Definition
PED/PEA-15 is a protein of 131 amino acids and 15 kDa that consists of one N-terminal death-effector-domain (DED) and two phosphorylation sites for PKC (Ser 104) and calcium calmodulin kinase II (Ser 116). PED/PEA-15 inhibits apoptosis by interfering with the recruitment of caspase-8 to activated death receptors and also promotes MAPK signaling pathways.PED/PEA-15
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© 2008 Springer-Verlag Berlin Heidelberg New York
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(2008). Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes-15kDa. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-47648-1_4543
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DOI: https://doi.org/10.1007/978-3-540-47648-1_4543
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-36847-2
Online ISBN: 978-3-540-47648-1
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