Encyclopedia of Clinical Neuropsychology

Living Edition
| Editors: Jeffrey Kreutzer, John DeLuca, Bruce Caplan


  • Cristy Akins
  • Efrain Antonio Gonzalez
Living reference work entry

Latest version View entry history

DOI: https://doi.org/10.1007/978-3-319-56782-2_1648-3

Generic Name


Brand Name

Focalin, Focalin XR


ADHD agents; stimulants

Proposed Mechanism(s) of Action

Dexmethylphenidate facilitates the release and blocks the reuptake of both norepinephrine and dopamine.


Attention-deficit hyperactivity disorder.

Off-Label Use

Narcolepsy and depression (treatment-resistant).

Side Effects


Psychotic episodes, seizures, neuroleptic malignant syndrome, hypomania, mania, and possible suicidal ideation.


Insomnia, irritability, tremor, anxiety, and tics (exacerbation, dizziness, anorexia, blurred vision).

References and Reading

  1. Physicians’ Desk Reference (71st ed.). (2017). Montvale: Thomson PDR.Google Scholar
  2. Stahl, S. M. (2007). Essential psychopharmacology: The prescriber’s guide (2nd ed.). New York: Cambridge University Press.Google Scholar

Additional Information

  1. Free Drug Online and PDA Software: www.epocrates.com.
  2. Free Drug Online and PDA Software: www.medscape.com.

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Mercy Family CenterMetarieUSA
  2. 2.College of PsychologyNova Southeastern UniversityFort LauderdaleUSA