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Anti-glomerular Basement Membrane Disease

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Glomerulonephritis

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Abstract

Anti-GBM antibody disease is a rare autoimmune disorder characterized by circulating autoantibodies directed against specific antigenic targets within the glomerular and alveolar basement membranes. It is extremely uncommon in children, and typically presents with acute renal failure caused by a rapidly progressive glomerulonephritis that is commonly associated with crescentic changes.

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Author information

Authors and Affiliations

  1. Pediatric Nephrology and Hypertension, Mount Sinai Hospital, New York, NY, USA

    Corinne Benchimol

Authors
  1. Corinne Benchimol
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Correspondence to Corinne Benchimol .

Editor information

Editors and Affiliations

  1. Department of Pediatrics, NYU Langone Medical Center, New York, NY, USA

    Howard Trachtman

  2. Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA

    Leal C. Herlitz

  3. Nephrology, University of Illinois at Chicago College of Medicine, Chicago, IL, USA

    Edgar V. Lerma

  4. Renal, Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

    Jonathan J. Hogan

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Benchimol, C. (2019). Anti-glomerular Basement Membrane Disease. In: Trachtman, H., Herlitz, L., Lerma, E., Hogan, J. (eds) Glomerulonephritis. Springer, Cham. https://doi.org/10.1007/978-3-319-49379-4_19

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  • DOI: https://doi.org/10.1007/978-3-319-49379-4_19

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-49378-7

  • Online ISBN: 978-3-319-49379-4

  • eBook Packages: MedicineReference Module Medicine

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