Encyclopedia of Exercise Medicine in Health and Disease

2012 Edition
| Editors: Frank C. Mooren

Acidosis

  • Michael I. LindingerEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-540-29807-6_3

Synonyms

Definition

Acidosis specifically refers to an increase in the hydrogen ion concentration ([H +]; decrease in pH) of the systemic circulation. There are two main types of acidosis that are associated with exercise and recovery from exercise, and these typically occur together with the contributions of each dependent on where the acidosis is assessed, e.g., contracting skeletal muscle, venous blood draining contracting muscle, and arterial blood [ 4]. A respiratory acidosis is defined as in increase in [H +] caused by or associated with an increase in the partial pressure of carbon dioxide (  PCO2).With a respiratory acidosis there typically occurs an increase in the bicarbonate concentration ([HCO 3]) as described by the Henderson–Hasselbalch equation:
$$ {{\text{K}}_{\text{c}}}\cdot{\text{PC}}{{\text{O}}_2} = \left[ {{{\text{H}}^{+} }} \right]\cdot\left[ {{\text{HC}}{{\text{O}}_3}^{-} } \right] $$
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References

  1. 1.
    Edsall JT, Wyman J (1958) Biophysical chemistry. Academic, New York, p 669Google Scholar
  2. 2.
    Lindinger MI, Heigenhauser GJ (1991) The roles of ion fluxes in skeletal muscle fatigue. Can J Physiol Pharmacol 69:246–253PubMedCrossRefGoogle Scholar
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    Lindinger MI, Heigenhauser GJF, McKelvie RS, Jones NL (1992) Blood ion regulation during repeated maximal exercise and recovery in humans. Am J Physiol Regul Integr Comp Physiol 262:R126–R136Google Scholar
  4. 4.
    Lindinger MI, Kowalchuk JM, Heigenhauser GJF (2005) Applying physicochemical principles to skeletal muscle acid-base status. Am J Physiol Regul Integr Comp Physiol 289:R891–R894, author reply R904PubMedCrossRefGoogle Scholar
  5. 5.
    Lindinger M, Waller A (2008) Muscle and blood acid–base physiology during exercise and in response to training. In: Hinchcliff K, Kaneps AJ, Geor RJ (eds) Equine exercise physiology. Saunders Elsevier, Toronto, pp 350–381CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Human Health and Nutritional SciencesUniversity of GuelphGuelphCanada