produces greater effects as blood concentration increases compared to when blood concentration decreases, or if the effect is less on the second time that the drug is taken.

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© 2010 Springer-Verlag Berlin Heidelberg

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Foltin, R.W. (2010). Acute Tolerance. In: Stolerman, I.P. (eds) Encyclopedia of Psychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68706-1_1084

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