Synonyms
Acne rosacea
Definition and Characteristics
Exclusively human chronic cutaneous disorder characterized by transient and later persistent erythema due to prominent vasodilatation accompanied by telangiectasia, interspersed by episodes of inflammation with evident swelling, papules, and pustules [1]. The disease affects classically the centrofacial region (particularly nose, forehead, cheeks, and chin). Keratoconjuctivitis sicca is present in 40% of the patients, and ocular involvement (blepharitis, conjuctivitis, iritis, iridocyclitis, keratitis) is common in rosacea (5–58%). Rhinophyma (diffuse connective tissue and sebaceous gland hyperplasia of the nose) and extrafacial rosacea (retroauricular region, neck, central chest, and/or back) can also be present. In contrast to acne, no comedones develop in rosacea. A provisional classification system defines four subtypes (erythematotelagiectatic, papulopustular, phymatous, and ocular rosacea) and one variant (granulomatous...
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References
Jansen T, Plewig G (1997) Rosacea: classification and treatment. J R Soc Med 90:144–150
Wilkin J et al. (2002) Standard classification of rosacea: report of the National Rosacea Society expert committee on the classification and staging of rosacea. J Am Acad Dermatol 46:584–587
Bamford JT (2001) Rosacea: current thoughts on origin. Semin Cutan Med Surg 20:199–206
Rebora A (2002) The management of rosacea. Am J Clin Dermatol 3:489–496
van Zuuren EJ et al. (2007) Systematic review of resacea treatments. J Am Acad Dermatol. 56:107–115
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Zouboulis, C.C. (2009). Rosacea. In: Lang, F. (eds) Encyclopedia of Molecular Mechanisms of Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29676-8_1570
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DOI: https://doi.org/10.1007/978-3-540-29676-8_1570
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