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Polyurethane Resins

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Kanerva’s Occupational Dermatology

Abstract

Polyurethane (PU) products are formed by reacting a di- or polyfunctional isocyanate with a polyol in the presence of suitable catalysts and additives. The most feared PU-associated occupational disease is isocyanate-induced asthma, and preventive measures in work places have been focused to decrease respiratory exposure to isocyanates. Isocyanates in PU hardeners are also a relatively important cause of occupational allergic contact dermatitis, at least in some countries. The typical location is hands and face. Occupational allergic contact dermatitis is most commonly induced by diphenylmethane diisocyanate (MDI)-based products. Chemicals in PU resins are also skin irritants. Isocyanate-induced contact urticaria is a very rare disease.

When patch testing workers exposed to polyurethane chemicals, it is advisable to test with their own work material in addition to the commercially available patch-test preparations of diisocyanates. A second reading on day seven is advisable since positive reactions may appear late. Positive reactions to methylenedianiline (MDA) (also known as diaminodiphenylmethane) should be taken into account as it is an important marker for MDI sensitivity.

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Correspondence to Kristiina Aalto-Korte or Malin Engfeldt .

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Aalto-Korte, K., Engfeldt, M., Estlander, T., Jolanki, R. (2018). Polyurethane Resins. In: John, S., Johansen, J., Rustemeyer, T., Elsner, P., Maibach, H. (eds) Kanerva’s Occupational Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-40221-5_53-2

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  • DOI: https://doi.org/10.1007/978-3-319-40221-5_53-2

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