Introduction
Research on the relationship between the autonomic nervous system and pain is a developing field with many facets that are interesting from the biological, pathobiological and clinical point of view. The terms biology and pathobiology are preferred to physiology and pathophysiology, because they include physiological, morphological, biochemical and molecular aspects. This field will be briefly reviewed in a broad context, with focus on the sympathetic nervous system, The peripheral sympathetic noradrenergic neuron will be argued to have, in addition to its conventional function to transmit signals generated in the brain to peripheral target cells (e.g. smooth muscle cells, secretory epithelia, heart cells, neurons of the enteric nervous system etc.), quite different functions that are directly or indirectly related to protection of body tissues and pain. Some of these functions have not been studied as extensively as the function to regulate autonomic target cells (Jänig...
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Jänig, W., Baron, R. (2007). Sympathetic Nervous System and Pain. In: Schmidt, R., Willis, W. (eds) Encyclopedia of Pain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29805-2_4327
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DOI: https://doi.org/10.1007/978-3-540-29805-2_4327
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