Encyclopedia of Cancer

2009 Edition
| Editors: Manfred Schwab

Photochemical Reaction Type-I

Reference work entry
DOI: https://doi.org/10.1007/978-3-540-47648-1_4547

Definition

Of an activated photosensitizer after intersystem crossing to the triplet state. The photosensitizer transfers electrons to a target molecule, often molecular oxygen. Photochemical reactions type-I and type-II cause the production of reactive oxygen (ROS), the cytotoxic product employed in photodynamic therapy for destruction of tumor cells.

 Photodynamic Therapy

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© Springer-Verlag Berlin Heidelberg New York 2008