Inhibitor of Apoptosis (IAP) Proteins, Fig. 1

Schematic representation of IAP proteins. The number of residues in each IAP as well as the functional motifs that they contain is shown. NAIP, survivin, BRUCE, ILP2, and ML-IAP are shown in this figure, but are not discussed in detail. In addition to DIAP1 and DIAP2, orthologues of survivin and BRUCE are also encoded in the genome of fruit flies (Drosophila melanogaster). Domain abbreviations used are as follows: BIR baculovirus IAP repeat, UBA ubiquitin-associated, CARD caspase-associated recruitment domain, UBC ubiquitin-conjugation, NOD nucleotide-binding oligomerization domain, LRR leucine-rich repeats