Pleural sarcoidosis; Pleural tuberculosis; Pleurisy
Granulomatous pleuritis is a descriptive term referring to granulomatous inflammation of the pleura. Causes of granulomatous pleuritis include infectious and noninfectious etiologies. Tuberculosis is the most common infectious cause. However, infection from nontuberculous mycobacteria, fungi, (e.g., Cryptococcus neoformans), parasites, and other bacteria (e.g., actinomyces) may also cause this pattern of injury. Causes of noninfectious granulomatous pleuritis include sarcoidosis, rheumatoid nodules in rheumatoid arthritis, and iatrogenic, causes among others.
Worldwide, tuberculous pleuritis is the most common etiology of granulomatous pleuritis. Pleural tuberculosis is the second most common type of extrapulmonary tuberculosis (after tuberculous lymphadenitis). It accounts for 4% of tuberculosis cases in the United States and greater than 10% of cases in Spain (Baumann et...
References and Further Reading
- Baba, K., Dyrhol-Riise, A. M., Sviland, L., Langeland, N., Hoosen, A. A., Wiker, H. G., et al. (2008). Rapid and specific diagnosis of tuberculous pleuritis with immunohistochemistry by detecting Mycobacterium tuberculosis complex specific antigen MPT64 in patients from a HIV endemic area. Applied Immunohistochemistry & Molecular Morphology, 16(6), 554–561.CrossRefGoogle Scholar
- Ulrichs, T., Lefmann, M., Reich, M., Morawietz, L., Roth, A., Brinkmann, V., et al. (2005). Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue. Journal of Pathology, 205(5), 633–640.CrossRefPubMedGoogle Scholar