Definition
Bioprospecting or biodiversity prospecting is defined as the systematic search for genes, natural compounds, designs, and whole organisms in wild life with a potential for product development for pharmaceutical, cosmetic, agricultural, and other applications, without disruption to nature (Mateo et al. 2001).
Introduction
Oceans are the largest natural habitat on earth with a substantial biodiversity that occupies approximately 70% of the planet’s surface (Polidoro et al. 2008). They have varying physical and chemical conditions, which causes organisms to exhibit a variety of molecules with unique characteristics (Faulkner 2001; Simmons et al. 2005). The seas and oceans contain a huge source of biological, genetic, and chemical diversity. More than 300,000 plant and animal species are known, of which a small percentage have already resulted in the characterization of over 12,000 new chemical compounds. Marine ecosystem services produce a huge diversity of goods and services...
References
Alino PM, Coll JC (1989) Observations of the synchronized mass spawning and post settlement activity of octocorals on the Great Barrier Reef, Australia: biological aspects. Bull Mar Sci 45:697–707
Alino PM, Sammarco PW, Coll JC (1992) Competitive strategies in soft corals (Coelenterata, Octocorallia). IV. Environmentally induced reversals in competitive superiority. Mar Ecol Prog Ser 81:129–145
Arnaud-Haond S, Arrieta JM, Duarte CM (2011) Marine biodiversity and gene patents. Science 331:1521–1522
Arrieta J, Arnaud-Haond S, Duarte CM (2010) What lies underneath: conserving the ocean’s genetic resources. Proc Natl Acad Sci U S A 107(43):18318–18324
Bakus GJ, Thun M (1979) Bioassays on the toxicity of Caribbean sponges. Colloq Int C N R S 291:417–422
Bakus GJ, Targett NM, Schulte B (1986) Chemical ecology of marine organisms: an overview. J Chem Ecol 12:951–987
Beattie AJ, Barthlott W, Elisabetsky E et al (2005) New products and industries from biodiversity. In: Hassan R, Scholes R, Ash N (eds) Ecosystems and human well-being, Millennium Ecosystem Assessment. Island Press, Washington, DC, pp 273–295
Becker EW (2004) Microalgae in human and animal nutrition. In: Richmond A (ed) Handbook of microalgal culture: biotechnology and applied phycology. Blackwell Science, Oxford, pp 312–351
Blunt JW, Copp BR, Munro MHG, Northcote PT, Prinsep MR (2003) Pectins and their manipulation. Nat Prod Rep 20:1
Blunt JW, Copp BR, Keyzers RA, Munro MHG, Prinsep MR (2012) Marine natural products. Nat Prod Rep 29:144–222
Borowitzka MA (1993) Products from microalgae. Infofish Int 5:21–26
Borowitzka MA (1997) Microalgae for aquaculture: opportunities and constraints. J Appl Phycol 9:393–401
Bowden BF, Coll JC, Tapiolas DM, Willis RH (1985) Some chemical aspects of spawning in Alcyonacean corals. In: Proc. 5th Int. Coral Reef Symp., Tahiti, vol 6, pp 325–329
Britton R, de Oliveira JHHL, Andersen RJ, Berlinck RGSJ (2001) Granulatimide and 6-Bromogranulatimide, Minor Alkaloids of the Brazilian Ascidian Didemnum granulatum. J Nat Prod 64:254–255
Brown MR, Mular M, Miller I, Farmer C, Trenerry C (1999) The vitamin content of microalgae used in aquaculture. J Appl Phycol 11:247–255
Bruno JJ (2001) Edible microalgae: a review of the health research, vol 3. Center for Nutritional Psychology, Pacifica, p 56
Burja AM, Banaigs B, Abou-Mansour E, Burgess JG, Wright PC (2001) Marine Cyanobacteria – a prolific source of natural products. Tetrahedron 57:9347–9377
Calewaert JB, Piniella AM, McDonough N (2012) Marine biotechnology RTDI in Europe – inventory of strategic documents and activities. Deliverable no. 3.5. Inventory report of marine biotechnology RTDI in Europe. Part of Task 3.1. Inventory of marine biotechnology RTDI strategies, programmes and initiatives report. Marine Board-ESF
Camargo JA, Alonso Á (2006) Ecological and toxicological effects of inorganic nitrogen pollution in aquatic ecosystems: a global assessment. Environ Int 32:831–849
Certik M, Shimizu S (1999) Biosynthesis and regulation of microbial polyunsaturated fatty acid production. J Biosci Bioeng 87(1):1–14
Chiaramonti D, Prussi M, Casini D, Tredici MR, Rodolfi L, Bassi N, Zittelli GC, Bondioli P (2013) Review of energy balance in raceway ponds for microalgae cultivation: rethinking a traditional system is possible. Appl Energy 102:101–111
Ciereszko LS, Karns TKB (1973) Comparative biochemistry of coral reef coelenterates. In: Jones OA, Endean R (eds) Biology and geology of coral reefs, biology 1, vol II. Academic Press, New York, pp 183–203
Coll JC (1992) The chemistry and chemical ecology of octocorals (Coelenterata, Anthozoa, Octocorallia). Chem Rev 92:613–631
Coll JC, La Barre SC, Sammarco PW, Williams WT, Bakus GJ (1982) Chemical defences in soft corals (Coelenterata: Octocorallia) of the Great Barrier Reef: a study of comparative toxicities. Mar Ecol Prog Ser 8:271–278. Conservation 78:97–106
Coll JC, Bowden BF, König GM, Braslau R, Price IR (1986) Studies of Australian soft corals. The natural products chemistry of Alcyonacean soft corals with special reference to the genus Lobophytum. Bull Soc Chim Belg 95:815–833
Coll JC, Bowden BF, Alino PN, Heaton A, König GM, De Nys R, Willis RH (1989) Chemically mediated interactions between marine organisms. Chem Scr 29:383–388
Coll JC, Bowden BF, Clayton M (1990) Chemistry and coral reproduction. Chem Br 26:761–763
Colla LM et al (2004) Fatty acids of Spirulina platensis grown under different temperatures and nitrogen concentrations. Z Naturforsch 59c:55–59
Davies-Coleman, MT, Sunassee, SN (2012) Marine bioprospecting in southern Africa. In: Drug discovery in Africa – impacts of geneomics, natural products, traditional medicines, insights into medicinal chemistry, and technology platforms in pursuit of new drugs. (eds. K. Chibale, M. Davies-Coleman, and C. Masimirembwa) pp. 193–209. Springer-Verlag, Berlim
Darzins AL, Pienkos P, Edye L (2010) Current status and potential for algal biofuels production: a report to IEA Bioenergy Task 39: commercializing liquid biofuels from biomass. National Renewable Energy Laboratory, Golden
de la Calle F (2009) Marine genetic resources, a source of new drugs: the experience of the biotechnology sector. Int J Mar Coast Law 24(2):209–220
Duh CY, Wang SK, Weng YL, Chiang MY, Dai CF (1999) Cytotoxic terpenoids from the Formosan soft coral Nephthea brassica. Tetrahedron Lett 41:1401–1403
Duh CY, Wang SK, Weng YL (2000) Brassicolene, a novel cytotoxic diterpenoid from the Formosan soft coral Nephthea brassica. Tetrahedron Lett 41:1401–1403
ECORYS (2014) Study in support of Impact Assessment work on Blue Biotechnology, FWC MARE/2012706 – SC C1/2013/03
Faulkner DJ (2001) Marine natural products. Nat Prod Rep 18:1–49
Fleury BG (1999) Ecologia Química Marinha: Competição por espaço entre corais e efeitos de nutrientes no metabolismo secundário de macroalgas e octocorais. Tese de doutorado. Universidade Federal do Rio de Janeiro, NPPN-CCS, Rio de Janeiro, p 261
Fleury BG, Coll JC, Tentori E, Duquesne S, Figueiredo L (2000) Effect of nutrient enrichment on the complementary (secondary) metabolite composition of the soft coral Sarcophyton ehrenbergi (Cnidaria: Octocorallia: Alcyonacea) of the Great Barrier Reef. Mar Biol 136:63–68
Gerhart DJ (1986) Gregariousness in the gorgonian-eating gastropod Cyphoma gibbosum: tests of several possible causes. Mar Ecol Prog Ser 31:2545–2263
Gill I, Valivety R (1997) Polyunsaturated fatty acids, part 1: occurrence, biological activities and applications. Trends Biotechnol 15:401–409
Global Industry Analysts, Inc. (2015) Marine biotechnology: a global strategic business report. http://www.strategyr.com/pressMCP-1612.asp
Global Ocean Commission (2013) Policy options paper no. 4: bioprospecting and marine genetic resources in the high seas. A series of papers on policy options, prepared for the third meeting of the Global Ocean Commission
Granato AC, Berlinck RG S, Magalhães A, Schefer AB, Ferreira AG, Sanctis B, Freitas JC, Hajdu E, Migotto AE (2000) Produtos naturais das esponjas marinhas Aaptos sp., Hymeniacidon aff. Heliophila, e do nudibrânquio Doris aff. Verrucosa. QUÍMICA NOVA 23(5):594–599
Greiber T (2011) Access and benefit sharing in relation to marine genetic resources from areas beyond national jurisdiction – a possible way forward no. 301. Research project of the Federal Agency for Nature Conservation, German Federal Agency for Nature Conservation, Bundesamt für Naturschutz (BfN), Bonn
Grobbelaar JU (2004) Algal biotechnology: real opportunities for Africa. S Afr J Bot 70(1):140–144
Handayani D, Edrada RA, Proksch P, Wray V, Witte L, van Ofwegen L, Kunzmann A (1997) New oxygenated sesquiterpenes from the Indonesian soft coral Nephthea chabrolii. J Nat Prod 60:716–718
Hay ME (1996) Marine chemical ecology: what’s known and what’s next? J Exp Mar Biol Ecol 200:103–134
Hay ME, Fenical W (1988) Marine plant–herbivore interactions: the ecology of chemical defense. Annu Rev Ecol Syst 19:111–145
Hernandez, A, Zainos A, Romo R (2000) Neuronal correlates of sensory discrimination in the somatosensory cortex. Proc Natl Acad Sci USA 97:6191–6196
Heydarizadeh P, Poirier I, Loizeau D, Ulmann L, Mimouni V, Schoefs B, Bertrand M (2013) Plastids of marine phytoplankton produce bioactive pigments and lipids. Mar Drugs 11:3425–3471
IEA Bioenergy Task 39 and IEA AMF (2011) Algae as a feedstock for biofuels – an assessment of the current status and potential for algal biofuels production. www.task39.org
Johansen SD, Emblem A, Karlsen BO, Okkenhaug S, Hansen H, Moum T, Coucheron DH, Seternes OM (2010) Approaching marine bioprospecting in hexacorals by RNA deep sequencing. New Biotechnol 27:267–275
Kamyab H, Fadhil M, Lee C, Ponraj M, Soltani M, Eva S (2014) Micro–macro algal mixture as a promising agent for treating POME discharge and its potential use as animal feed stock enhancer. J Teknol 68:1–4
Kelecom A (1997) Marine natural products in Brazil. Part 1. Isolation and structure determination. Ciênc Cult 49:321
Kelecom A (1998) Synthesis of marine natural products in Brazil. J Braz Chem Soc 9:101
Kijjoa A, Sawangwong P (2004) Drugs and cosmetics from the sea. Mar Drugs 2:73–82
Kirk EA, Behrens PW (1999) Commercial developments in microalgal biotechnology. J Phycol 35:215–226
Koehn FE, Carter GT (2005) Rediscovering natural products as a source of new drugs. Discov Med 26:159–164
La Barre SC, Coll JC, Sammarco PW (1986) Defensive strategies of soft corals (Coelenterata: Octocorallia) of the Great Barrier Reef. II. The relationship between toxicity and feeding deterrence. Biol Bull 171:565–576
Laird DW, Rowen CC, Machold T, May PM, Hefter GT (2013) Volatile products from the degradation of organics in a synthetic Bayer liquor. Ind Eng Chem Res 52(10):3613
Laird S (2013) Bioscience at a Crossroads: Access and Benefit Sharing in a Time of Scientific, Technological and Industry Change: The Pharmaceutical Industry. Secretariat of the CBD, Toronto
Leal MC, Calado RC (2015) Marine natural products: biodiscovery, biodiversity and bioproduction. In: Brahmachari G (ed) Bioactive natural products: chemistry and biology. Wiley, Weinheim, pp 473–490
Leal MC, Puga J (2012) Trends in the discovery of new marine natural products from invertebrates over the last two decades – where and what are we bioprospecting? PLoS One 7(1):e30580
Leal MC, Sheridan C, Osinga R, Dionisio G, Rocha RJM, Silva B, Rosa R, Calado R (2014) Marine microorganism-invertebrate assemblages: perspectives to solve the “supply problem” in the initial steps of drug discovery. Mar Drugs 12(7):3929–3952
Leman J (1997) Oleaginous microorganisms: an assessment of the potential. Adv Appl Microbiol 51:195–243
Lindsay B, Almeida AMP, Smith C, Rocha RM, Berlinck RGS, Ireland CM (1999) 6-Methoxy-7-methyl-8-oxoguanine, an unusual purine from the ascidian Symplegma rubra. J Nat Prod 62:1573
Liu D, Keesing JK, He P, Wang Z, Shi Y, Wang Y (2013) The world’s largest macroalgal bloom in the Yellow Sea, China: formation and implications. Estuar Coast Shelf Sci 129:2–10
Marine Board (2010) Marine biotechnology: a new vision and strategy for Europe. Marine Board – ESF Position Paper 15. European Science Foundation, Marine Board series, p 94
Marine Board (2017) Marine biotechnology advancing innovation in Europe’s bioeconomy. EMB Policy Brief No. 4, Marine Board series, p 8
Marris E (2006) Drugs from the deep. Nature 443(7114):904–905
Martins A, Vieira H, Gaspar H, Santos S (2014) Marketed marine natural products in the pharmaceutical and cosmeceutical industries: tips for success. Mar Drugs 12:1066–1101
Mateo MA, Renom P, Hemminga MA, Peene J 2001. Measurement of seagrass production using the 13C stable isotope compared with classical O2 and 14C methods. Marine Ecology Progress Series 223:157–165
McClintock JB, Baker BJ (1997) A review of the chemical ecology of Antarctic marine invertebrates. Am Zool 37:329–342
McClintock JB, Baker BJ (2001) Marine chemical ecology. CRC Press, New York, p 610
Molina Grima E et al (2004) Downstream processing of cell mass and products. In: Richmond A (ed) Handbook of microalgal culture: biotechnology and applied phycology. Blackwell Science, Oxford, pp 215–251
Molinski TF, Dalisay DS, Lievens SL, Saludes JP (2009) Drug development from marine natural products. Nat Rev Drug Discov 8:69–85
Muller WE, Schroder HC, Wiens M, Perovic-Ottstadt S, Batel R, Muller IM (2004) Traditional and modern biomedical prospecting: part II – the benefits. Evid Based Complement Alternat Med 1:133–144
Muller-Feuga A (2000) The role of microalgae in aquaculture: situation and trends. J Appl Phycol 12:527–534
Muller-Feuga A (2004) Microalgae for aquaculture. In: RICHMOND, A. (Ed). Handbook of microalgal culture: biotechnology and applied phycology. Oxford: Blackwell Science p 352–364
OECD (2005) OECD Economic Globalisation Indicators, OECD, Paris
OECD (2016) Marine biotechnology: definitions, infrastructures and directions for innovation. Working party on biotechnology, nanotechnology and converging technologies. http://www.marinebiotech.eu/sites/marinebiotech.eu/files/public/DSTI STP BNCT 2016 10.pdf
Oldham P. Hall S, Barnes C, Oldham C, Cutter M, Burns N, Kindness L (2014) Valuing the deep: marine genetic resources in areas beyond national jurisdiction. Department for Environment Food and Rural Affairs (Defra). One World Analytics. Available at http://www.tinyurl.co/valuingthedeep
Paul VJ (1992) In: Eisner T, Meinwald J (eds) Ecological roles of marine natural products. Cornell University Press, London, p 245
Paul S (2015) Trips and biotechnology vs. CBD and biodiversity: is it bioprospecting or bio-piracy of developing countries’ traditional knowledge? Int J Phys Soc Sci 5:603–631
Paul VJ, Puglisi MP (2004) Chemical mediation of interactions among marine organisms. Nat Prod Rep 21:189–209
Pawlik JR (1992) Chemical ecology of the settlement of benthic marine invertebrates. Oceanogr Mar Biol Annu Rev 30:237–335
Pawlik JR (1993) Marine invertebrate chemical defenses. Chem Rev 93:1911–1922
Polidoro BA, Livingstone SR, Carpenter KE, Hutchinson B, Mast RB, Pilcher N, Sadovy DE, Mitcheson Y, Valenti S (2008) Status of the world’s marine species. In: Vié J-C, Hilton-Taylor C, Stuart SN (eds) The 2008 review of The IUCN Red List of Threatened Species. IUCN, Gland
Priac A, Morin-Crini N, Druart C, Gavoille S, Bradu C, Lagarrigue C, Crini G (2017) Alkylphenol and alkylphenolpolyethoxylates in water and wastewater: a review of options for their elimination. Arab J Chem 10:3749–3773
Proksch P (1994) Defensive roles for secondary metabolites from marine sponges and sponge-feeding nudibranchs. Toxicon 32:639–655
Proksch P (1999) Chemical defense in marine ecosystems. In: Wink M (ed) Functions of plant secondary metabolites and their exploitation in biotechnology. Academic Press, Sheffield, pp 134–154
Pulz O, Gross W (2004) Valuable products from biotechnology of microalgae. Appl Microbiol Biotechnol 65:635–648
Rama Rao M, Sridevi KV, Venkatesham U, Prabhaker Rao T, Lee SS, Venkateswarlu Y (2000) Four new sesquiterpenoids from the soft coral Nephthea chabrollii. J Chem Res 5:245–247
Richmond A (2004) Handbook of Microalgal Culture - Biotechnology and Applied Phycology. Blackwell Science Ltd a Blackwell Publishing company. pp 566
Richmond A (1988) Spirulina. In: Borowitzka A., Borowitzka L., editors.1988. Microalgal Biotechnology. Cambridge University Press; United Kingdom. pp 83–121
Roberge M, Berlinck RGS, Xu L, Anderson H, Lim LY, Curman D, Stringer CM, Friend SH, Davies P, Vincent I, Haggarty SJ, Kelly MT, Britton R, Piers E, Andersen RJ (1998) High-throughput assay for G2 checkpoint inhibitors and identification of the structurally novel compound isogranulatimide. Cancer Res 58:5701–5706
Rodolfi L, Chini Zittelli G, Bassi N, Padovani G, Biondi N et al (2009) Microalgae for oil: strain selection, induction of lipid synthesis and outdoor mass cultivation in a low-cost photobioreactor. Biotechnol Bioeng 102:100–112
Saeki BM, Granato AC, Berlinck RGS, Magalhães A, Schefer AB, Ferreira AG, Pinheiro UG, Hajdu E (2002) Two unprecedented dibromotyrosine-derived alkaloids from the Brazilian endemic marine sponge Aplysina caissara. J Nat Prod 65:796–799
Sammarco PW, Coll JC (1988) The chemical ecologyof Alcyonarian corals (Coelenterata: Octocorallia). In: Scheuer PJ (ed) Bioorganic marine chemistry, vol 2. Springer, Berlin, pp 87–116
Sammarco PW, Coll JC (1992) Chemical adaptations in the Octocorallia: evolutionary considerations. Mar Ecol Prog Ser 88:93–104
Sammarco PW, Coll JC, La Barre SC, Willis B (1983) Competitive strategies of soft corals (Coelenterata: Octocorallia). Allelopathic effects on selected scleractinian corals. Coral Reefs 1:173–178
Sammarco PW, Coll JC, La Barre SC (1985) Competitive strategies of soft corals (Coelenterata: Octocorallia). II. Variable defensive response and susceptibility to scleractinian corals. J Exp Mar Biol Ecol 91:199–215
Sammarco PW, La Barre S, Coll JC (1987) Defensive strategies of soft corals (Coelenterata: Octocorallia) of the Great Barrier Reef. III. The relationship between ichthyotoxicity and morphology. Oecologia 74:93–101
Silva JS, Moura MD, Oliveira RAG, Diniz MFFM, Barbosa-Filho JM (2003) Natural products inhibitors of ovarian neoplasia. Phytomedicine 10:221–232
Silva ACR, Lopes PM, Azevedo MMB, Costa DCM, Alviano CS, Alviano DS (2012) Biological activities of α-pinene and β-pinene enantiomers. Molecules 17:6305–6316
Simmons TL, Andrianasolo E, McPhail K, Flatt P, Gerwick WH (2005) Marine natural products as anticancer drugs. Mol Cancer Ther 4:333–342
Slade R (2011) The sustainability of micro-algae biofuels: environmental & economic performance. In: Proceedings of ISAF XIX, Verona
Sperstad SV, Haug T, Blencke HM, Styrvold OB, Li C, Stensvåg K (2011) Antimicrobial peptides from marine invertebrates: challenges and perspectives in marine antimicrobial peptide discovery. Biotechnol Adv 5:519–530
Spolaore P, Joannis-Cassan C, Duran E, Isambert A (2006) Commercial applications of microalgae – review. J Biosci Bioeng 101:8796
Stolz P, Obermayer B (2005) Manufacturing microalgae for skin care. Cosmet. Toiletries 120:99–106
Torres YR, Berlinck RGS, Magalhães A, Schefer AB, Ferreira AG, Hajdu E, Muricy G (2000) Arenosclerins A–C and haliclonacyclamine E, new tetracyclic alkaloids from a Brazilian endemic Haplosclerid sponge Arenosclera brasiliensis. J Nat Prod 63:1098–1105
Torres YR, Berlinck RGS, Nascimento GGF, Fortier SC, Pessoa C, Moraes MO (2002a) Antibacterial activity against resistant bacteria and cytotoxicity of four alkaloid toxins isolated from the marine sponge Arenosclera brasiliensis. Toxicon 40:885
Torres YR, Bugni TS, Berlinck RGS, Ireland CM, Magalhães A, Ferreira AG, Rocha RM (2002b) Sebastianines a novel biologically active pyridoacridine alkaloids from the Brazilian ascidian Cystodytes. J Org Chem 67:5429–5432
Tripathi U et al (1999) Production of astaxanthin in Haematococcus pluvialis cultured in various media. Bioresour Technol 68:197–199
Vasconcelos MTSD, Leal MFC (2001) Seasonal variability in the kinetics of Cu, Pb, Cd and Hg accumulation by macroalgae. Mar Chem 74:65–85
Wahle CM (1980) Detection, pursuit and overgrowth of tropical gorgonians by milleporid hydrocorals: Perseus and Medusa revisited. Science 209:689–691
Wallace CC, Babcock RC, Harrison PL, Oliver JK, Willis BL (1986) Sex on the reef: mass spawning of corals. Oceanus 29:38–42
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Morgado, F., Vieira, L.R. (2020). Marine Bioprospecting to Improve Knowledge of the Biological Sciences and Industrial Processes. In: Leal Filho, W., Azul, A., Brandli, L., Özuyar, P., Wall, T. (eds) Affordable and Clean Energy. Encyclopedia of the UN Sustainable Development Goals. Springer, Cham. https://doi.org/10.1007/978-3-319-71057-0_117-1
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