Definition
Are defined as cellular factors that do not bind DNA directly but are recruited to the promoters by steroid hormone receptors. These promoters enhance agonist-dependent transcriptional activation by facilitating transcription initiation through interaction with components of the basal transcription machinery. Coactivators also enhance transcriptional activity of SHR by other mechanisms such as modulating alternative RNA splicing.
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© 2008 Springer-Verlag Berlin Heidelberg New York
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(2008). Steroid Hormone Receptor Coactivators. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47648-1_5501
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DOI: https://doi.org/10.1007/978-3-540-47648-1_5501
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-36847-2
Online ISBN: 978-3-540-47648-1
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