Skip to main content

Wada Test

  • Living reference work entry
  • First Online:
Encyclopedia of Clinical Neuropsychology
  • 46 Accesses

Definition

The Wada test is named after a neurologist Juhn A. Wada and is also known as the “intracarotid sodium amobarbital procedure” (ISAP) (Wada 1949). This test evaluates the effects of successive unilateral hemianesthesia of the first cerebral hemisphere and then the second, the purpose of which is to determine which of the cerebral hemispheres is predominately responsible for essential cognitive, memory, and language processes. Wada was developed and established by Dr. Wada as a standard test for the presurgical evaluation of patients with intractable epilepsy prior to surgical ablation. The main purpose of this test is to ensure that the nonoperative cerebral hemisphere can sustain adequate language and memory function following elective ablative surgery on the contralateral hemisphere.

ISAP includes the injection of an anesthetic, usually 75–200 mg of sodium amobarbital, into the right or left internal carotid artery supplying either of the cerebral hemispheres. Within seconds...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Baxendale, S. A. B. (2009). The Wada test. Current Opinion in Neurology, 22(2), 185–189.

    Article  PubMed  Google Scholar 

  • Chiu, A. H., Bynevelt, M., Lawn, N., Lee, G., & Singh, T. P. (2015). Propofol as a substitute for Amobarbital in Wada testing. Journal of Clinical Neuroscience, 22(11), 1830–1832.

    Article  PubMed  Google Scholar 

  • Dupont, S. (2015). Imaging memory and predicting postoperative memory decline in temporal lobe epilepsy: Insights from functional imaging. Revue Neurologique, 171(3), 307–314.

    Article  PubMed  Google Scholar 

  • Suarez, R. O., Taimouri, V., Boyer, K., Vega, C., Rotenberg, A., Madsen, J. R., Loddenkemper, T., Duffy, F. H., Prabhu, S. P., & Warfield, S. K. (2014). Passive fMRI mapping of language function for paediatric epilepsy surgical planning: Validation using Wada, ECS, and FMAER. Epilepsy Research, 108(10), 1874–1888.

    Article  PubMed  PubMed Central  Google Scholar 

  • Van Emde Boas, W., & Juhn, A. (1999). Wada and the sodium amytal test in the first (and last?) 50 years. Journal of the History of the Neurosciences, 8(3), 286–292.

    Article  PubMed  Google Scholar 

  • Wada, J. (1949). A new method for the determination of the side of cerebral speech dominance. A preliminary report of the intra-carotid injection of sodium amytal in man (Vol. 14, pp. 221–222). Tokyo: Igaku to Seibutsugaki.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jacinta McElligott .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing AG

About this entry

Cite this entry

McElligott, J. (2016). Wada Test. In: Kreutzer, J., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-56782-2_83-3

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-56782-2_83-3

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-56782-2

  • Online ISBN: 978-3-319-56782-2

  • eBook Packages: Springer Reference Behavioral Science and PsychologyReference Module Humanities and Social SciencesReference Module Business, Economics and Social Sciences

Publish with us

Policies and ethics