Type 2 Diabetes Mellitus (T2DM) in the Arab Society of Israel

  • Abdelnaser ZalanEmail author
  • Rajech Sharkia
Living reference work entry


The ancient Egyptians described clinical features similar to diabetes mellitus about 3000 years ago. In recent years, diabetes had become a worrying pandemic disease. It has increased dramatically worldwide during the last decades and it affects more than 382 million people around the world, of whom 90% are diagnosed with type-2 DM (T2DM). It is rapidly increasing in developing as well as developed countries; moreover, it is even found to be increasing to a higher extent in the Arab world. Behavioral and sociodemographic factors associated with T2DM vary within different societies.

The aim of our current study is to shed a considerable amount of light on the status of diabetes in the Arab society of Israel, in relation to the various risk factors that are associated with T2DM. As this community has certain unique characteristics in relation to other residents of this country, lots of studies had been undertaken to explore and compare the incidence, prevalence, and trends of T2DM between all the residing communities in this holy land. Furthermore, in this book chapter we also attempted to shed light on the current status of diabetes in the Palestinian population living in the same holy land and abroad. In the end of this chapter, our recommendations, suggestions, and conclusions in relation to diabetes prevailing in our society are also included. We hope this chapter to constitute beneficiary information to all readers and knowledge seekers from all over the world.


Arab society in Israel Lifestyle Physical activity Risk factors Sociodemographic factors Type 2 diabetes mellitus (T2DM) 

List of Abbreviations


anno Domini


Acquired immune-deficiency syndrome


Body mass index


Coronary artery disease


Central Bureau of Statistics


Combined glucose tolerance


Coronary heart disease


Cardiovascular disease


Diabetic nephropathy


Diabetes Prevention Program


Diabetic retinopathy


End-stage renal disease


Gestational diabetes mellitus


Hemoglobin bound with glucose


High-density lipoprotein


Human immunodeficiency virus


Health Ministry Organization


International Diabetes Federation


Impaired fasting glucose


Impaired glucose tolerance


Insulin resistance


Low- and no-calorie sweeteners


Middle East and North Africa


Noncommunicable disease


Normal glucose tolerance


Organization for Economic Co-operation and Development


Oral glucose tolerance test


Odds ratio


Physical activity


Type 1 diabetes mellitus


Type 2 Diabetes Mellitus


UK Prospective Diabetes Study


United Nations Relief and Works Agency


United States of America


United States Dollar


World Health Organization


  1. Abdul-Ghani MA, Kher J, Abbas N, Najami T (2005a) Association of high body mass index with low age of disease onset among Arab women with type 2 diabetes in a primary care clinic. SAT 26:18Google Scholar
  2. Abdul-Ghani MA, Sabbah M, Muati B, Dakwar N, Kashkosh H, Minuchin O, Vardi P, Raz I (2005b) High frequency of pre-diabetes, undiagnosed diabetes and metabolic syndrome among overweight Arabs in Israel. SAT 1:18Google Scholar
  3. Abdul-Ghani MA, Sabbah M, Kher J, Minuchin O, Vardi P, Raz I (2006) Different contributions of insulin resistance and beta-cell dysfunction in overweight Israeli Arabs with IFG and IGT. Diabetes Metab Res Rev 22(2):126–130PubMedCrossRefGoogle Scholar
  4. Abdul-Rahim HF, Husseini A, Bjertness E, Giacaman R, Gordon NH, Jervell J (2001) The metabolic syndrome in the West Bank population: an urban-rural comparison. Diabetes Care 24(2):275–279PubMedCrossRefGoogle Scholar
  5. Abubakar II, Tillmann T, Banerjee A (2015) Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 385(9963):117–171CrossRefGoogle Scholar
  6. Abu-Rmeileh NM, Husseini A, O’Flaherty M, Shoaibi A, Capewell S (2012) Forecasting prevalence of type 2 diabetes mellitus in Palestinians to 2030: validation of a predictive model. Lancet 380:S21CrossRefGoogle Scholar
  7. Abu-Rmeileh NM, Husseini A, Capewell S, O’Flaherty M (2013) Preventing type 2 diabetes among Palestinians: comparing five future policy scenarios. BMJ Open 3(12):e003558PubMedPubMedCentralCrossRefGoogle Scholar
  8. Abu-Saad K, Murad H, Lubin F, Freedman LS, Ziv A, Alpert G, Atamna A, Kalter-Leibovici O (2012) Jews and Arabs in the same region in Israel exhibit major differences in dietary patterns–3. J Nutr 142(12):2175–2181PubMedCrossRefGoogle Scholar
  9. Action to Control Cardiovascular Risk in Diabetes Study Group (2008) Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 358(24):2545–2559CrossRefGoogle Scholar
  10. Ahmed AM (2002) History of diabetes mellitus. Saudi Med J 23(4):373–378PubMedGoogle Scholar
  11. Akter S, Goto A, Mizoue T (2017) Smoking and the risk of type 2 diabetes in Japan: a systematic review and meta-analysis. J Epidemiol 27(12):553–561PubMedPubMedCentralCrossRefGoogle Scholar
  12. Al-Halaweh AA, Davidovitch N, Almdal TP, Cowan A, Khatib S, Nasser-Eddin L, Baradia Z (2017) Prevalence of type 2 diabetes mellitus complications among Palestinians with T2DM. Diabetes Metab Syndr Clin Res Rev 11:S783–S787CrossRefGoogle Scholar
  13. Alharbi NS, Almutari R, Jones S, Al-Daghri N, Khunti K, de Lusignan S (2014) Trends in the prevalence of type 2 diabetes mellitus and obesity in the Arabian Gulf States: systematic review and meta-analysis. Diabetes Res Clin Pract 106(2):e30–e33PubMedCrossRefGoogle Scholar
  14. Ali MK, Bullard KM, Saaddine JB, Cowie CC, Imperatore G, Gregg EW (2013) Achievement of goals in US diabetes care, 1999–2010. N Engl J Med 368(17):1613–1624PubMedCrossRefGoogle Scholar
  15. ALNohair S (2014) Obesity in gulf countries. Int J Health Sci 8(1):79CrossRefGoogle Scholar
  16. American Diabetes Association (2002) Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications. Diabetes Care 25(1):202–212CrossRefGoogle Scholar
  17. American Diabetes Association (2014) Diagnosis and classification of diabetes mellitus. Diabetes Care 37(Supplement 1):S81–S90CrossRefGoogle Scholar
  18. Amkraut J, Zaina A, Abu-Rabia Y (2018) Diabetes in the Bedouin population in the Israeli Negev–an update 2017. Diabetes Res Clin Pract 140:55–60PubMedCrossRefGoogle Scholar
  19. Aravind SR, Tayeb KA, Ismail SB, Shehadeh N, Kaddaha G, Liu R, Balshaw R, Lesnikova N, Heisel O, Girman CJ, Musser BJ (2011) Hypoglycaemia in sulphonylurea-treated subjects with type 2 diabetes undergoing Ramadan fasting: a five-country observational study. Curr Med Res Opin 27(6):1237–1242PubMedCrossRefGoogle Scholar
  20. Atlas ID (2011) International Diabetes Federation. IDF Diabetes Atlas, 5th edn. Brussels, BelgiumGoogle Scholar
  21. Atlas ID (2013) International Diabetes Federation. IDF Diabetes Atlas. 6th edn. Brussels, BelgiumGoogle Scholar
  22. Atlas ID (2015) International Diabetes Federation. IDF diabetes Atlas, 7th edn. Brussels, BelgiumGoogle Scholar
  23. Atlas ID (2017) International Diabetes Federation. IDF diabetes Atlas, 8th edn. Brussels, BelgiumGoogle Scholar
  24. Badran M, Laher I (2011) Obesity in Arabic-speaking countries. J Obes 2011:1–9CrossRefGoogle Scholar
  25. Balk EM, Earley A, Raman G, Avendano EA, Pittas AG, Remington PL (2015) Combined diet and physical activity promotion programs to prevent type 2 diabetes among persons at increased risk: a systematic review for the Community Preventive Services Task Force. Ann Intern Med 163(6):437–451PubMedPubMedCentralCrossRefGoogle Scholar
  26. Bardini G, Barbaro V, Romano D, Rotella CM, Giannini S (2014) Different distribution of phenotypes and glucose tolerance categories associated with two alternative proposed cutoffs of insulin resistance. Acta Diabetol 51(2):321–324PubMedCrossRefGoogle Scholar
  27. Baron-Epel O, Haviv-Messika A, Tamir D, Nitzan-Kaluski D, Green M (2004) Multiethnic differences in smoking in Israel: pooled analysis from three national surveys. Eur J Public Health 14(4):384–389PubMedCrossRefGoogle Scholar
  28. Baron-Epel O, Kaplan G, Haviv-Messika A, Tarabeia J, Green MS, Kaluski DN (2005) Self-reported health as a cultural health determinant in Arab and Jewish Israelis: MABAT—National Health and Nutrition Survey 1999–2001. Soc Sci Med 61(6):1256–1266PubMedCrossRefGoogle Scholar
  29. Basu S, Yudkin JS, Berkowitz SA, Jawad M, Millett C (2018) Reducing chronic disease through changes in food aid: a microsimulation of nutrition and cardiometabolic disease among Palestinian refugees in the Middle East. PLoS Med 15(11):e1002700PubMedPubMedCentralCrossRefGoogle Scholar
  30. Batniji R, Rabaia Y, Nguyen-Gillham V, Giacaman R, Sarraj E, Punamaki RL, Saab H, Boyce W (2009) Health as human security in the occupied Palestinian territory. Lancet 373(9669):1133–1143PubMedCrossRefGoogle Scholar
  31. Blane D (1995) Social determinants of health--socioeconomic status, social class, and ethnicity. Am J Public Health 85(7):903–905PubMedPubMedCentralCrossRefGoogle Scholar
  32. Calderon-Margalit R, Cohen-Dadi M, Opas D, Jaffe DH, Levine J, Ben-Yehuda A, Paltiel O, Manor O (2018) Trends in the performance of quality indicators for diabetes care in the community and in diabetes-related health status: an Israeli ecological study. Isr J Health Policy Res 7(1):10PubMedPubMedCentralCrossRefGoogle Scholar
  33. Cassel J (1976) The contribution of the social environment to host resistance: the Fourth Wade Hampton Frost Lecture. Am J Epidemiol 104(2):107–123PubMedCrossRefGoogle Scholar
  34. Catalano PM, Shankar K (2017) Obesity and pregnancy: mechanisms of short term and long term adverse consequences for mother and child. BMJ 356:j1PubMedCrossRefGoogle Scholar
  35. Cefalu WT, Buse JB, Tuomilehto J, Fleming GA, Ferrannini E, Gerstein HC, Bennett PH, Ramachandran A, Raz I, Rosenstock J, Kahn SE (2016) Update and next steps for real-world translation of interventions for type 2 diabetes prevention: reflections from a diabetes care editors’ expert forum. Diabetes care 39:1186–1201PubMedPubMedCentralCrossRefGoogle Scholar
  36. Central Bureau of Statistics, Israel (2014) Statistical abstract of Israel 2014.
  37. Central Bureau of Statistics, Israel (2015) Life expectancy by age, sex, and population group. In: Israel statistical abstract 2015. Available at: Accessed 10 Jan 2018
  38. Central Bureau of Statistics, Israel (2016) Available in
  39. Central Bureau of Statistics, Israel (2013) 65th Independence Day. Available from
  40. Chatterjee S, Khunti K, Davies MJ (2017) Type 2 diabetes. Lancet 389(10085):2239–2251PubMedCrossRefGoogle Scholar
  41. Chatterji S, Fogel D (2018) Study of the effect of the herbal composition SR2004 on hemoglobin A1c, fasting blood glucose, and lipids in patients with type 2 diabetes mellitus. Integr Med Res 7(3):248–256PubMedPubMedCentralCrossRefGoogle Scholar
  42. Churuangsuk C, Kherouf M, Combet E, Lean M (2018) Low‐carbohydrate diets for overweight and obesity: a systematic review of the systematic reviews. Obes Rev 19(12):1700–1718PubMedCrossRefGoogle Scholar
  43. Cohen AD, Dreiher J, Regev-Rosenberg S, Yakovson O, Lieberman N, Goldfracht M, Balicer RD (2010) The quality indicators program in Clalit Health Services: the first decade. Harefuah 149(4):204–209PubMedGoogle Scholar
  44. Connolly V, Unwin N, Sherriff P, Bilous R, Kelly W (2000) Diabetes prevalence and socioeconomic status: a population based study showing increased prevalence of type 2 diabetes mellitus in deprived areas. J Epidemiol Community Health 54(3):173–177PubMedPubMedCentralCrossRefGoogle Scholar
  45. Custer Jr, S (2010) United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA): Protection and assistance to Palestine refugees. In International Law and the Israeli-Palestinian Conflict (pp. 55–78). New York, NY: RoutledgeGoogle Scholar
  46. Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang YH, Stevens GA, Rao M (2011) National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2· 7 million participants. Lancet 378(9785):31–40PubMedPubMedCentralCrossRefGoogle Scholar
  47. Daoud N (2008) Challenges facing minority women in achieving good health: voices of Arab women in Israel. Women Health 48(2):145–166PubMedCrossRefGoogle Scholar
  48. Díaz-López A, Babio N, Martínez-González MA, Corella D, Amor AJ, Fitó M, Estruch R, Arós F, Gómez-Gracia E, Fiol M, Lapetra J (2015) Mediterranean diet, retinopathy, nephropathy, and microvascular diabetes complications: a post hoc analysis of a randomized trial. Diabetes care 38(11):2134–2141PubMedCrossRefGoogle Scholar
  49. Dijkstra A, Janssen F, De Bakker M, Bos J, Lub R, Van Wissen LJ, Hak E (2013) Using spatial analysis to predict health care use at the local level: a case study of type 2 diabetes medication use and its association with demograpHic change and socioeconomic status. PLoS One 8(8):e72730PubMedPubMedCentralCrossRefGoogle Scholar
  50. Ding D, Lawson KD, Kolbe-Alexander TL, Finkelstein EA, Katzmarzyk PT, Van Mechelen W, Pratt M, Lancet Physical Activity Series 2 Executive Committee (2016) The economic burden of physical inactivity: a global analysis of major non-communicable diseases. Lancet 388(10051):1311–1324PubMedCrossRefGoogle Scholar
  51. Dwolatzky T, Brodsky J, Azaiza F, Clarfield AM, Jacobs JM, Litwin H (2017) Coming of age: health-care challenges of an ageing population in Israel. Lancet 389(10088):2542–2550PubMedCrossRefGoogle Scholar
  52. el Bilbeisi AH, Hosseini S, Djafarian K (2017) Association of dietary patterns with diabetes complications among type 2 diabetes patients in Gaza strip, Palestine: a cross sectional study. J Health Popul Nutr 36(1):37PubMedPubMedCentralCrossRefGoogle Scholar
  53. Elsous A, Radwan M, Al-Sharif H, Abu Mustafa A (2017) Medications adherence and associated factors among patients with type 2 diabetes mellitus in the Gaza Strip, Palestine. Front Endocrinol 8:100CrossRefGoogle Scholar
  54. Evans JL, Goldfine ID (2016) A new road for treating the vascular complications of diabetes: so let’s step on the gas. Diabetes 65(2):346–348PubMedCrossRefGoogle Scholar
  55. Feldman AL, Griffin SJ, Ahern AL, Long GH, Weinehall L, Fhärm E, Norberg M, Wennberg P (2017) Impact of weight maintenance and loss on diabetes risk and burden: a population-based study in 33,184 participants. BMC Public Health 17(1):170PubMedPubMedCentralCrossRefGoogle Scholar
  56. Feng J, Glass TA, Curriero FC, Stewart WF, Schwartz BS (2010) The built environment and obesity: a systematic review of the epidemiologic evidence. Health Place 16(2):175–190PubMedCrossRefGoogle Scholar
  57. Fried M, Yumuk V, Oppert JM, Scopinaro N, Torres A, Weiner R, Yashkov Y, Frühbeck G (2014) Interdisciplinary European guidelines on metabolic and bariatric surgery. Obes Surg 24(1):42–55CrossRefPubMedGoogle Scholar
  58. Fujimoto WY, Bergstrom RW, Boyko EJ, Leonetti DL, Newell-Morris LL, Wahl PW (1995) Susceptibility to development of central adiposity among populations. Obes Res 3(S2):179s–186sPubMedCrossRefGoogle Scholar
  59. Gavin JR III, Alberti KGMM, Davidson MB, DeFronzo RA (1997) Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 20(7):1183CrossRefGoogle Scholar
  60. Gersh B (2012) The epidemic of cardiovascular disease in the developing world: Global implications. Circulation 2012, 126(21 Supplement):A606Google Scholar
  61. Ghandour R, Mikki N, Rmeileh NMA, Jerdén L, Norberg M, Eriksson JW, Husseini A (2018) Complications of type 2 diabetes mellitus in Ramallah and al-Bireh: the Palestinian diabetes complications and control study (PDCCS). Prim Care Diabetes 12(6):547–557PubMedCrossRefGoogle Scholar
  62. Giacaman R, Khatib R, Shabaneh L, Ramlawi A, Sabri B, Sabatinelli G, Khawaja M, Laurance T (2009) Health status and health services in the occupied Palestinian territory. Lancet 373(9666):837–849CrossRefGoogle Scholar
  63. Goodkin DA, Bragg-Gresham JL, Koenig KG, Wolfe RA, Akiba T, Andreucci VE, Saito A, Rayner HC, Kurokawa K, Port FK, Held PJ (2003) Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the Dialysis Outcomes and Practice Patterns Study (DOPPS). J Am Soc Nephrol 14(12):3270–3277PubMedCrossRefGoogle Scholar
  64. Greenberg E, Treger I, Schwarz J (2011) Age, gender and risk factor disparities in first-stroke Jewish and Arab patients in Israel undergoing rehabilitation. IMAJ-Isr Med Assoc J 13(11):680Google Scholar
  65. Grol R, Grimshaw J (2003) From best evidence to best practice: effective implementation of change in patients’ care. Lancet 362(9391):1225–1230PubMedPubMedCentralCrossRefGoogle Scholar
  66. Gross R, Rosen B, Shirom A (2001) Reforming the Israeli health system: findings of a 3-year evaluation. Health Policy 56(1):1–20PubMedCrossRefGoogle Scholar
  67. Gross B, Feldman-Idov Y, Molshatzki N, Azrilin O, Goldbourt U, Bornstein NM, Tanne D, National Acute Stroke Israeli Survey Study Group (2011) Ethnic variations in acute ischemic stroke: findings from the National Acute Stroke Israeli Survey (NASIS). Cerebrovasc Dis 31(5):506–510PubMedCrossRefGoogle Scholar
  68. Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M (1998) Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 339(4):229–234PubMedPubMedCentralCrossRefGoogle Scholar
  69. Hansen S, Huttunen-Lenz M, Sluik D, Brand-Miller J, Drummen M, Fogelholm M, Handjieva-Darlenska T, Macdonald I, Martinez AJ, Larsen TM, Poppitt S (2018) Demographic and social-cognitive factors associated with weight loss in overweight, pre-diabetic participants of the PREVIEW study. Int J Behav Med 25(6):682–692PubMedPubMedCentralCrossRefGoogle Scholar
  70. Horikawa C, Yoshimura Y, Kamada C, Tanaka S, Tanaka S, Hanyu O, Araki A, Ito H, Tanaka A, Ohashi Y, Akanuma Y (2014) Dietary sodium intake and incidence of diabetes complications in Japanese patients with type 2 diabetes: analysis of the Japan Diabetes Complications Study (JDCS). J Clin Endocrinol Metabol 99(10):3635–3643CrossRefGoogle Scholar
  71. Hu FB (2002) Dietary pattern analysis: a new direction in nutritional epidemiology. Curr Opin Lipidol 13(1):3–9PubMedCrossRefGoogle Scholar
  72. Husseini A, Abu-Rmeileh NM, Mikki N, Ramahi TM, Ghosh HA, Barghuthi N, Khalili M, Bjertness E, Holmboe-Ottesen G, Jervell J (2009) Cardiovascular diseases, diabetes mellitus, and cancer in the occupied Palestinian territory. Lancet 373(9668):1041–1049PubMedCrossRefGoogle Scholar
  73. Idilbi NM, Barhana M, Milman U, Carel RS (2012) Diabetes mellitus and cancer: the different expression of these diseases in Israeli Arabs and Jews. Harefuah 151(11):625–628PubMedGoogle Scholar
  74. Jaacks LM, Siegel KR, Gujral UP, Narayan KV (2016) Type 2 diabetes: a 21st century epidemic. Best Pract Res Clin Endocrinol Metab 30(3):331–343PubMedCrossRefGoogle Scholar
  75. Jabara R, Namouz S, Kark JD, Lotan C (2007) Risk characteristics of Arab and Jewish women with coronary heart disease in Jerusalem. IMAJ-RAMAT GAN 9(4):316Google Scholar
  76. Jaber L, Shohat T, Rotter JI, Shohat M (1997) Consanguinity and common adult diseases in Israeli Arab communities. Am J Med Genet 70(4):346–348PubMedCrossRefGoogle Scholar
  77. Jaffe A, Giveon S, Wulffhart L, Oberman B, Baidousi M, Ziv A, Kalter-Leibovici O (2017) Adult Arabs have higher risk for diabetes mellitus than Jews in Israel. PLoS One 12(5):e0176661PubMedPubMedCentralCrossRefGoogle Scholar
  78. James WPT (2008) The epidemiology of obesity: the size of the problem. J Intern Med 263(4):336–352PubMedCrossRefGoogle Scholar
  79. Jensen MD, Ryan DH, Apovian CM, Ard JD, Comuzzie AG, Donato KA, Hu FB, Hubbard VS, Jakicic JM, Kushner RF, Loria CM (2014) 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Obesity Society. J Am Coll Cardiol 63(25 Part B):2985–3023PubMedCrossRefGoogle Scholar
  80. Kahn SE, Cooper ME, Del Prato S (2014) Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future. Lancet 383(9922):1068–1083PubMedCrossRefGoogle Scholar
  81. Kalter-Leibovici O, Atamna A, Lubin F, Alpert G, Keren MG, Murad H, Chetrit A, Goffer D, Eilat-Adar S, Goldbourt U (2007) Obesity among Arabs and Jews in Israel: a population-based study. IMAJ-RAMAT GAN 9(7):525–530Google Scholar
  82. Kalter-Leibovici O, Younis-Zeidan N, Atamna A, Lubin F, Alpert G, Chetrit A, Novikov I, Daoud N, Freedman LS (2010) Lifestyle intervention in obese Arab women: a randomized controlled trial. Arch Intern Med 170(11):970–976PubMedCrossRefGoogle Scholar
  83. Kalter-Leibovici O, Chetrit A, Lubin F, Atamna A, Alpert G, Ziv A, Abu-Saad K, Murad H, Eilat-Adar S, Goldbourt U (2012) Adult-onset diabetes among Arabs and Jews in Israel: a population-based study. Diabet Med 29(6):748–754PubMedCrossRefGoogle Scholar
  84. Kant AK (2004) Dietary patterns and health outcomes. J Am Diet Assoc 104(4):615–635PubMedCrossRefGoogle Scholar
  85. Kark JD, Gordon ES, Haklai Z (2000) Coronary heart disease mortality among Arab and Jewish residents of Jerusalem. Lancet 356(9239):1410–1411PubMedCrossRefGoogle Scholar
  86. Kark JD, Fink R, Adler B, Goldberger N, Goldman S (2006) The incidence of coronary heart disease among Palestinians and Israelis in Jerusalem. Int J Epidemiol 35(2):448–457PubMedCrossRefGoogle Scholar
  87. Keinan-Boker L, Noyman N, Chinich A, Green MS, Nitzan-Kaluski D (2005) Overweight and obesity prevalence in Israel: findings of the first national health and nutrition survey (MABAT). Isr Med Assoc J 7(4):219–223PubMedGoogle Scholar
  88. Khader A, Farajallah L, Shahin Y, Hababeh M, Abu-Zayed I, Kochi A, Harries AD, Zachariah R, Kapur A, Venter W, Seita A (2012a) Cohort monitoring of persons with hypertension: an illustrated example from a primary healthcare clinic for Palestine refugees in Jordan. Tropical Med Int Health 17(9):1163–1170CrossRefGoogle Scholar
  89. Khader A, Farajallah L, Shahin Y, Hababeh M, Abu-Zayed I, Kochi A, Harries AD, Zachariah R, Kapur A, Venter W, Seita A (2012b) Cohort monitoring of persons with diabetes mellitus in a primary healthcare clinic for Palestine refugees in Jordan. Tropical Med Int Health 17(12):1569–1576CrossRefGoogle Scholar
  90. Khatib M, Efrat S, Deeb D (2007) Knowledge, beliefs, and economic barriers to healthcare: a survey of diabetic patients in an Arab-Israeli town. J Ambul Care Manage 30(1):79–85PubMedCrossRefGoogle Scholar
  91. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346(6):393–403PubMedCrossRefGoogle Scholar
  92. Ladabaum U, Mannalithara A, Myer PA, Singh G (2014) Obesity, abdominal obesity, physical activity, and caloric intake in US adults: 1988 to 2010. Am J Med 127(8):717–727PubMedPubMedCentralCrossRefGoogle Scholar
  93. Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT, Lancet Physical Activity Series Working Group (2012) Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet 380(9838):219–229PubMedPubMedCentralCrossRefGoogle Scholar
  94. Link BG, Phelan J (1995) Social conditions as fundamental causes of disease. J Health Soc Behav, 80–94CrossRefGoogle Scholar
  95. Mahoney SE, Loprinzi PD (2014) Influence of flavonoid-rich fruit and vegetable intake on diabetic retinopathy and diabetes-related biomarkers. J Diabetes Complicat 28(6):767–771PubMedCrossRefGoogle Scholar
  96. Mainous AG, Tanner RJ, Baker R, Zayas CE, Harle CA (2014) Prevalence of prediabetes in England from 2003 to 2011: population-based, cross-sectional study. BMJ Open 4(6):e005002PubMedPubMedCentralCrossRefGoogle Scholar
  97. Marmot M (2005) Social determinants of health inequalities. Lancet 365(9464):1099–1104CrossRefPubMedGoogle Scholar
  98. Meo SA, Al-Drees M, Arif M, Al-Rubean K (2006) Lung function in type 2 Saudi diabetic patients. Saudi Med J 27(3):338–343PubMedGoogle Scholar
  99. Meo SA, Usmani AM, Qalbani E (2017) Prevalence of type 2 diabetes in the Arab world: impact of GDP and energy consumption. Eur Rev Med Pharmacol Sci 21:1303–1312PubMedGoogle Scholar
  100. Merom D, Sinnreich R, Aboudi V, Kark JD, Nassar H (2012) Lifestyle physical activity among urban Palestinians and Israelis: a cross-sectional comparison in the Palestinian-Israeli Jerusalem risk factor study. BMC Public Health 12(1):90PubMedPubMedCentralCrossRefGoogle Scholar
  101. Millen BE, Abrams S, Adams-Campbell L, Anderson CA, Brenna JT, Campbell WW, Clinton S, Hu F, Nelson M, Neuhouser ML, Perez-Escamilla R (2016) The 2015 Dietary Guidelines Advisory Committee Scientific report: development and major conclusions. Adv Nutr 7(3):438–444PubMedPubMedCentralCrossRefGoogle Scholar
  102. Mirmiran P, Bahadoran Z, Azizi F (2014) Functional foods-based diet as a novel dietary approach for management of type 2 diabetes and its complications: a review. World J Diabetes 5(3):267PubMedPubMedCentralCrossRefGoogle Scholar
  103. Misra R, Balagopal P, Raj S, Patel TG (2018) Red meat consumption (Heme Iron intake) and risk for diabetes and comorbidities? Curr Diab Rep 18(11):100PubMedCrossRefGoogle Scholar
  104. Mokdad AH (2018) Diabetes mellitus and chronic kidney disease in the Eastern Mediterranean Region: findings from the Global Burden of Disease 2015 study. Int J Public Health 63:177–186Google Scholar
  105. Morgan CL, Currie CJ, Peters JR (2000) Relationship between diabetes and mortality: a population study using record linkage. Diabetes Care 23(8):1103–1107PubMedCrossRefGoogle Scholar
  106. Musaiger AO (1992) Diabetes mellitus in Bahrain: an overview. Diabet Med 9(6):574–578PubMedCrossRefGoogle Scholar
  107. Na’amnih W, Muhsen K, Tarabeia J, Saabneh A, Green MS (2010) Trends in the gap in life expectancy between Arabs and Jews in Israel between 1975 and 2004. Int J Epidemiol 39(5):1324–1332PubMedCrossRefGoogle Scholar
  108. Naseem S, Khattak UK, Ghazanfar H, Irfan A (2016) Prevalence of non-communicable diseases and their risk factors at a semi-urban community, Pakistan. Pan Afr Med J 23:151.
  109. National Insurance Institute, Israel (2015) The 2014 poverty report. Israel National Insurance Institute, JerusalemGoogle Scholar
  110. National Research Council (USA) Committee on Diet and Health (1989) Diet and health: implications for reducing chronic disease risk. Washington (DC): National Academies Press (USA)Google Scholar
  111. NCD Risk Factor Collaboration (2016) Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4· 4 million participants. Lancet 387(10027):1513–1530CrossRefGoogle Scholar
  112. Neuhouser ML (2018) The importance of healthy dietary patterns in chronic disease prevention. Nutr Res pii: S0271-5317(18)30222-7Google Scholar
  113. Ng SW, Zaghloul S, Ali HI, Harrison G, Popkin BM (2011) The prevalence and trends of overweight, obesity and nutrition-related non-communicable diseases in the Arabian Gulf States. Obes Rev 12(1):1–13PubMedCrossRefGoogle Scholar
  114. Nikoloski Z, Williams G (2016) Obesity in Middle East. In: Ahima RS (eds) Metabolic Syndrome, p. 55–72. Springer, ChamCrossRefGoogle Scholar
  115. Nseir W, Haj S, Beshara B, Mograbi J, Cohen O (2013) Seeking out high risk population: the prevalence characteristics and outcome of diabetic patients of Arab ethnicity hospitalized in internal medical and acute coronary units in Israel. Int J Endocrinol 2013:1–6CrossRefGoogle Scholar
  116. Ogurtsova K, da Rocha Fernandes JD, Huang Y, Linnenkamp U, Guariguata L, Cho NH, Cavan D, Shaw JE, Makaroff LE (2017) IDF diabetes Atlas: global estimates for the prevalence of diabetes for 2015 and 2040. Diabetes Res Clin Pract 128:40–50CrossRefPubMedGoogle Scholar
  117. Palaniappan LP, Carnethon MR, Fortmann SP (2002) Heterogeneity in the relationship between ethnicity, BMI, and fasting insulin. Diabetes Care 25(8):1351–1357PubMedPubMedCentralCrossRefGoogle Scholar
  118. Palestinian Ministry of Health (2016) MoH annual health report 2015, MoH, PalestineGoogle Scholar
  119. Patel N, Ferrer HB, Tyrer F, Wray P, Farooqi A, Davies MJ, Khunti K (2017) Barriers and facilitators to healthy lifestyle changes in minority ethnic populations in the UK: a narrative review. J Racial Ethn Health Disparities 4(6):1107–1119PubMedCrossRefGoogle Scholar
  120. Pieris RR, Al-Sabti HA, Al-Abri QSA, Rizvi SGA (2014) Prevalence pattern of risk factors for coronary artery disease among patients presenting for coronary artery bypass grafting in Oman. Oman Med J 29(3):203PubMedPubMedCentralCrossRefGoogle Scholar
  121. Prasad RB, Groop L (2015) Genetics of type 2 diabetes-pitfalls and possibilities. Genes (Basel) 6:87–123CrossRefGoogle Scholar
  122. Qlalweh K, Duraidi M, Brønnum-Hansen H (2012) Health expectancy in the occupied Palestinian territory: estimates from the Gaza Strip and the West Bank: based on surveys from 2006 to 2010. BMJ Open 2(6):e001572.sCrossRefGoogle Scholar
  123. Rahim HFA, Sibai A, Khader Y, Hwalla N, Fadhil I, Alsiyabi H, Mataria A, Mendis S, Mokdad AH, Husseini A (2014) Non-communicable diseases in the Arab world. Lancet 383(9914):356–367PubMedCrossRefGoogle Scholar
  124. Reaven GM (1995) Pathophysiology of insulin resistance in human disease. Physiol Rev 75(3):473–486PubMedCrossRefGoogle Scholar
  125. Relief, U.N. (2007) Works agency. Annual report of the department of health. United Nations Relief and Works Agency, AmmanGoogle Scholar
  126. Robertson T, Alzaabi A, Robertson M, Fielding B (2018) Starchy carbohydrates in a healthy diet: the role of the humble potato. Nutrients 10(11):1764PubMedCentralCrossRefGoogle Scholar
  127. Rytter MJH, Kjældgaard AL, Brønnum-Hansen H, Helweg-Larsen K (2006) Effects of armed conflict on access to emergency health care in Palestinian West Bank: systematic collection of data in emergency departments. BMJ 332(7550):1122–1124PubMedPubMedCentralCrossRefGoogle Scholar
  128. Saabneh AM (2015) Arab–Jewish gap in life expectancy in Israel. Eur J Public Health 26(3):433–438PubMedCrossRefGoogle Scholar
  129. Sagar AD, Najam A (1998) The human development index: a critical review1. Ecol Econ 25(3):249–264CrossRefGoogle Scholar
  130. Salameh S, Hochner-Celnikier D, Chajek-Shaul T, Manor O, Bursztyn M (2008) Ethnic gap in coronary artery disease: comparison of the extent, severity, and risk factors in Arab and Jewish middle-aged women. J Cardiometab Syndr 3(1):26–29PubMedCrossRefGoogle Scholar
  131. Schulz M, Romppel M, Grande G (2016) Built environment and health: a systematic review of studies in Germany. J Public Health 40(1):8–15Google Scholar
  132. Seixas AA, Gyamfi L, Newsome V, Ranger-Murdock G, Butler M, Rosenthal DM, Zizi F, Youssef I, McFarlane SI, Jean-Louis G (2018) Moderating effects of sleep duration on diabetes risk among cancer survivors: analysis of the National Health Interview Survey in the USA. Cancer Manag Res 10:4575PubMedPubMedCentralCrossRefGoogle Scholar
  133. Serra-Majem L, Raposo A, Aranceta-Bartrina J, Varela-Moreiras G, Logue C, Laviada H, Socolovsky S, Pérez-Rodrigo C, Aldrete-Velasco J, Meneses Sierra E, López-García R (2018) Ibero–American consensus on low-and no-calorie sweeteners: safety, nutritional aspects and benefits in food and beverages. Nutrients 10(7):818PubMedCentralCrossRefGoogle Scholar
  134. Seshasai SRK (2011) Diabetes mellitus, fasting glucose, and risk of cause-specific death (vol 364, pg 829, 2011). N Engl J Med 364(13):1281–1281Google Scholar
  135. Seuring T, Archangelidi O, Suhrcke M (2015) The economic costs of type 2 diabetes: a global systematic review. PharmacoEconomics 33(8):811–831PubMedPubMedCentralCrossRefGoogle Scholar
  136. Shalata A, Jazmawi W, Aslan O, Badarni K, Dabbah K, Sawaed S, Castel OC, Borochowitz ZU, Karkabi K, Defronzo R, Abdul-Ghani M (2013) Early metabolic defects in Arab subjects with strong family history of type 2 diabetes. J Endocrinol Investig 36(6):417–421Google Scholar
  137. Sharif K, Watad A, Coplan L, Amital H, Shoenfeld Y, Afek A (2018) Psychological stress and type 1 diabetes mellitus: what is the link? Expert Rev Clin Immunol 14(12):1081–1088PubMedCrossRefGoogle Scholar
  138. Sharkia R, Mahajnah M, Athamny E, Khatib M, Sheikh-Muhammad A, Zalan A (2016) Changes in marriage patterns among the Arab community in Israel over a 60-year period. J Biosoc Sci 48(2):283–287PubMedCrossRefGoogle Scholar
  139. Sharkia R, Mahajnah M, Sheikh-Muhammad A, Khatib M, Zalan A (2018) Trends in the prevalence of type 2 diabetes mellitus among Arabs in Israel: A community health survey. Global Advanced Research Journal of Medicine and Medical Sciences 7(4):98–104Google Scholar
  140. Sharkia R, Sheikh-Muhammad A, Mahajnah M, Khatib M, Zalan A (2019) Exploration of risk factors for type 2 diabetes among Arabs in Israel. Ann Glob Health 85(1):X, 1–7.
  141. Shawahna R, Shanti Y, Al Zabadi H, Sharabati M, Alawneh A, Shaqu R, Taha I, Bustami A (2018) Prevalence and association of clinical characteristics and biochemical factors with complications of diabetes mellitus in Palestinians treated in primary healthcare practice. Diabetes Metab Syndr Clin Res Rev 12:693–704CrossRefGoogle Scholar
  142. Skaat A, Chetrit A, Belkin M, Kinori M, Kalter-Leibovici O (2012) Time trends in the incidence and causes of blindness in Israel. Am J Ophthalmol 153(2):214–221PubMedCrossRefGoogle Scholar
  143. Statistics, U.N.R.W.A. (2010) Selected indicators. United Nation Relief and Works Agency for Palestine refugees in the Near East, 2011Google Scholar
  144. Suárez AL (2018) Burden of cancer attributable to obesity, type 2 diabetes and associated risk factors. Metabolism 92:136–146CrossRefGoogle Scholar
  145. Sullivan PW, Morrato EH, Ghushchyan V, Wyatt HR, Hill JO (2005) Obesity, inactivity, and the prevalence of diabetes and diabetes-related cardiovascular comorbidities in the US, 2000–2002. Diabetes Care 28(7):1599–1603PubMedCrossRefGoogle Scholar
  146. Swinburn BA, Sacks G, Hall KD, McPherson K, Finegood DT, Moodie ML, Gortmaker SL (2011) The global obesity pandemic: shaped by global drivers and local environments. Lancet 378(9793):804–814PubMedCrossRefGoogle Scholar
  147. Tanaka S, Yoshimura Y, Kawasaki R, Kamada C, Tanaka S, Horikawa C, Ohashi Y, Araki A, Ito H, Akanuma Y, Yamada N (2013) Fruit intake and incident diabetic retinopathy with type 2 diabetes. Epidemiology 24(2):204–211PubMedCrossRefGoogle Scholar
  148. Telman G, Hlebtovsky A, Sprecher E, Zaaroor M, Kouperberg E (2010a) Ethnic disparities in first primary intracerebral hemorrhage in northern Israel. Neuroepidemiology 34(4):208–213PubMedCrossRefGoogle Scholar
  149. Telman G, Kouperberg E, Sprecher E, Yarnitsky D (2010b) Ethnic differences in ischemic stroke of working age in northern Israel. J Stroke Cerebrovasc Dis 19(5):376–381PubMedCrossRefGoogle Scholar
  150. The Israel Center for Disease Control (2006) The state of health of the Arab population of Israel 2004. Ministry of Health, ICDC publication number 226Google Scholar
  151. Tirosh A, Calderon-Margalit R, Mazar M, Stern Z (2008) Differences in quality of diabetes care between Jews and Arabs in Jerusalem. Am J Med Qual 23(1):60–65PubMedCrossRefGoogle Scholar
  152. Treister-Goltzman Y, Peleg R (2015) Literature review of type 2 diabetes mellitus among minority Muslim populations in Israel. World J Diabetes 6(1):192PubMedPubMedCentralCrossRefGoogle Scholar
  153. Troen AM, Fraser D, Abdeen Z, Rosenberg IH (2006) Child nutrition initiative in Israel and Palestine: status of food security, micronutrient malnutrition, and behavioral change and communication programs. Food Nutr Bull 27(2):180–185PubMedCrossRefGoogle Scholar
  154. Turner RC, Cull CA, Frighi V, Holman RR, UK Prospective Diabetes Study (UKPDS) Group (1999) Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). JAMA 281(21):2005–2012PubMedCrossRefGoogle Scholar
  155. UK Prospective Diabetes Study (UKPDS) Group (1998) Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 352(9131):837–853CrossRefGoogle Scholar
  156. United Nations Relief and Works Agency (2018) Health Department annual report. United Nations Relief and World Agency, GenevaGoogle Scholar
  157. Vallianou NG, Stratigou T, Tsagarakis S (2018) Microbiome and diabetes: where are we now? Diabetes Res Clin Pract 146:111–118PubMedCrossRefGoogle Scholar
  158. Vecchio I, Tornali C, Bragazzi NL, Martini M (2018) The discovery of insulin: an important milestone in the history of medicine. Front Endocrinol 9:613CrossRefGoogle Scholar
  159. Waterston T, Nasser D (2017) Access to healthcare for children in Palestine. BMJ Paediatr Open 1(1):e000115PubMedPubMedCentralCrossRefGoogle Scholar
  160. Weiss R, Nassar H, Sinnreich R, Kark JD (2015) Differences in the triglyceride to HDL-cholesterol ratio between Palestinian and Israeli adults. PLoS One 10(1):e0116617PubMedPubMedCentralCrossRefGoogle Scholar
  161. Williams R (2015) The economics of diabetes care: a global perspective. International Textbook of Diabetes Mellitus, Fourth Edition, Swansea University. pp. 1113–1124CrossRefGoogle Scholar
  162. Wilf-Miron R, Tov OS, Lewinhoff I, Yaari E, Avitzour M, Viner A, Porath A, Kokia E (2010a) Equity promotion in maccabi healthcare services: from the equality report to an organizational action plan. Harefuah 149(4):210–213PubMedGoogle Scholar
  163. Wilf-Miron R, Peled R, Yaari E, Shem-Tov O, Weinner VA, Porath A, Kokia E (2010b) Disparities in diabetes care: role of the patient’s socio-demographic characteristics. BMC Public Health 10(1):729PubMedPubMedCentralCrossRefGoogle Scholar
  164. Wilf-Miron R, Bolotin A, Gordon N, Porath A, Peled R (2014) The association between improved quality diabetes indicators, health outcomes and costs: towards constructing a “business case” for quality of diabetes care-a time series study. BMC Endocr Disord 14(1):92PubMedPubMedCentralCrossRefGoogle Scholar
  165. World Bank (2010) Towards a Palestinian state: reforms for fiscal strengthening. World Bank. Final.pdf. Accessed 7 Sep 2012
  166. World Bank data: Arab World (2015) Available at:, cited date 2 Feb 2015
  167. World Health Organization (2006) Obesity and overweight: World Health OrganizationGoogle Scholar
  168. World Health Organization (2014) World Health Statistics—2014. Geneva, SwitzerlandGoogle Scholar
  169. World Health Organization (2016) Global report on diabetes. World Health OrganizationGoogle Scholar
  170. Yitzhaki S (1983) On an extension of the Gini inequality index. Int Econ Rev, 617–628CrossRefGoogle Scholar
  171. Yitzhaki S (2010) Israel in figures: 2010. Jerusalem, Central Bureau of StatisticsGoogle Scholar
  172. Zimmet P, Alberti KG, Magliano DJ, Bennett PH (2016) Diabetes mellitus statistics on prevalence and mortality: facts and fallacies. Nat Rev Endocrinol 12(10):616PubMedCrossRefGoogle Scholar
  173. Zlotogora J (2002) Parental decisions to abort or continue a pregnancy with an abnormal finding after an invasive prenatal test. Prenat Diagn 22(12):1102–1106PubMedCrossRefGoogle Scholar
  174. Zucker I, Arditi-Babchuk H, Enav T, Shohat T (2016) Self-reported type 2 diabetes and diabetes-related eye disease in Jews and Arabs in Israel. J Immigr Minor Health 18(6):1328–1333PubMedCrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Human Biology DepartmentThe Triangle Research and Development CenterKfar-QariIsrael
  2. 2.Beit-Berl Academic CollegeBeit-BerlIsrael

Section editors and affiliations

  • Anastasia Samara
    • 1
  • Atika Khalaf
    • 2
  1. 1.Health PromotionUniversity of Southern DenmarkEsbjergDenmark
  2. 2.Faculty of Health ScienceKristianstad UniversityKristianstadSweden

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