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Chlordiazepoxide

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Generic Name

Chlordiazepoxide

Brand Name

Librium and Librax

Class

Antianxiety agents, anxiolytics, and benzodiazepines

Proposed Mechanism(s) of Action

Chlordiazepoxide binds to the GABA-A ligand-gated chloride channel complex and, thereby, enhances the inhibitory effects of GABA.

Indication

Anxiety disorders, symptoms of anxiety, preoperative apprehension and anxiety, and withdrawal from acute alcoholism

Side Effects

Serious

Respiratory depression, kidney dysfunction, and liver disorders (rare)

Common

Sedation, dizziness, depression, forgetfulness, confusion, and hyperexcitability

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References and Readings

  • Physicians’ desk reference (71st ed.). (2017). Montvale: Thomson PDR.

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  • Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.

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Correspondence to Efrain Antonio Gonzalez .

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© 2018 Springer International Publishing AG, part of Springer Nature

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Cite this entry

Courtney, J.C., Gonzalez, E.A. (2018). Chlordiazepoxide. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_1636

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