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Encyclopedia of Pain pp 1369Cite as

Nociceptive Processing in the Hippocampus and Entorhinal Cortex, Neurophysiology and Pharmacology

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Definition

The hippocampus is the simplest part of the cortex, the allocortex, which, in humans, is arched around the mesencephalon, while in rodents it arches over the thalamus (Amaral and Witter 1995). The various fields of the hippocampus and its layers are illustrated in Figure 1. The principal neurons in the hippocampus are the pyramidal cells that are localized in the stratum pyramidale (Fig. 1).

Figure 1
figure _1_978-3-540-29805-2_2761

Digitized image of Nissl stained transverse section taken through dorsal hippocampus and dentate gyrus (DG) of rat. The hippocampus is sub-divided into various fields, of which the prominent ones are CA1 and CA3. In a dorsal to ventral order in the transverse section, the layers of the hippocampus and DG are: a, alveus (which is as a fiber bundle marking the outer boundary of the hippocampus); o, stratum oriens; p, stratum pyramidale; r, stratum radiatum; l, stratum lacunosum-moleculare; m, stratum moleculare; g, stratum granulosum; h, hilus.

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Authors and Affiliations

  1. Department of Physiology, National University of Singapore, Singapore

    Sanjay Khanna

Authors
  1. Sanjay Khanna
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Editors and Affiliations

  1. Physiological Institute, University of Würzburg, Würzburg, Germany

    Robert F. Schmidt

  2. Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas, USA

    William D. Willis

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© 2007 Springer-Verlag Berlin Heidelberg

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Khanna, S. (2007). Nociceptive Processing in the Hippocampus and Entorhinal Cortex, Neurophysiology and Pharmacology. In: Schmidt, R., Willis, W. (eds) Encyclopedia of Pain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29805-2_2761

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  • DOI: https://doi.org/10.1007/978-3-540-29805-2_2761

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-43957-8

  • Online ISBN: 978-3-540-29805-2

  • eBook Packages: MedicineReference Module Medicine

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