Encyclopedia of Signaling Molecules

2018 Edition
| Editors: Sangdun Choi

Interferon Regulatory Factor

  • Masaud Shah
  • Sangdun ChoiEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-67199-4_101496


 IRF1: Interferon regulatory factor 1; MAR

 IRF2: Interferon regulatory factor 2

 IRF3: Interferon regulatory factor 3

 IRF4: Interferon regulatory factor 4; Lymphocyte-specific IRF (LSIRF); PU.1-interaction partner (PIP); ICSBP in adult T-cell leukemia cell lines or activated T cells (ICSAT); Multiple myeloma oncogene 1(MUM1); SHEP8; NF-EM5

 IRF5: Interferon regulatory factor 5; Systemic lupus erythematosus, susceptibility to, 10 (SLEB10)

 IRF6: Interferon regulatory factor 6; Van Der Woude Syndrome (VWS1); OFC6; PPS1

 IRF7: Interferon regulatory factor 7; IMD39

 IRF8: Interferon regulatory factor 8; IFN-consensus-sequence-binding protein (ICSBP)

 IRF9: Interferon regulatory factor 9; IFN-stimulated gene factor 3, Gamma (ISGF3G); ISGF3 P48 Subunit (P48)

Historical Background

Interferon regulatory factors (IRFs) are a family of type-I interferon transcriptional regulators, consisting of nine members (IRF1-9). The first IRF was identified in 1998 (Miyamoto et al. 1988), and...

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This work was supported by the National Research Foundation of Korea (NRF-2015R1A2A2A09001059).


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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Department of Molecular Science and TechnologyAjou UniversitySuwonKorea