Pathology of the Gastrointestinal Tract

2017 Edition
| Editors: Fátima Carneiro, Paula Chaves, Arzu Ensari

Uremic Gastropathy

  • Elisabete RiosEmail author
  • Francisco Ferro de Beça
Reference work entry


Uremic gastritis


Uremic gastropathy is a term commonly used to describe the upper gastrointestinal signs and histopathologic changes associated with uremia, secondary to renal failure.

The clinical spectrum of upper gastrointestinal disorders in the uremic patients varies widely, since it might be influenced by several factors, such as the severity of renal function impairment, the stress level of the patients, and the assigned treatment. Gastrointestinal (GI) bleeding and dyspeptic symptoms, such as anorexia, vomiting, heartburn, and postprandial fullness, are common in these patients, although they may have no symptoms (Nardone et al. 2005). Uremic fetor (ammonia or urine-like odor to the breath) also may be present. Endoscopic and histological lesions are more frequent in symptomatic patients but may also be present in asymptomatic subjects (Khazaei et al. 2008). Hemorrhagic gastropathy is the most prevalent lesion, particularly in patients receiving chronic...

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References and Further Reading

  1. Day, D. W., Jass, J. R., Price, A. B., Shepherd, N. A., Sloan, J. M., Talbot, I. C., Warren, B. F., Williams, G. T., et al. (2003). Morson and Dawson’s gastrointestinal pathology (4th ed.). Malden: Blackwell Science.CrossRefGoogle Scholar
  2. Khazaei, M. R., Imanieh, M. H., & Hosseini Al-Hashemi, G. (2008). Gastrointestinal evaluation in pediatric kidney transplantation candidates. Iranian Journal of Kidney Diseases, 2, 40–45.PubMedGoogle Scholar
  3. Nardone, G., Rocco, A., Fiorillo, M., Del Pezzo, M., Autiero, G., Cuomo, R., Sarnelli, G., Lambiase, A., Budillon, G., & Cianciaruso, B. (2005). Gastroduodenal lesions and Helicobacter pylori infection in dyspeptic patients with and without chronic renal failure. Helicobacter, 10, 53–58.CrossRefGoogle Scholar
  4. Sotoudehmanesh, R., Ali Asgari, A., Ansari, R., & Nouraie, M. (2003). Endoscopic findings in end-stage renal disease. Endoscopy, 35, 502–505.CrossRefGoogle Scholar
  5. Walker, W. A., Durie, P. R., Kleinman, R., & Walker-Smith, J. A. (2004). Pediatric gastrointestinal disease, pathophysiology, diagnosis and management (4th ed.). Philadelphia: BC Decker.Google Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Elisabete Rios
    • 1
    • 2
    • 3
    Email author
  • Francisco Ferro de Beça
    • 1
    • 2
    • 3
  1. 1.Department of PathologyCentro Hospitalar de São JoãoPortoPortugal
  2. 2.Faculty of Medicine of the University of PortoPortoPortugal
  3. 3.IPATIMUP – Institute of Pathology and Molecular Immunology of the University of PortoPortoPortugal