Synonym
TORCH infections
Definition
Pathological calcification of the newborn brain is detected on plain radiography or CT examination. The numerous causes include perinatal toxoplasmosis, others i.e. HIV, rubella, cytomegalovirus, herpes (TORCH) infections, metabolic abnormalities, vascular disease, brain infarction, tumours and neurophakomatoses.
Pathology/Histopathology
The pathology in neonatal intracranial calcification varies with the underlying cause.
Each one is discussed in more detail elsewhere in this section.
Clinical Presentation
Some infants with congenital infection, in particular cytomegalovirus present with a small head circumference and infants with toxoplasmosis may have hydrocephalus ( 1) All these infections are generalised infections and the infants may have skin rashes and haemorrhages, hepatosplenomegaly, chorioretinitis and pneumonitis.
The diagnosis of tuberous sclerosisdepends on detecting the characteristic cutaneous lesions and the presence of cardiac...
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Bibliography
Barkovich JA (ed) (2005) Pediatric Neuroimaging. 4th edn.Lippincott Williams and Wilkins, Baltimore
El Ayoubi M, de Bethmann O, Monset‐Couchard M (2003) Lenticulostriate echogenic vessels: clinical and sonographic study of 70 neonatal cases. Pediatr Radiol 33:697–703
Reardon W, Hockey A, Silberstein P et al (1994) Autosomal recessive congenital intrauterine infection‐like syndrome of microcephaly, intracranial calcification and CNS disease. Am J Med Genet 52:58–65
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© 2008 Springer-Verlag Berlin Heidelberg New York
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Donoghue, V. (2008). Calcification, Intracranial, Neonatal. In: Baert, A.L. (eds) Encyclopedia of Diagnostic Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35280-8_359
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DOI: https://doi.org/10.1007/978-3-540-35280-8_359
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-35278-5
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