Collagen Vascular Disorders, Esophagus
Synonyms
Collagen diseases, esophagus; Connective tissue diseases, esophagus
Definition
Collagen vascular disorders include some multisystem diseases of unknown etiology associated with autoimmunity.
In Collagen vascular disorders, the involvement of the esophagus varies widely accordingly to the particular disease.
In these diseases the esophagus involvement is more important in scleroderma (see Scleroderma, esophageal), dermatomyositis/polymyositis (DM/PM), mixed connective tissue disease (MCTD), and Sjogren syndrome (SS).
In rheumatoid arthritis (RA) esophagus disease (esophagitis, ulcers, candidal esophagitis) may occur in consequence of the use of drugs like nonsteroidal anti-inflammatory drugs, steroids, and immunosuppressors. Esophagus involvement is not frequent in SLE (less than 5%), but some patients complain of dysphagia as a result of dysmotility; many of these patients also present Raynaud’s phenomenon. In SLE dysphagia may also be caused by gastroesophageal reflux disease...
References and Further Reading
- Carsons, S. (2009). Sjogren’s syndrome. In G. S. Firestein, R. C. Budd, E. D. Harris, I. B. McInnes, S. Ruddy, & J. S. Sergent (Eds.), Kelley’s textbook of rheumatology (pp. 1149–1168). Philadelphia: Saunders Elsevier.Google Scholar
- Doma, S., Wo, J. M., & Parkman, H. P. (2012). Esophageal Involvement in Systemic diseases. In J. E. Richter & D. O. Castell (Eds.), The esophagus (pp. 367–382). Chichester: Wiley-Blackwell.Google Scholar
- Merieux, P., Verity, A., Clements, P. J., & Paulus, H. E. (1983). Esophageal abnormalities and dysphagia in Polymyositis and Dermatomyositis. Arthritis and Rheumatism, 26, 961–968.PubMedGoogle Scholar
- Nagaraju, K., & Lundberg, I. E. (2009). Inflammatory diseases of muscle and other myopathies. In G. S. Firestein, R. C. Budd, E. D. Harris, I. B. McInnes, S. Ruddy, & J. S. Sergent (Eds.), Kelley’s textbook of rheumatology (pp. 1149–1168). Philadelphia: Saunders Elsevier.Google Scholar
- Sheldon, J. (2004). Laboratory testing in autoimmune rheumatic diseases. Best Practice & Research. Clinical Rheumatology, 18(3), 249–269.Google Scholar