Synonym
CGRP
Definition
Migraineis a complex, multi-symptom disease affecting 10-16% of the western population. It has a higher prevalence in women than in men. Migraine characteristics are its episodic appearance and symptoms such as unilateral headache, phono- and/or photo-phobia, facial mechanical allodynia and nausea and vomiting (Headache Classification Subcommittee of the International Headache Society 2004). Preceding the headache, 20–30% of the patients experience focal neurological symptoms termed aura. Based on the presence or absence of an aura, migraines are classified as either “classical” migraine (migraine with aura), or “common” migraine (migraine without aura). Generally, a migraine attack can be subdivided into different phases that include the premonitory phase, headache and the postdrome. The prevalence of the different symptoms varies over the phases with e.g. being tired and weary as approximately equally prominent in all phases and “stiff neck” being most...
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Arndt, K., Just, S., Doods, H. (2007). Calcitonin Gene-Related Peptide and Migraine Headaches. In: Schmidt, R., Willis, W. (eds) Encyclopedia of Pain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29805-2_505
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DOI: https://doi.org/10.1007/978-3-540-29805-2_505
Publisher Name: Springer, Berlin, Heidelberg
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