Synonyms
Chordoid chordoma
Definition
Chordoma is a slowly growing malignant tumor of uncertain histogenesis thought to be derived from the embryonic notochord. It has a predilection for the cervical and lumbosacral spine. Although rarely, chordoma has been described to occur in the mediastinum as discrete masses with no apparent relationship with the adjacent vertebral bones (Ahrendt and Wesselhoeft 1992; Suster and Moran 1995). Presenting symptoms are related to local compression or invasion, mostly difficulty swallowing, chest pain, and shortness of breath.
Clinical Features
Incidence
Not applicable due to the limited number of reported cases.
Age
Most published cases have been seen in late adulthood. Exceptional cases are seen in pediatric subjects.
Sex
No sex predilection.
Site
Mediastinal chordomas arise in the posterior sector of the mediastinum.
Treatment
Complete surgical excision is the treatment of choice for resectable tumor. Postoperative radiotherapy has been administered...
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Further Reading
Ahrendt, M. N., & Wesselhoeft, C. W. (1992). Chordoma presenting as a posterior mediastinal mass in a pediatric patient [Case Reports Review]. Journal of Pediatric Surgery, 27(12), 1515–1518.
Suster, S., & Moran, C. A. (1995). Chordomas of the mediastinum: Clinicopathologic, immunohistochemical, and ultrastructural study of six cases presenting as posterior mediastinal masses [Case Reports]. Human Pathology, 26(12), 1354–1362.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this entry
Cite this entry
Falconieri, G. (2018). Chordoma, Mediastinal. In: Allen, T.C., Suster, S. (eds) Pathology of the Pleura and Mediastinum. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-66796-6_11
Download citation
DOI: https://doi.org/10.1007/978-3-319-66796-6_11
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-66795-9
Online ISBN: 978-3-319-66796-6
eBook Packages: MedicineReference Module Medicine