Encyclopedia of Neuroscience

2009 Edition
| Editors: Marc D. Binder, Nobutaka Hirokawa, Uwe Windhorst

Co-transmission

Reference work entry
DOI: https://doi.org/10.1007/978-3-540-29678-2_1303

Definition

Co-transmission refers to the release of more than one neurotransmitter from a single neuron. Co-transmitters may be released together or independently depending on their subcellular storage and the level of activation of the neuron. Often peptides are co-released with small molecules. The co-transmitters may have different release properties and can exert different effects on target neurons.

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