Encyclopedia of Sexuality and Gender

Living Edition
| Editors: Amy D. Lykins

Pheromones and Social Chemo Signals

Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-59531-3_8-1
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Introduction and Definitions

The term pheromone was introduced in 1959 by Karlson and Lüscher (1959), who described pheromones as “active substances which are secreted to the outside by an individual and received by a second individual of the same species, in which they release a specific reaction, for example, a definite behavior or a developmental process”(Karlson & Lüscher, 1959). It was later suggested to further narrow the definition to counter-ambiguities and a generalization in the use of the term pheromone: a signal must be useful for both sides, the transmitter and the receiver (Meredith, 2001). This condition is often difficult to fulfill, and this definition has not yet been adopted everywhere. The term pheromone is therefore elastic in its meaning. Pheromones are divided into different functional groups: primers, signalers, modulators, and releasers (Wysocki & Preti, 2004). The primers and signalers have the weakest effect and indicate, for instance, the presence of...

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References

  1. Bendas, J., Hummel, T., & Croy, I. (2018). Olfactory function relates to sexual experience in adults. Archives of Sexual Behavior, 47(5), 1333–1339.PubMedCrossRefGoogle Scholar
  2. Brämerson, A., Johansson, L., Ek, L., Nordin, S., & Bende, M. (2004). Prevalence of olfactory dysfunction: the Skövde population-based study. The Laryngoscope, 114(4), 733–737.PubMedCrossRefGoogle Scholar
  3. Brennan, P. A., & Zufall, F. (2006). Pheromonal communication in vertebrates. Nature, 444(7117), 308–315.PubMedCrossRefGoogle Scholar
  4. Cavazzana, A., Röhrborn, A., Garthus-Niegel, S., Larsson, M., Hummel, T., Croy, I., et al. (2018). Sensory-specific impairment among older people. An investigation using both sensory thresholds and subjective measures across the five senses. PLoS ONE, 13(8), e0202969.PubMedPubMedCentralCrossRefGoogle Scholar
  5. Croy, I., Bojanowski, V., & Hummel, T. (2013). Men without a sense of smell exhibit a strongly reduced number of sexual relationships, women exhibit reduced partnership security – A reanalysis of previously published data. Biological Psychology, 92(2), 292–294.PubMedCrossRefGoogle Scholar
  6. Croy, I., & Hummel, T. (2017). Olfaction as a marker for depression. Journal of Neurology, 264(4), 631–638.PubMedCrossRefGoogle Scholar
  7. Croy, I., Nordin, S., & Hummel, T. (2014). Olfactory disorders and quality of life – An updated review. Chemical Senses, 39(3), 185–194.PubMedCrossRefGoogle Scholar
  8. Croy, I., Springborn, M., Lötsch, J., Johnston, A. N., & Hummel, T. (2011). Agreeable smellers and sensitive neurotics–correlations among personality traits and sensory thresholds. PLoS ONE, 6(4), e18701.PubMedPubMedCentralCrossRefGoogle Scholar
  9. de Groot, J. H., Smeets, M. A., Kaldewaij, A., Duijndam, M. J., & Semin, G. R. (2012). Chemosignals communicate human emotions. Psychological Science, 23(11), 1417–1424.PubMedCrossRefGoogle Scholar
  10. Ferdenzi, C., Schaal, B., & Roberts, S. C. (2010). Family scents: Developmental changes in the perception of kin body odor? Journal of Chemical Ecology, 36(8), 847–854.PubMedCrossRefGoogle Scholar
  11. Ferstl, R., Eggert, F., Westphal, E., Zavazava, N., & Muller-Ruchholtz, W. (1992). MHC-related odors in humans. In Chemical signals in vertebrates 6 (pp. 205–211). New York: Springer.CrossRefGoogle Scholar
  12. Garver-Apgar, C. E., Gangestad, S. W., Thornhill, R., Miller, R. D., & Olp, J. J. (2006). Major histocompatibility complex alleles, sexual responsivity, and unfaithfulness in romantic couples. Psychological Science, 17(10), 830–835.PubMedCrossRefGoogle Scholar
  13. Gelstein, S., Yeshurun, Y., Rozenkrantz, L., Shushan, S., Frumin, I., Roth, Y., et al. (2011). Human tears contain a chemosignal. Science, 331(6014), 226–230.PubMedCrossRefGoogle Scholar
  14. Grammer, K., Fink, B., & Neave, N. (2005). Human pheromones and sexual attraction. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 118(2), 135–142.PubMedCrossRefGoogle Scholar
  15. Gudziol, V., Wolff-Stephan, S., Aschenbrenner, K., Joraschky, P., & Hummel, T. (2009). PSYCHOLOGY: Depression resulting from olfactory dysfunction is associated with reduced sexual appetite – A cross-Sectional cohort study. The Journal of Sexual Medicine, 6(7), 1924–1929.PubMedCrossRefGoogle Scholar
  16. Havlicek, J., & Lenochova, P. (2006). The effect of meat consumption on body odor attractiveness. Chemical Senses, 31(8), 747–752.PubMedCrossRefGoogle Scholar
  17. Havlicek, J., & Roberts, S. C. (2009). MHC-correlated mate choice in humans: A review. Psychoneuroendocrinology, 34(4), 497–512.PubMedCrossRefGoogle Scholar
  18. Havlicek, J., Roberts, S. C., & Flegr, J. (2005). Women’s preference for dominant male odour: Effects of menstrual cycle and relationship status. Biology Letters, 1(3), 256–259.PubMedPubMedCentralCrossRefGoogle Scholar
  19. Hoffmann, H. (2019). The aroma of arousal: Effects of menstrual cycle phase and women’s sexual arousal state on men’s responsiveness to women’s body odor. Biological Psychology, 142, 54–61.PubMedCrossRefGoogle Scholar
  20. Jacob, S., & McClintock, M. K. (2000). Psychological state and mood effects of steroidal chemosignals in women and men. Hormones and Behavior, 37(1), 57–78.PubMedCrossRefGoogle Scholar
  21. Kaitz, M., Good, A., Rokem, A., & Eidelman, A. I. (1987). Mothers’ recognition of their newborns by olfactory cues. Developmental Psychobiology, 20(6), 587–591.PubMedCrossRefGoogle Scholar
  22. Karlson, P., & Lüscher, M. (1959). ‘Pheromones’: a new term for a class of biologically active substances. Nature, 183(4653), 55.PubMedCrossRefGoogle Scholar
  23. Keller, A., & Dolores, M. (2013). Hidden consequences of olfactory dysfunction: a patient report series. BMC Ear, Nose and Throat Disorders 13(1), 8.Google Scholar
  24. Keller, A., Zhuang, H., Chi, Q., Vosshall, L. B., & Matsunami, H. (2007). Genetic variation in a human odorant receptor alters odour perception. Nature, 449(7161), 468–472.PubMedCrossRefGoogle Scholar
  25. Kromer, J., Hummel, T., Pietrowski, D., Giani, A. S., Sauter, J., Ehninger, G., et al. (2016). Influence of HLA on human partnership and sexual satisfaction. Scientific Reports, 6, 32550.PubMedPubMedCentralCrossRefGoogle Scholar
  26. Landis, B. N., Konnerth, C. G., & Hummel, T. (2004). A study on the frequency of olfactory dysfunction. The Laryngoscope, 114(10), 1764–1769.PubMedCrossRefGoogle Scholar
  27. Liberles, S. D., & Buck, L. B. (2006). A second class of chemosensory receptors in the olfactory epithelium. Nature, 442(7103), 645–650.PubMedCrossRefGoogle Scholar
  28. Meredith, M. (2001). Human vomeronasal organ function: A critical review of best and worst cases. Chemical Senses, 26(4), 433–445.PubMedCrossRefGoogle Scholar
  29. Merkonidis, C., Grosse, F., Ninh, T., Hummel, C., Haehner, A., & Hummel, T. (2015). Characteristics of chemosensory disorders – Results from a survey. European Archives of Oto-Rhino-Laryngology, 272(6), 1403–1416.PubMedCrossRefGoogle Scholar
  30. Miller, S. L., & Maner, J. K. (2010). Scent of a woman: Men’s testosterone responses to olfactory ovulation cues. Psychological Science, 21(2), 276–283.PubMedCrossRefGoogle Scholar
  31. Murr, J., Hummel, T., Ritschel, G., & Croy, I. (2018). Individual significance of olfaction: A comparison between normosmic and dysosmic people. Psychosomatics, 59(3), 283–292.PubMedCrossRefGoogle Scholar
  32. Mutic, S., Parma, V., Brünner, Y. F., & Freiherr, J. (2015). You smell dangerous: communicating fight responses through human chemosignals of aggression. Chemical Senses, 41(1), 35–43.PubMedCrossRefGoogle Scholar
  33. Olsson, M. J., Lundstrom, J. N., Kimball, B. A., Gordon, A. R., Karshikoff, B., Hosseini, N., et al. (2014). The scent of disease: Human body odor contains an early chemosensory cue of sickness. Psychological Science, 25(3), 817–823.PubMedCrossRefGoogle Scholar
  34. Porter, R. H., Cernoch, J. M., & Balogh, R. D. (1985). Odor signatures and kin recognition. Physiology & Behavior, 34(3), 445–448.CrossRefGoogle Scholar
  35. Prehn-Kristensen, A., Wiesner, C., Bergmann, T. O., Wolff, S., Jansen, O., Mehdorn, H. M., et al. (2009). Induction of empathy by the smell of anxiety. PLoS One, 4(6), e5987.PubMedPubMedCentralCrossRefGoogle Scholar
  36. Preti, G., Wysocki, C. J., Barnhart, K. T., Sondheimer, S. J., & Leyden, J. J. (2003). Male axillary extracts contain pheromones that affect pulsatile secretion of luteinizing hormone and mood in women recipients. Biology of Reproduction, 68(6), 2107–2113.PubMedCrossRefGoogle Scholar
  37. Rodriguez, I., Greer, C. A., Mok, M. Y., & Mombaerts, P. (2000). A putative pheromone receptor gene expressed in human olfactory mucosa. Nature Genetics, 26(1), 18–19.PubMedCrossRefGoogle Scholar
  38. Savic, I., & Berglund, H. (2010). Androstenol–A steroid derived odor activates the hypothalamus in women. PLoS ONE, 5(2), e8651.PubMedPubMedCentralCrossRefGoogle Scholar
  39. Savic, I., Heden-Blomqvist, E., & Berglund, H. (2009). Pheromone signal transduction in humans: What can be learned from olfactory loss. Human Brain Mapping, 30(9), 3057–3065.PubMedCrossRefGoogle Scholar
  40. Schäfer, L., Mehler, L., Hähner, A., Walliczek, U., Hummel, T., & Croy, I. (2018). Sexual desire after olfactory loss: Quantitative and qualitative reports of patients with smell disorders. Physiology & Behavior, 201, 64.CrossRefGoogle Scholar
  41. Shinohara, K., Morofushi, M., Funabashi, T., & Kimura, F. (2001). Axillary pheromones modulate pulsatile LH secretion in humans. Neuroreport, 12(5), 893–895.PubMedCrossRefGoogle Scholar
  42. Shinohara, K., Morofushi, M., Funabashi, T., Mitsushima, D., & Kimura, F. (2000). Effects of 5α-androst-16-en-3α-ol on the pulsatile secretion of luteinizing hormone in human females. Chemical Senses, 25(4), 465–467.PubMedCrossRefGoogle Scholar
  43. Sorokowska, A., Pietrowski, D., Schäfer, L., Kromer, J., Schmidt, A. H., Sauter, J., et al. (2018). Human leukocyte antigen similarity decreases partners’ and strangers’ body odor attractiveness for women not using hormonal contraception. Hormones and Behavior, 106, 144–149.PubMedCrossRefGoogle Scholar
  44. Sorokowska, A., Sorokowski, P., & Szmajke, A. (2012). Does personality smell? Accuracy of personality assessments based on body odour. European Journal of Personality, 26(5), 496–503.CrossRefGoogle Scholar
  45. Stevenson, R. J. (2009). An initial evaluation of the functions of human olfaction. Chemical Senses, 35(1), 3–20.PubMedCrossRefGoogle Scholar
  46. Trotier, D. (2011). Vomeronasal organ and human pheromones. European Annals of Otorhinolaryngology, Head and Neck Diseases, 128(4), 184–190.PubMedCrossRefGoogle Scholar
  47. Trotier, D., Eloit, C., Wassef, M., Talmain, G., Bensimon, J. L., Doving, K. B., et al. (2000). The vomeronasal cavity in adult humans. Chemical Senses, 25(4), 369–380.PubMedCrossRefGoogle Scholar
  48. Varendi, H., & Porter, R. H. (2001). Breast odour as the only maternal stimulus elicits crawling towards the odour source. Acta Paediatrica, 90(4), 372–375.PubMedCrossRefGoogle Scholar
  49. Wedekind, C., Seebeck, T., Bettens, F., & Paepke, A. J. (1995). MHC-dependent mate preferences in humans. Proceedings of the Biological Sciences, 260(1359), 245–249.CrossRefGoogle Scholar
  50. Weisfeld, G. E., Czilli, T., Phillips, K. A., Gall, J. A., & Lichtman, C. M. (2003). Possible olfaction-based mechanisms in human kin recognition and inbreeding avoidance. Journal of Experimental Child Psychology, 85(3), 279–295.PubMedCrossRefGoogle Scholar
  51. Witt, M., & Hummel, T. (2006). Vomeronasal versus olfactory epithelium: Is there a cellular basis for human vomeronasal perception? International Review of Cytology, 248, 209–259.PubMedCrossRefGoogle Scholar
  52. Witt, M., & Meredith, M. (2014). The human vomeronasal organ. In A. Welge-Luessen & T. H. Stuttgart (Eds.), Management of smell and taste disorders. Stuttgart, Germany: Georg Thieme Verlag.Google Scholar
  53. Wysocki, C. J., & Preti, G. (2004). Facts, fallacies, fears, and frustrations with human pheromones. The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology, 281(1), 1201–1211.PubMedCrossRefGoogle Scholar
  54. Wysocki, C. J., Yamazaki, K., Curran, M., Wysocki, L. M., & Beauchamp, G. K. (2004). Mice (Mus musculus) lacking a vomeronasal organ can discriminate MHC-determined odortypes. Hormones and Behavior, 46(3), 241–246.PubMedCrossRefGoogle Scholar
  55. Yang, H., Shi, P., Zhang, Y. P., & Zhang, J. (2005). Composition and evolution of the V2r vomeronasal receptor gene repertoire in mice and rats. Genomics, 86(3), 306–315.PubMedCrossRefGoogle Scholar
  56. Young, J. M., Massa, H. F., Hsu, L., & Trask, B. J. (2010). Extreme variability among mammalian V1R gene families. Genome Research, 20(1), 10–18.PubMedPubMedCentralCrossRefGoogle Scholar

Authors and Affiliations

  1. 1.Department of Psychotherapy and Psychosomatic Medicine, Medizinische Fakultät Carl Gustav CarusTechnische Universität Dresden, Dresden (TUD)DresdenGermany