Pathology of the Gastrointestinal Tract

2017 Edition
| Editors: Fátima Carneiro, Paula Chaves, Arzu Ensari

Intestinal Pseudo-Obstruction

  • Maria SotiropoulouEmail author
Reference work entry


Paralytic ileus


Intestinal pseudo-obstruction describes a syndrome in which the clinical presentation of mechanical obstruction occurs in the absence of any obvious reason. This can affect the colon or small bowel and based on clinical presentation is divided into acute and chronic. Acute colonic pseudo-obstruction appears with symptoms, signs, and radiologic findings similar to those of mechanical intestinal obstruction. Ogilvie, who described in 1948 two cases of massive colonic dilatation without mechanical obstacle and with malignant infiltration of the celiac axis and semilunar ganglion, concluded that the condition is an imbalance in the autonomic nerve supply. The clinical picture of the patients with pseudo-obstruction, despite etiology, is the same with that observed in intestinal obstruction.

Acute colonic pseudo-obstruction usually develops in elderly, hospitalized patients with a variety of problems such as neurological diseases, cardiac failure, chronic...

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References and Further Reading

  1. Amiot, A., Cazals-Hatem, D., Joly, F., et al. (2009). The role of immunohistochemistry in idiopathic Chronic Intestinal Pseudo-Obstruction (CIPO): A case-control study. The American Journal of Surgical Pathology, 33(5), 749–758.CrossRefGoogle Scholar
  2. Antonucci, A., Fronzoni, L., Cogliadro, L., et al. (2008). Chronic intestinal pseudo-obstruction. World Journal of Gastroenterology, 14(19), 2953–2961.CrossRefGoogle Scholar
  3. Day, D. W., & Morson, B. C. (2003). Morson and Dawson’s gastrointestinal pathology (4th ed., pp. 451–464). Malden: Blackwell.CrossRefGoogle Scholar
  4. Saunders, M. D., & Kimmey, M. B. (2005). Systemic review: Acute colonic pseudo-obstruction. Alimentary Pharmacology & Therapeutics, 22, 917–925.CrossRefGoogle Scholar
  5. Stranghellini, V., Cogliandro, R. F., De Giorgio, R., et al. (2005). Natural history of chronic idiopathic intestinal pseudo-obstruction in adults. A single centre study. Clinical Gastroenterology and Hepatology, 3, 449–458.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Department of PathologyAlexandra HospitalAthens, AtticaGreece