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Phenytoin

  • Reference work entry
  • First Online:
Encyclopedia of Clinical Neuropsychology

  • 8 Accesses

Generic Name

Phenytoin

Brand Name

Dilantin, Dilantin 125, and Phenytek

Class

Anticonvulsants, hydantoins; antidysrhythmics, Ib

Proposed Mechanism(s) of Action

Sodium channel blocker (blocks voltage-gated dependent sodium channels)

Indication

Generalized tonic-clonic and complex partial seizures and prevention of seizures concurrent with or following neurosurgery

Off-Label Use

No common off-label use

Side Effects

Serious

Agranulocytosis, leukopenia, and Stevens-Johnson syndrome

Common

Ataxia, nystagmus, impaired motor coordination, confusion, insomnia, headaches, tremor, dystonia, rash, nausea, vomiting, and liver dysfunction

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References and Readings

  • Physicians’ desk reference (71st ed.) (2017). Montvale: Thomson PDR.

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  • Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.

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Author information

Authors and Affiliations

  1. Socorro Mental Health, Presbyterian Medical Services, Socorro, NM, USA

    John C. Courtney

  2. Mercy Family Center, Metarie, LA, USA

    Cristy Akins

  3. College of Psychology, Nova Southeastern University, Fort Lauderdale, FL, USA

    Efrain Antonio Gonzalez

  4. Utah State University, Logan, UT, USA

    Efrain Antonio Gonzalez

Authors
  1. John C. Courtney
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  2. Cristy Akins
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  3. Efrain Antonio Gonzalez
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Corresponding author

Correspondence to Efrain Antonio Gonzalez .

Editor information

Editors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Richmond, VA, USA

    Jeffrey S. Kreutzer

  2. Kessler Foundation, Pleasant Valley Way, West Orange, NJ, USA

    John DeLuca

  3. Independent Practice, Wynnewood, PA, USA

    Bruce Caplan

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© 2018 Springer International Publishing AG, part of Springer Nature

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Cite this entry

Courtney, J.C., Akins, C., Gonzalez, E.A. (2018). Phenytoin. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1694

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