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The Endocrine Regulation of Blood Pressure

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Principles of Endocrinology and Hormone Action

Part of the book series: Endocrinology ((ENDOCR))

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Abstract

Blood pressure is a vital parameter controlled by very complex mechanisms mainly involving neuronal and endocrine effectors. The sympathetic-adrenal system (SAS) and the renin-angiotensin-aldosterone system (RAAS), besides paracrine mechanisms in the vessel wall, are the main players of these complex networks that permit the maintenance of blood pressure, sufficient for the perfusion of organs and tissues. These systems regulate the cardiac pump, the circulating volume, and the peripheral resistances. They are the targets of almost all the drugs prescribed to hypertensive patients.

In addition to these major neurohormonal systems, many other factors can modulate blood pressure participating in the control of the blood volume or the peripheral resistances. These factors include, among the others, natriuretic peptides, dopamine, nitric oxide, endothelin-1, vasopressin, and cortisol.

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Authors and Affiliations

  1. Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence, Florence, Italy

    Massimo Mannelli

  2. Clinica dell’Ipertensione Arteriosa – Department of Medicine, Internal Medicine 4 DIME, University of Padova, Padova, Italy

    Gian Paolo Rossi & Paul-Emmanuel Vanderriele

  3. Endocrinology Unit, Department of Medicine and Geriatrics, Azienda Ospedaliera-Universitaria di Careggi, Careggi Hospital, Florence, Italy

    Gabriele Parenti

Authors
  1. Massimo Mannelli
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  2. Gian Paolo Rossi
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  3. Paul-Emmanuel Vanderriele
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  4. Gabriele Parenti
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Correspondence to Massimo Mannelli .

Editor information

Editors and Affiliations

  1. Magna Graecia University, Catanzaro, Italy

    Antonino Belfiore

  2. Icahn School of Medicine at Mt. Sinai, New York, New York, USA

    Derek LeRoith

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Mannelli, M., Rossi, G.P., Vanderriele, PE., Parenti, G. (2018). The Endocrine Regulation of Blood Pressure. In: Belfiore, A., LeRoith, D. (eds) Principles of Endocrinology and Hormone Action. Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-319-44675-2_23

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  • DOI: https://doi.org/10.1007/978-3-319-44675-2_23

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-44674-5

  • Online ISBN: 978-3-319-44675-2

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