Encyclopedia of Exercise Medicine in Health and Disease

2012 Edition
| Editors: Frank C. Mooren

Mitochondrial Polymerase

Reference work entry
DOI: https://doi.org/10.1007/978-3-540-29807-6_2674

An enzyme encoded by the POLG gene that is necessary for mitochondrial DNA replication and biogenesis in humans. POLG mutations are associated with mitochondrial diseases; Alpers’ disease, ataxia-neuropathy disorders, dominant and recessive forms of progressive external ophthalmoplegia.

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© Springer-Verlag Berlin Heidelberg 2012