Inflammatory Cloacogenic Polyp
Polypoid variant of solitary rectal ulcer
The inflammatory cloacogenic polyp is a benign polypoid lesion of the anal transitional zone (ATZ). It is included into the mucosal prolapse syndrome with other conditions, with which it shares some histological and pathogenic features, such as the solitary rectal ulcer, the colitis cystic profunda, the inflammatory myoglandular polyp, and the cap polyp and polyposis.
Cloacogenic polyp is considered as a result of nonspecific regenerative changes of the anorectal mucosa caused by recurrent prolapse, or mucosal injury. It could result from mucosal ischemia and regenerative changes secondary to anal mucosal prolapse, caused by constipation, chronic disorders of defecation, and inappropriate puborectalis muscle contractions. The same type of changes can also be seen in other situations with mucosal prolapse, such as colonic intussusceptions, prolapsed colostomies, prolapsed hemorrhoids, prolapsing polyps in association with...