Encyclopedia of Clinical Neuropsychology

Living Edition
| Editors: Jeffrey Kreutzer, John DeLuca, Bruce Caplan

Diffusion-Weighted Imaging

  • Elliot Roth
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-56782-2_2174-2




Diffusion-weighted imaging (DWI) produces magnetic resonance images of biological tissues weighted with the local characteristics of water diffusion. Acquisition of images using regular MRI utilizes the behavior of protons in water to generate contrasting appearances between features of the different tissues being studied. This ability to produce contrast across tissues is called “weighting” and is stimulated by imposing a strong magnetic field which makes the protons in water molecules move differently depending on their specific tissue environment. In certain clinical situations, this can generate contrast between an area of pathology and the surrounding healthy tissue. In diffusion-weighted imaging, the specific magnetic field used causes the protons to behave in a particular manner that varies depending on the characteristics of the tissue. Each section of the image that is produced has a unique apparent diffusion coefficient (ADC), and each section can then...

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© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Feinberg School of Medicine, Physical Medicine and RehabilitationNorthwestern UniversityChicagoUSA