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Epidemiology, Risk Factors, and Histopathology in Testicular Cancer

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Urologic Oncology
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Abstract

Though germ cell tumor of the testis (GCT) is rare in general, it is the most common cancer of man aged 20–45 years. It is more common in Europe and the United States with an increase in northern parts. Since the introduction of platinum-based chemotherapy, cure rates are excellent, also in metastasized patients.

The most important and validated risk factors for GCT are history of a contralateral tumor, cryptorchidism, genetic predisposition, infertility, or height.

Accurate pathological diagnostic is mandatory for a correct staging and therapy recommendation according to the current WHO and TNM classification. Metastasized patients should be risk stratified by the IGCCCG classification which influences the therapy. Therefore, this chapter will provide information concerning the basic pathologic work-up and information about different types of GCT.

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Correspondence to Tim Nestler or Hans Schmelz .

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Nestler, T., Schmelz, H. (2019). Epidemiology, Risk Factors, and Histopathology in Testicular Cancer. In: Merseburger, A., Burger, M. (eds) Urologic Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-42623-5_1

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  • DOI: https://doi.org/10.1007/978-3-319-42623-5_1

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