Synonyms
Definition
A class of G-protein-coupled receptors whose endogenous agonist is the neurotransmitter dopamine.
Introduction
The neurotransmitter dopamine plays a significant role in influencing locomotor activity, attention, motivation, positive reinforcement, cognitive functions, and hormonal regulation as it interacts with a family of G-protein-coupled receptors. The main dopamine systems arise from the midbrain and the hypothalamus. Dysregulation of dopamine is suggested to be at the root of a number of major neuropsychiatric disorders (Daly and Salloway 1994).
The Dopamine System
The cells of the midbrain that involve dopamine can be divided into the three groups: A8 in the retrorubral field, A9 in the substantia nigra, and A10 in the ventral tegmental area. Neurons found in the retrorubral field and the substantia nigra ascend to the striatum to form sections of the extrapyramidal system, a network that governs and coordinates involuntary movement. Neurons in the...
Keywords
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References
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Turco, R. (2017). Dopamine Receptor. In: Vonk, J., Shackelford, T. (eds) Encyclopedia of Animal Cognition and Behavior. Springer, Cham. https://doi.org/10.1007/978-3-319-47829-6_1256-1
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DOI: https://doi.org/10.1007/978-3-319-47829-6_1256-1
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