Encyclopedia of Clinical Neuropsychology

Living Edition
| Editors: Jeffrey Kreutzer, John DeLuca, Bruce Caplan

Venous Thrombosis

  • Elliot Roth
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-56782-2_2212-2



Venous thrombosis occurs when a blood clot forms in a vein.

Current Knowledge

Venous stasis, vessel wall injury, and hypercoagulable state, collectively known as Virchow’s Triad, contribute to the development of venous thrombosis. Deep vein thrombosis (DVT) typically begins in the deep veins of the calf, and about 20% will propagate proximally. A small proportion of proximal DVTs may embolize to the pulmonary circulation or elsewhere, which, in some cases, can cause death from massive pulmonary embolism (PE). DVT is common in hospitalized patients, and incidence estimates are 30–90% among people with recent stroke. DVT is associated with many other conditions that limit mobility or increase hypercoaguability, including spinal cord injury, traumatic brain injury, cancer, and prolonged bedrest for other illnesses. Recent research has demonstrated the effectiveness of prophylactic anticoagulation and mobilization...

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  1. Kearon, C., Akl, E. A., Ornelas, J., Blaivas, A., Jimenez, D., et al. (2016). Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report. Chest, 149, 315–352.CrossRefGoogle Scholar
  2. Liu, D., Peterson, E., Dooner, J., Baerlocher, M., Zypchen, L., Gagnon, J., et al. (2015). Diagnosis and management of iliofemoral deep vein thrombosis: Clinical practice guideline. Canadian Medical Association Journal, 187, 1288–1296.CrossRefGoogle Scholar
  3. Snow, V., Qaseem, A., Barry, P., et al. (2007). Management of venous thromboembolism: A clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. Annals of Internal Medicine, 146, 204–210.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Feinberg School of Medicine, Physical Medicine and RehabilitationNorthwestern UniversityChicagoUSA