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Epoxy Resins

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Kanerva’s Occupational Dermatology

Abstract

Epoxy resin allergy is a major cause of occupational contact dermatitis, particularly in the construction, painting, aircraft, and electronics manufacturing industries. Allergic contact dermatitis to epoxy resin systems may be caused by resins, hardeners, or reactive diluents. Diglycidyl ether of bisphenol A (DGEBA) is the major cause of allergic contact dermatitis from epoxy resin systems; however patch testing solely with DGEBA will miss many cases of epoxy allergy. Patch testing with workers’ own samples is necessary. Allergic contact dermatitis to epoxy chemicals may present with dermatitis on the hands, arms, neck, and face. Epoxy chemicals may induce airborne allergic contact dermatitis, particularly from volatile reactive diluents and hardeners. Rubber gloves offer poor protection against epoxy chemicals. Gloves made of laminated, multilayered plastic or thick reusable nitrile are recommended. Crucial factors for the development of allergic contact dermatitis from epoxy resin systems include the type of exposure, size of contaminated skin area, frequency and duration of contact, concentration of epoxy chemical, and use of personal protective equipment. If a worker develops allergic contact dermatitis to epoxy chemicals, consider the factors which led to sensitization. It may be that other workers are also at risk.

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References

  • Aalto-Korte K, Alanko K, Henriks-Eckerman ML et al (2003) Allergic contact dermatitis from bisphenol A in PVC gloves. Contact Dermatitis 49:202–205

    Article  CAS  PubMed  Google Scholar 

  • Aalto-Korte K, Jungewelter S, Henriks-Eckerman ML et al (2009) Contact allergy to epoxy (meth)acrylates. Contact Dermatitis 61:9–21

    Article  CAS  PubMed  Google Scholar 

  • Aalto-Korte K, Pesonen M, Henriks-Eckerman ML (2013) Occupational contact allergy to the epoxy methacrylate 2,2-bis[4-(2-methacryloxyethoxy)phenyl] propane in an anaerobic glue. Contact Dermatitis 68:314–315

    Article  PubMed  Google Scholar 

  • Aalto-Korte K, Suuronen K, Kuuliala O, Henriks-Eckerman ML, Jolanki R (2014) Screening occupational contact allergy to bisphenol F epoxy resin. Contact Dermatitis 71:138–144

    Article  CAS  PubMed  Google Scholar 

  • Aalto-Korte K, Kuuliala O, Henriks-Eckerman ML, Suuronen K (2015a) Contact allergy to reactive diluents and related aliphatic epoxy resins. Contact Dermatitis 72:387–397

    Article  CAS  PubMed  Google Scholar 

  • Aalto-Korte K, Pesonen M, Suuronen K (2015b) Occupational allergic contact dermatitis caused by epoxy chemicals: occupations, sensitizing products, and diagnosis. Contact Dermatitis 73:336–342

    Article  CAS  PubMed  Google Scholar 

  • Allen H, Kaidbey K (1979) Persistent photosensitivity following occupational exposure to epoxy resin. Arch Dermatol 115:1307–1310

    Article  CAS  PubMed  Google Scholar 

  • Amado A, Taylor JS (2008) Contact dermatitis in the bowling pro shop. Dermatitis 19:334–338

    PubMed  Google Scholar 

  • Ancona-Alayon A, Jimenez-Castilla JL, Gomez-Alvarez EM (1976) Dermatitis from epoxy resin and formaldehyde in shampoo packers. Contact Dermatitis 2:356

    Article  CAS  PubMed  Google Scholar 

  • Andersen KE, Christensen LP, Volund A et al (2009) Association between positive patch tests to epoxy resin and fragrance mix 1 ingredients. Contact Dermatitis 60:155–157

    Article  PubMed  Google Scholar 

  • Anderson TF, Messick VB (1985) Vinyl ester resins. In: Pritchard G (ed) Developments in reinforced plastics, vol 1. Elsevier, London, pp 29–58

    Google Scholar 

  • Angelini G, Foti C, Rigano L, Vena GA (1995) 3-Dimethylaminopropylamine: a key substance in contact allergy to cocamidopropylbetaine? Contact Dermatitis 32:96–99

    Article  CAS  PubMed  Google Scholar 

  • Angelini G, Rigano L, Foti C, Grandolfo M et al (1996) Occupational sensitization to epoxy resin and reactive diluents in marble workers. Contact Dermatitis 35:11–16

    Article  CAS  PubMed  Google Scholar 

  • Anveden Berglind I, Lind M-L, Lidén C (2012) Epoxy pipe relining – an emerging contact allergy risk to workers. Contact Dermatitis 67:59–65

    Article  PubMed  CAS  Google Scholar 

  • Ayala F, Lembo G, Balato N et al (1990) The use of laboratory methods in contact dermatitis induced by composite materials. Contact Dermatitis 22:262–266, erratum 23:384

    Article  CAS  PubMed  Google Scholar 

  • Bachurzewska B, Borucka I (1986) Gefãssläsionen bei Eisenbahnarbeiterinnen, die mit Epoxidharzen in Berührung kommen. Dermatosen 34:77–79

    CAS  Google Scholar 

  • Back B, Saarinen L (1986) Free amines in epoxy hardeners and in workplace air (in Finnish with English summary). Työterveyslaitoksen tutkimuksia 1:31–36

    Google Scholar 

  • Bangsgaard N, Thyssen JP, Menne T, Andersen KE, Mortz CG, Paulsen E, Sommerlund M, Veien NK, Laurberg G, Kaaber K, Thormann J, Andersen BL, Danielsen A, Avnstorp C, Kristensen B, Kristensen O, Vissing S, Nielsen NH, Johansen JD (2012) Contact allergy to epoxy resin: risk occupations and consequences. Contact Dermatitis 67:73–77

    Article  PubMed  Google Scholar 

  • Bauer RS (1985) Epoxy resins. In: Tess RW, Poehlein GW (eds) Applied polymer science, 2nd edn. American Chemical Society, Washington, DC, pp 931–961

    Chapter  Google Scholar 

  • Beck MH, King CM (1983) Allergic contact dermatitis to epichlorhydrin in a solvent cement. Contact Dermatitis 9:315

    Article  CAS  PubMed  Google Scholar 

  • Bergquist-Karlsson A (1985) Contact allergy to glycidyl trimethyl ammonium chloride. Contact Dermatitis 12:61–62

    Article  Google Scholar 

  • Björkner B (1981) Sensitization capacity of acrylated prepolymers in ultraviolet curing inks tested in the guinea pig. Acta Derm Venereol 61:7–10

    PubMed  Google Scholar 

  • Björkner B (1984) Sensitizing capacity of ultraviolet curable acrylic compounds. Doctoral dissertation, University of Lund, Sweden

    Google Scholar 

  • Björkner B, Dahlquist I, Fregert S, Magnusson B (1980) Contact allergy to epoxide 8, an epoxy reactive diluent. Contact Dermatitis 6:156

    Article  PubMed  Google Scholar 

  • Boom BW, van Driel LMJ (1985) Allergic contact dermatitis to epoxy resin in infusion sets of an insulin pump. Contact Dermatitis 12:280

    Article  CAS  PubMed  Google Scholar 

  • Bowen RL (1962) Dental filling material comprising vinyl silane treated fused silica and a binder consisting of the reaction product of bis phenol and glycidyl acrylate. US Patent 3:066,112

    Google Scholar 

  • Breuer K, Uter W, Geier J (2015) Epidemiological data on airborne contact dermatitis – results of the IVDK. Contact Dermatitis 73:239–247

    Article  CAS  PubMed  Google Scholar 

  • Brooke R, Beck MH (1998) Contact allergy to 2,4,6-tris(dimethylaminomethyl) phenol. Contact Dermatitis 38:284–285

    Article  CAS  PubMed  Google Scholar 

  • Bruze M, Zimerson E (1985) Contact allergy to dihydroxydiphenyl methanes (bisphenol F). Dermatosen 33:216–220

    CAS  Google Scholar 

  • Bruze M, Trulson L, Bendsoe N (1992) Patch testing with ultrasonic bath extracts. Am J. Contact Dermatitis 3:133–137

    Google Scholar 

  • Bruze M, Edenholm M, Engstrom K, Svensson G (1996) Occupational dermatoses in a Swedish aircraft plant. Contact Dermatitis 34:336–340

    Article  CAS  PubMed  Google Scholar 

  • Buisson H, Vaillant L, Lasfargues G, Muller C, Lorette G (1991) Occupational contact dermatitis from trans-methyl-3(4-methoxyphenyl) glycidate. Contact Dermatitis 25:262–263

    Article  CAS  PubMed  Google Scholar 

  • Burrows D, Fregert S, Campbell H, Trulsson L (1984) Contact dermatitis from the epoxy resins tetraglycidyl-4.4′ –methylene dianiline and o-diglycidyl phthalate in composite material. Contact Dermatitis 11:80–82

    Article  CAS  PubMed  Google Scholar 

  • Cahill J, Keegel T, Dharmage S et al (2005) Prognosis of contact dermatitis in epoxy resin workers. Contact Dermatitis 52:147–153

    Article  CAS  PubMed  Google Scholar 

  • Calnan CD (1958) Studies in contact dermatitis. Trans St Johns Hosp Dermatol Soc 40:12–19

    Google Scholar 

  • Calnan CD (1967) Studies in contact dermatitis XX. Active sensitization. Trans St Johns Hosp Dermatol Soc 53:128–134

    CAS  PubMed  Google Scholar 

  • Calnan CD (1975) Epoxy resin dermatitis. J Soc Occup Med 25:123–126

    Article  CAS  PubMed  Google Scholar 

  • Camarasa JG, Serra-Baldrich E (1989) Isophoronediamine (IPD) dermatitis in Spain. Contact Dermatitis 20:382

    Article  CAS  PubMed  Google Scholar 

  • Canelas MM, Gonçalo M, Figueiredo A (2010) Contact allergy to epoxy reins- a 10 year study. Contact Dermatitis 62:55

    Article  CAS  PubMed  Google Scholar 

  • Cao LY, Sood A, Taylor JS (2009) Hand/face/neck localized patterns: sticky problems–resins. Dermatology Clinics 27:227–249

    Article  CAS  Google Scholar 

  • Coman G, Zinsmeister C, Norris P (2015) Occupational contact dermatitis: workers’ compensation patch test results of Portland, Oregon, 2005-2014. Dermatitis 26:276–282

    Article  CAS  PubMed  Google Scholar 

  • Conde-Salazar L, Romero L, Guimaraens D, Harto A (1982) Contact dermatitis in an oil painter. Contact Dermatitis 8:209–210

    Article  CAS  PubMed  Google Scholar 

  • Conde-Salazar L, Gorospe M, Guimaraens D (1993) A new source of sensitivity to epoxy resin. Contact Dermatitis 28:292

    Article  CAS  PubMed  Google Scholar 

  • Conde-Salazar L, Conzalez de Domingo MA, Guimaraens D (1994) Sensitization to epoxy resin system in special flooring workers. Contact Dermatitis 31:157–160

    Article  CAS  PubMed  Google Scholar 

  • Dahlquist I, Fregert S, Persson K, Trulsson (1979) Exopy resin in a one-pick glue. Contact Dermatitis 5:189–190

    Article  CAS  PubMed  Google Scholar 

  • Dahlquist I, Fregert S (1979) Allergic contact dermatitis from volatile epoxy hardeners and reactive diluents. Contact Dermatitis 5:406–407

    Article  CAS  PubMed  Google Scholar 

  • Dannaker CJ (1988) Allergic sensitization to a non-bisphenol A epoxy of the cycloaliphatic class. J Occup Med 30:641–643

    Article  CAS  PubMed  Google Scholar 

  • Darr-Foit S, Geier J, Elsner P, Schliemann S (2016) Occupational contact allergy to the epoxy resin hardener 2-methylpentane-1,5-diamine. Contact Dermatitis 74:115–116

    Article  PubMed  Google Scholar 

  • De Groot AC (1994) Occupational contact allergy to alphanaphthyl glycidyl ether. Contact Dermatitis 30:253–254

    Article  PubMed  Google Scholar 

  • Dickel H, Kuss O, Schmidt A, Diepgen TL (2002) Occupational relevance of positive standard patch-test results in employed persons with an initial report of an occupational skin disease. Int Arch Occup Environ Health 75:423–434

    Article  CAS  PubMed  Google Scholar 

  • Dooms-Goossens A, Boden G, Auoaix F, Bruze M (1993) Allergic contact dermatitis from adhesive plaster due to colophony and epoxy resin. Contact Dermatitis 28:120–121

    Article  CAS  PubMed  Google Scholar 

  • Dooms-Goossens A, Bruze M, Buysse L et al (1995) Contact allergy to allyl glycidyl ether present as an impurity in 3-g1ycidyloxypropoxyltrimethoxysilane. A fixing additive in silicone and polyurethane resins. Contact Dermatitis 33:17–19

    Article  CAS  PubMed  Google Scholar 

  • Edman B (1988) Computerized patch data in contact allergy. Doctoral dissertation, Lund University, Sweden

    Google Scholar 

  • Eedy DJ (1996) Carbon-fibre-induced airborne irritant contact dermatitis. Contact Dermatitis 35:362–363

    Article  CAS  PubMed  Google Scholar 

  • Ellis B (ed) (1993) Chemistry and technology of epoxy resins. Blackie Academic and Professional, Glasgow

    Google Scholar 

  • Emmett EA, Kominsky JR (1977) Allergic contact dermatitis from ultraviolet cured ink. J Occup Med 19:113–115

    Article  CAS  PubMed  Google Scholar 

  • Engstrom B, Henriks-Eckerman M-L (1988) Welding and paint (in Finnish). Tyoterveyslaitos (Työolot 68.), Helsinki

    Google Scholar 

  • Estlander T (1990) Occupational skin disease in Finland: observations made during 1974-88 at the Institute of Occupational Health, Helsinki. Doctoral dissertation, Acta Derm Veneral Suppl 155

    Google Scholar 

  • Estlander T, Jolanki R, Kanerva L (1986) Occupational dermatitis to 2,3-epoxypropyl trimethyl ammonium chloride. Contact Dermatitis 14:49–52

    Article  CAS  PubMed  Google Scholar 

  • Fillenham G, Lidén C, Anveden Berglind I (2012) Skin exposure to epoxy in the pipe relining trade – an observational study. Contact Dermatitis 67:66–72

    Article  PubMed  Google Scholar 

  • Fischer T, Fregert S, Thulin I, Trulsson L (1987) Unhardened epoxy resin in tool handles. Contact Dermatitis 16:45

    Article  CAS  PubMed  Google Scholar 

  • Foti C, Bonamonte D, Antelmi A, Nettis E, Cassano N, Vena GA, Angelini G (2010) Airborne allergy to isophoronediamine and epoxy resin. Immunopharmacology & Immunotoxicology 32:528–529

    Article  Google Scholar 

  • Freeman K, Warin AP (1984) Contact dermatitis due to bisphenol A in semi-synthetic waxes. Contact Dermatitis 11:259–260

    Article  CAS  PubMed  Google Scholar 

  • Fregert S (1975) Occupational dermatitis in a 10-year material. Contact Dermatitis 1:96–107

    Article  CAS  PubMed  Google Scholar 

  • Fregert S (1981a) Epoxy dermatitis from the non-working environment. Br J Dermatol 105(Suppl 21):63–64

    Article  PubMed  Google Scholar 

  • Fregert S (1981b) Manual of contact dermatitis, 2nd edn. Munksgaard, Copenhagen

    Google Scholar 

  • Fregert S (1988) Physicochemical methods for detection of contact allergens. Dermatol Clin 6:97–104

    CAS  PubMed  Google Scholar 

  • Fregert S, Rorsman H (1964) Allergens in epoxy resins. Acta Allergol 19:296–299

    Article  CAS  PubMed  Google Scholar 

  • Gailhofer G, Ludvan M (1989) Zur Wertigkeit positive Epikutantestreaktionen auf 4,4′-Diamino-diphenylmethan. Dermatosen 37:17–22

    Google Scholar 

  • Gardiner TH, Waechter JM Jr, Wiedow MH, Solomon WA (1992) Glycidyloxy compounds used in epoxy resin systems: a toxicology review. Regul Toxicol Pharmacol 15:S1

    Article  CAS  PubMed  Google Scholar 

  • Gaul LE (1960) Sensitivity to bisphenol a. Arch Dermatol 82:1003

    Article  CAS  PubMed  Google Scholar 

  • Geier J, Lessmann H, Hillen U et al (2004) An attempt to improve diagnostics of contact allergy due to epoxy resin systems. First results of the multicentre study EPOX 2002. Contact Dermatitis 51:263–272

    Article  CAS  PubMed  Google Scholar 

  • Geier J, Lessmann H, Uter W, Schnuch A (2007) Are concomitant patch test reactions to epoxy resin and BIS-GMA indicative of cross-reactivity? Contact Dermatitis 57:376–380

    Article  CAS  PubMed  Google Scholar 

  • Geier J, Lessmann H, Reinecke S (2009) Occupational airborne allergic contact dermatitis in a concrete repair worker. Contact Dermatitis 60:50–51

    Article  CAS  PubMed  Google Scholar 

  • Geier J, Krautheim A, Uter W et al (2011) Occupational contact allergy in the building trade in Germany: influence of preventive measures and changing exposure. In Arch Occup Environ Health 84:403–411

    Article  CAS  Google Scholar 

  • Geier J, Krautheim A, Fuchs T (2012) Airborne allergic contact dermatitis in a parquet fitter. Contact Dermatitis 67:106–108

    Article  PubMed  Google Scholar 

  • Geier J, Lessmann H, Hillen U et al (2015a) Sensitization to reactive diluents and hardeners in epoxy resin systems. IVDK data 2002-2011. Part I: reaction frequencies. Contact Dermatitis 74:94–101

    Article  PubMed  CAS  Google Scholar 

  • Geier J, Lessmann H, Hillen U et al (2015b) Sensitization to reactive diluents and hardeners in epoxy resin systems. IVDK data 2002-2011. Part II: concomitant reactions. Contact Dermatitis 74:94–101

    Article  PubMed  CAS  Google Scholar 

  • Geukens S, Goossens A (2001) Occupational contact allergy to (meth)acrylates. Contact Dermatitis 44:153–159

    Article  CAS  PubMed  Google Scholar 

  • Gonçalo S, Gonçalo M, Matos J, Marçues C (1992) Contact dermatitis from a billiard cue. Contact Dermatitis 26:263

    Article  PubMed  Google Scholar 

  • Goodson A, Powell D (2014) Contact dermatitis to epoxy resins presenting as conjunctivitis. Dermatitis 25:34

    Article  PubMed  Google Scholar 

  • Göransson K (1977). Allergic contact dermatitis to an epoxy hardener: dodecenyl-succinic anhydride. Contact Dermatitis 3(5):277–278.

    Article  PubMed  Google Scholar 

  • Göransson K, Andersson R, Andersson G, Marklund S, Anderson K, Ostbye P, Zingmark P-A (1984) An outbreak of occupational photodermatosis of the face in a factory in northern Sweden. In: Berglund B, Lindvall T, Sundell J (eds) Indoor air, vol 3. Swedish Council for Building research, Stockholm, pp 367–375

    Google Scholar 

  • Gordon PM, McLelland J (1998) Contact sensitivity to Ancamine® 2280 (p-aminocyclohexylamine) following a change in work practice. Contact Dermatitis 38:54

    Article  CAS  PubMed  Google Scholar 

  • Goulden V, Wilkinson SM (1996) Occupational allergic contact dermatitis from epoxy resin on clipboard. Contact Dermatitis 35:62–263

    Article  Google Scholar 

  • Guimaraens D, Gonzalez MA, Del Rio E, Conde-Salazar L (1994) Occupational airborne allergiC contact dermatitis in the national mint and fiscal-stamp factory. Contact Dermatitis 30:172–173

    Article  CAS  PubMed  Google Scholar 

  • Guin JD (2005) Airborne contact dermatitis from a polymercaptan hardener in a finished epoxy resin. Contact Dermatitis 52:45

    Article  PubMed  Google Scholar 

  • Guin JD, Work W (1995) Plastics: epoxy resins. In: Guin JD (ed) Practical contact dermatitis. A handbook for the practitioner. McGraw-Hill, New York, pp 433–446

    Google Scholar 

  • Hagvall L, Niklasson IB, Rudbäck J, O'Boyle NM, Niklasson E, Luthman K, Karlberg AT (2016) Assessment of cross-reactivity of new less sensitizing epoxy resin monomers in epoxy resin-allergic individuals. Contact Dermatitis 75:144–150

    Article  CAS  PubMed  Google Scholar 

  • Handley J, Burrows D (1994) Dermatitis from hexavalent chromate in the accelerator of an epoxy sealant (PR1422) used in the aircraft industry. Contact Dermatitis 30:193–196

    Article  CAS  PubMed  Google Scholar 

  • Hannu T, Frilander H, Kauppi P et al (2009) IgE-mediated occupational asthma from epoxy resin. Int Arch Allergy Immunol 148:41–44

    Article  PubMed  Google Scholar 

  • Hansson C (1994) Determination of monomers in epoxy resin hardened at elevated temperature. Contact Dermatitis 31:333–334

    Article  CAS  PubMed  Google Scholar 

  • Hausen BM, Krohn K, Budianto E (1990) Contact allergy due to colophony. VII. Sensitizing studies with oxidation products of abietic and related acids. Contact Dermatitis 23:352–358

    Article  CAS  PubMed  Google Scholar 

  • Haussmann J, Pratt M, Linett L, Zimmerman D (2005) Allergic contact dermatitis and eosinophilia in association with a hemodialysis cannula. Am J Kidney Dis 45:e23–e26

    Article  PubMed  Google Scholar 

  • Helaskoski E, Kuuliala O, Aalto-Korte K (2009) Occupational contact urticaria caused by cyclic acid anhydrides. Contact Dermatitis 60:214–221

    Article  CAS  PubMed  Google Scholar 

  • Henriks-Eckerman M-L, Kanerva L (1997) Product analysis of acrylic resins compared to information given in material safety data sheets. Contact Dermatitis 36:164–165

    Article  CAS  PubMed  Google Scholar 

  • Henriks-Eckerman M-L, Laijoki T (1986a) Aliphatic polyamines and epoxy oligomers in cold cured epoxy products (in finnish with english summary). Työterveyslaitoksen tutkimuksia 4:37–40. summary p 69

    Google Scholar 

  • Henriks-Eckerman M-L, Laijoki T (1986b) Glycidyl ethers in epoxy resin products (in Finnish with English summary). Työterveyslaitoksen tutkimuksia 4:41–46. Summary p 70

    Google Scholar 

  • Henriks-Eckerman M-L, Mäkelä EA (2015) A new penetration tst method: protection efficiency of glove and clothing materials against diphenylmethane diisocyanate (MDI). Ann Occup Hyg 59:221–231

    Article  CAS  PubMed  Google Scholar 

  • Henriks-Eckerman M-L, Mäkelä EA, Suuronen K (2015) Testing penetration of epoxy resin and diamine hardeners through protective glove and clothing materials. Ann Occup Hyg 59:1034–1043

    Article  CAS  PubMed  Google Scholar 

  • Henriksen HR, Petersen HJS (1986) Better gloves against epoxy products and other chemicals: protective clothing against chemicals (In Danish with English summary). Arbejdsmiljöfondet (Arbejdsmiljöfondets forskningsrapporter), Copenhagen

    Google Scholar 

  • Heskel NS (1988) Epoxy resin dermatitis in a stained glass window maker. Contact Dermatitis 18:182–183

    Article  CAS  PubMed  Google Scholar 

  • Hillen U, Jappe U, Frosch PJ et al (2006) Late reactions to the patch-test preparations para-phenylenediamine and epoxy resin: a prospective multicentre investigation of the German contact dermatitis research group. Br J Dermatol 154:665–670

    CAS  PubMed  Google Scholar 

  • Hine CH, Kodama JK, Anderson HH et al (1958) The toxicology of epoxy resins. Arch. Ind Health 17:129–144

    CAS  Google Scholar 

  • Holness DL (1992) Outbreak of allergic contact dermatitis caused by epoxy resin in a gluing and swaging operation. Am J Contact Dermat 3:150–154

    Article  Google Scholar 

  • Holness DL, Nethercott JR (1989) Occupational contact dermatitis due to epoxy resin in a fiberglass binder. J Occup Med 31:87–89

    CAS  PubMed  Google Scholar 

  • Holness DL, Nethercott JR (1992) Results of testing with epoxy resin in an occupational health clinic population. Am J Contact Dermat 3:169–174

    Article  Google Scholar 

  • Holness DL, Nethercott JR (1993) The performance of specialized collections of bisphenol A epoxy system components in the evaluation of workers in an occupational health clinic population. Contact Dermatitis 28:216–219

    Article  CAS  PubMed  Google Scholar 

  • Houle MC, Holness DL, Dekoven J, Skotnicki S (2012) Additive value of patch testing custom epoxy materials from the workplace at the occupational disease specialty clinic in Toronto. Dermatitis 23:214–219

    Article  CAS  PubMed  Google Scholar 

  • Ippen H, Mathies V (1970) Die “protrahierte Verätzung” (unter besonderer Berlücksichtigung der Hautschäden durch Epoxide und Propansulton). Berufsdermatosen 18:144–165

    CAS  PubMed  Google Scholar 

  • Isaksson M, Moller H, Ponten A (2008) Occupational allergic contact dermatitis from epoxy resin in a golf club repairman. Dermatitis 19:E30–E32

    PubMed  Google Scholar 

  • Janda R (1987) Synthetic resins. In: Gerhartz W, Yamamoto YS, Kaudy L, Pfefferkorn R, Rounsaville JF (eds) Ullmann’s encyclopedia of industrial chemistry, 5th completely revised edition, vol A8. VCH Verlagsgesellschaft, Weinheim, pp 277–284

    Google Scholar 

  • Jappe U, Geier J, Hausen BM (2005) Contact vitiligo following a strong patch test to triglycidyl-p-aminphenol in an aircraft industry worker: case report and review of the literature. Contact Dermatitis 53:89–92

    Article  CAS  PubMed  Google Scholar 

  • Jensen CD, Andersen KE (2003) Two cases of occupational allergic contact dermatitis from a cycloaliphatic epoxy resin in a neat oil: a case report. Environ Health 2:3

    Article  PubMed  PubMed Central  Google Scholar 

  • Jolanki R (1991) Occupational skin diseases from epoxy compounds. Epoxy resin compounds, epoxy acrylates and 2,3-epoxypropyl trimethyl ammonium chloride (doctoral dissertation). Acta Derm Venerol Suppl 159:1–80

    CAS  Google Scholar 

  • Jolanki R (1994) Epoxy dermatitis. Occup Med 9:97–112

    CAS  PubMed  Google Scholar 

  • Jolanki R, Estlander T, Kanerva L (1987a) Contact allergy to an epoxy reactive diluent: 1,4-butanediol diglycidyl ether. Contact Dermatitis 16:87–92

    Article  CAS  PubMed  Google Scholar 

  • Jolanki R, Estlander T, Kanerva L (1987b) Occupational contact dermatitis and contact urticaria caused by epoxy resins. Acta Derm Venereol Suppl (Stockh) 134:90–94

    CAS  Google Scholar 

  • Jolanki R, Estlander T, Henriks-Eckerman M-L et al (1988) Skin protection and sensitizing epoxy compounds in electron microscopy laboratories. In: Mansdorf SZ, Sager R, Nielsen AP (eds) Performance of protective clothing: second symposium. American Society for Testing and Materials (ASTM STP 989), Philadelphia, pp 389–395

    Google Scholar 

  • Jolanki R, Sysilampi M-L, Kanerva L, Estlander T (1989) Contact allergy to cycloaliphatic epoxy resins. In: Frosch PI, Dooms-Goossens A, Lachapelle J-M, Rycroft RJG, Scheper RJ (eds) Current topics in contact dermatitis. Springer, Berlin/Heidelberg/New York, pp 360–367

    Chapter  Google Scholar 

  • Jolanki R, Kanerva L, Estlander T et al (1990) Occupational dermatoses from epoxy resin compounds. Contact Dermatitis 23:172–183

    Article  CAS  PubMed  Google Scholar 

  • Jolanki R, Kanerva L, Estlander T, Tarvainen K (1994a) Concomitact sensitization to triglycidyl isocyanurate. Diaminodiphenylmethane and 2-hydroxyethyl methacrylates from silk-screen printing coatings in the manufacture of circuit boards. Contact Dermatitis 30:12–15

    Article  CAS  PubMed  Google Scholar 

  • Jolanki R, Kanerva L, Estlander T, Tarvainen K (1994b) Epoxy dermatitis. In: Nethercott JR (ed) Occupational skin disease, occupational medicine: state of the art reviews, vol 9, part 1. Hanley & Belfus/Medical, Philadelphia, pp 97–112

    Google Scholar 

  • Jolanki R, Kanerva L, Estlander T (1995) Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet light-cured paint, and bisphenol A in dental composite resin. Contact Dermatitis 33:94–99

    Article  CAS  PubMed  Google Scholar 

  • Jolanki R, Kanerva L, Estlander T (1996a) Allergic patch test reactions to diglycidyl ether of bisphenol A in hardened nail base and top coat. Contact Dermatitis 35:246–247

    Article  CAS  PubMed  Google Scholar 

  • Jolanki R, Tarvainen K, Tatar T et al (1996b) Occupational dermatoses from exposure to epoxy resin compounds in a ski factory. Contact Dermatitis 34:390–396

    Article  CAS  PubMed  Google Scholar 

  • Jolanki R, Kanerva L, Estlander T (1997a) Contact urticaria from epoxy resins. In: Amin S, Lahti A, Maibach HI (eds) Contact urticaria syndrome. CRC Press, Boca Raton, pp 143–147

    Google Scholar 

  • Jolanki R, Kanerva L, Estlander T, Tarvainen K (1997b) Skin allergy caused by organic acid anhydrides. In: Amin S, Lahti A, Maibach HI (eds) Contact urticaria syndrome. CRC Press, Boca Raton, pp 217–224

    Google Scholar 

  • Jolanki R, Estlander T, Kanerva L (2001) 182 patients with occupational allergic epoxy contact dermatitis over 22 years. Contact Dermatitis 44:121–123

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Alanko K (1998) Stomatitis and perioral dermatitis caused by epoxy diacrylate in dental composite resins. J Am Acad Dermatol 38:116–120

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Estlander T (1998) Simultaneous active sensitization to multiple chemicals. Contact Dermatitis 38:174–175

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Estlander T, Jolanki R (1989) Allergic contact dermatitis from dental composite resins due to aromatic epoxy acrylates and aliphatic acrylates. Contact Dermatitis 20:201–211

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Jolanki R, Estlander T (1991a) Allergic contact dermatitis from epoxy resin hardeners. Am J. Contact Dermatitis 2:88–97

    Google Scholar 

  • Kanerva L, Jolanki R, Estlander T (1991b) Allergic contact dermatitis from non-diglycidyl ether of bisphenol A epoxy resins. Contact Dermatitis 24:293–300

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Jolanki R, Tupasela O et al (1991c) Immediate and delayed allergy from epoxy resins based on diglycidyl ether of bisphenol A. Scand J Work Environ Health 17:208–215

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Estlander T, Jolanki R (1992) Active sensitization caused by 2-hydroxyethyl methacrylate, 2-hydroxypropyl methacrylate, ethyleneglycol dimethacrylate and N, N-dimethylaminoethyl methacrylate. J Eur Acad Derm Venereol 1:165–169

    Article  Google Scholar 

  • Kanerva L, Tarvainen K, Pinola A et al (1994) A single accidental exposure may result in a chemical burn, primary sensitization and allergic contact sensitization. Contact Dermatitis 31:229–235

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Estlander T, Jolanki R (1996) Occupational allergic contact dermatitis caused by 2.4,6-tris-(dimethylaminomethyl) phenol, and a review of sensitizing epoxy resin hardeners. Int J Dermatol 35:852–856

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Hyry H, Jolanki R et al (1997) Delayed and immediate allergy caused by methylhexahydrophthalic anhydride. Contact Dermatitis 36:34–38

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Jolanki R, Estlander T (1998) Occupational epoxy dermatitis with patch test reactions to multiple hardeners including tetraethylenepentamine. Contact Dermatitis 38:299–301

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Alanko K, Jolanki R, Estlander T (1999a) Airborne allergic contact urticaria from methylhexahydrophthalic anhydride and hexahydrophthalic anhydride. Contact Dermatitis 41:339–341

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Jolanki R, Alanko K, Estlander T (1999b) Patch test reactions with plastic and glue allergens at an occupational dermatology clinic. Acta Derm-Venereol (Stock) 79:296–300

    Article  CAS  Google Scholar 

  • Kanerva L, Jolanki R, Estlander T, Alanko K (2000a) Latent (subclinical) contact dermatitis evolving into occupational allergic contact dermatitis from extremely small amounts of epoxy resin. Contact Dermatitis 43:47–49

    CAS  PubMed  Google Scholar 

  • Kanerva L, Jolanki R, Estlander T, Henriks-Eckerman M, Tuomi M, Tarvainen K (2000b) Airborne occupational allergic contact dermatitis from triglycidyl-p-aminophenol and tetraglycidyl-4,4′-methylene dianiline in preimpregnated epoxy products in the aircraft industry. Dermatology 201:29–33

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Estlander T, Jolanki R, Alanko K (2000c) Occupational allergic contact dermatitis from 2,2-bis[4-(2-hydroxy-3-acryloxypropoxy) phenyl] propane (epoxy diacrylate) in ultraviolet-cured inks. Contact Dermatitis 43:56–59

    CAS  PubMed  Google Scholar 

  • Kanerva L, Estlander T, Keskinen H, Jolanki R (2000d) Occupational allergic airborne contact dermatitis and delayed bronchial asthma from epoxy resin revealed by bronchila provocation test. Eur J Dermatol 10:475–477

    CAS  PubMed  Google Scholar 

  • Kanerva L, Pelttari M, Jolanki R et al (2002) Occupational contact urticaria from diglycidyl ether of bisphenol A resin. Allergy 57:1205–1207

    Article  CAS  PubMed  Google Scholar 

  • Kanerva L, Zwanenburg R (2000) Allergic contact reactions to poly(oxy-1,2-ethanediyl) alpha,alpha'-[(1-methylethylidene)di-4, 1-phenylene]bis[omega-[(2-methyl-1-oxo-2-propenyl)oxy](BIS-EMA). Contact Dermatitis 43:115–117

    Google Scholar 

  • Karlberg A-T, Gafvert E (1996) Isolated colophony allergens as screening substance for contact allergy. Contact Dermatitis 35:201–207

    Article  CAS  PubMed  Google Scholar 

  • Kirkup ME, Murphy J, Beck MH, Sansom JE (2001) Occupational sensitization to 1,2-diaminocyclohexane. Contact Dermatitis 45:121–122

    Article  CAS  PubMed  Google Scholar 

  • Koch P (2002) Occupational allergic contact dermatitis from epoxy resin systems and possibly acetone in a shoemaker. Contact Dermatitis 46:362–363

    Article  PubMed  Google Scholar 

  • Koch P (2003) Allergic contact stomatitis from BIS-GMA and epoxy resins in dental bonding agents. Contact Dermatitis 49:104–105

    Article  PubMed  Google Scholar 

  • Krajewska D, Rudzki E (1976) Sensitivity to epoxy resins and triethylenetetramine. Contact Dermatitis 2:135–138

    Article  CAS  PubMed  Google Scholar 

  • Kumar A, Freeman S (1999) Leukoderma following occupational allergic contact dermatitis. Contact Dermatitis 41:94–98

    Article  CAS  PubMed  Google Scholar 

  • Kwok T, Rosen CF, Storrs FJ et al (2013) Persistent photosensitivity after allergic contact dermatitis to epoxy resin. Dermatitis 24:124–130

    Article  CAS  PubMed  Google Scholar 

  • Lachapelle JM, Tennstedt D, Dumont Fruytier M (1978) Occupational allergic contact dermatitis to isophorone diamine (IPD) used as an epoxy resin hardener. Contact Dermatitis 4:109–112

    Article  CAS  PubMed  Google Scholar 

  • Lea WA, Block WD, Cornish HH (1958) The irritating and sensitizing capacity of epoxy resins. Arch Dermatol 78:304–308

    Article  Google Scholar 

  • Lee H, Neville K (1967) Handbook of epoxy resins. McGraw-Hill, New York

    Google Scholar 

  • Lee HN, Pokorny CD, Law S et al (2002) Cross-reactivity among epoxy acrylates and bisphenol F epoxy resins in patients with bisphenol A epoxy resin sensitivity. Am J Contact Dermat 13:108–115

    PubMed  Google Scholar 

  • Lichter M, Drury D, Remlinger K (1992) Lichenoid dermatitis caused by epoxy resin. Contact Dermatitis 26:275

    Article  CAS  PubMed  Google Scholar 

  • Liu YQ, Zhao S, Zhuang LH, Fan WX (1997) Patch test reactions to the Chinese standard screening allergens in 1,135 patients investigated for allergic contact dermatitis. Am J Contact Dermat 8:141–143

    CAS  PubMed  Google Scholar 

  • Lolatgis HA, Nixon R (2015) Allergic contact dermatitis following epoxy resin exposure to a paint in a recreational setting. Australas J Dermatol 56:312–313

    Article  PubMed  Google Scholar 

  • Lovell CR, Rycroft RJG, Matood J (1984) Isolated Cardura EIO sensitivity in an epoxy resin chemical process. Contact Dermatitis 11:190–191

    Article  CAS  PubMed  Google Scholar 

  • Lushniak B (2004) Occupational contact dermatitis. Dermatol Ther 17:272–277

    Article  PubMed  Google Scholar 

  • Lyon CC, O’Driscoll I, Erikstam U et al (1998) Bowlers’ grip. Contact Dermatitis 38:223

    Article  CAS  PubMed  Google Scholar 

  • Maguire HC (1988) Experimental photoallergic contact dermatitis to bisphenol A. Acta Derm Venerol 68:408–412

    CAS  PubMed  Google Scholar 

  • Maibach HI, Mathias CT (2001) Allergic contact dermatitis from cycloaliphatic epoxide in jet aviation hydraulic fluid. Contact Dermatitis 45:56

    Article  CAS  PubMed  Google Scholar 

  • Majasuo S, Liippo J, Lammintausta K (2012) Non-occupational contact sensitization to epoxy resin of bisphenol A among general dermatology patients. Contact Dermatitis 66:148–153

    Article  CAS  PubMed  Google Scholar 

  • Malanin G, Kalimo K (1985) Facial dermatitis from epoxy resin in a helmet. Contact Dermatits 12:221

    Article  CAS  Google Scholar 

  • Malten K, Zielhuis R (1964) Polyester resins. Industrial toxicology and dermatology in the production and processing of plastics. Elsevier, Amterdam, pp 71–84

    Google Scholar 

  • Mann RI, Stewart E, Peachey RDG (1983) Sensitivity to urostomy pouch plastic. Contact Dermatitis 9:80–81

    Article  CAS  PubMed  Google Scholar 

  • Marks JG, Belsito DV, DeLeo VA et al (1995) North American contact dermatitis group standard tray patch test results (1992 to 1994). Am J Contact Dermat 6:160–165

    Article  Google Scholar 

  • Mathias CGT (1987) Allergic contact dermatitis from a nonbisphenol A epoxy in a graphite fiber reinforced epoxy laminate. J Occup Med 29:754–755

    CAS  PubMed  Google Scholar 

  • Matura M, Poesen N, de Moor A et al (1995) Glycidyl methacrylate and ethoxyethyl acrylate: new allergens in emulsions used to impregnate paper and textile materials. Contact Dermatitis 33:123–134

    Article  CAS  PubMed  Google Scholar 

  • McClain DC, Storrs FJ (1992) Protective effect of both a barrier cream and a polyethylene lamintate glove against epoxy resin, glyceryl monothioglycolate, frullania, and tancy. Am J Contact Dermat 3:201–205

    Google Scholar 

  • Menschik H (1955) Gesundheitliche Gefahren bei der Herstellung von Phthalsäureanhydrid. Arch Gewerbepathol Gewerbehyg 183:454–475

    Google Scholar 

  • Miyamoto T, Okumura M (1998) Occupational contact urticaria due to epoxy resin. Environ Dermatol 5:53–57

    Google Scholar 

  • Morris AD, Ratcliffe J, Dalziel KL, English JSC (1998) Allergic contact dermatitis from epoxy propane. Contact Dermatitis 38:57

    Article  CAS  PubMed  Google Scholar 

  • Mose AP, Lundov MD, Zachariae C, Menné T, Veien NK, Laurberg G, Kaaber K, Avnstorp C, Andersen KE, Paulsen E, Mørtz CG, Sommerlund M, Danielsen A, Thormann J, Kristensen O, Kristensen B, Andersen BL, Vissing S, Nielsen NH, Johansen JD (2012) Occupational contact dermatitis in painters: an analysis of patch test data from the Danish contact dermatitis group. Contact Dermatitis 67:293–297

    Article  CAS  PubMed  Google Scholar 

  • Munro CS, Lawrence CM (1992) Occupational contact dermatitis from triglycidyl isocyanurate in a powder paint factory. Contact Dermatitis 26:59

    Article  CAS  PubMed  Google Scholar 

  • Muskopf JW, McCollister SB (1987) Epoxy resins. In: Gerhartz W, Yamamoto YS, Kaudy L, Rounsaville JF, Schulx G (eds) Ullmann’s encyclopedia of industrial chemistry, 5th completely revised edition, vol A9. VCH Verlagsgesellschaft, Weinheim, pp 547–563

    Google Scholar 

  • Nethercott JR, Holness DI, Adams RM et al (1994) Multivariate analysis of the effect of selected factors on the elicitation of patch test response to 28 common environmental contactants in North America. Am J Contact Dermatol 5:13–18

    Article  Google Scholar 

  • Nielsen J, Welinder H, Horstmann V, Skerfving S (1992) Allergy to methyltetrahydrophthalic anhydride in epoxy resin workers. Br J Ind Med 49:769–775

    CAS  PubMed  PubMed Central  Google Scholar 

  • Niinimäki A, Rosberg J, Saari S (1983) Traces of epoxy resin in acrylic dental materials. Contact Dermatitis 9:532

    Article  PubMed  Google Scholar 

  • Niklasson IB, Broo K, Jonsson C et al (2009) Reduced sensitizing capacity of epoxy resin systems: a structure-activity realationship study. Chem Res Toxicol 22:1787–1794

    Article  CAS  PubMed  Google Scholar 

  • Nishioka K, Ogasawara M, Asagami C (1988) Occupational contact allergy to triglycidyl isocyanurate (TGIC, TepicR). Contact Dermatitis 19:379–380

    Article  CAS  PubMed  Google Scholar 

  • Nixon RL (1997) Material safety data sheets and contact dermatitis: a misleading case. Aust J Dermatol 38:165

    Article  CAS  Google Scholar 

  • Nixon RL, Frowen K (1991) Allergic contact dermatitis caused by epoxy resins. J Occup Health Safety-Aust NZ 7:417–424

    Google Scholar 

  • O’Boyle NM, Delaine T, Luthman K et al (2012) Analogues of the epoxy resin monomer diglycidyl ether of bisphenol F: effects on contact allergenic potency and cytotoxicity. Chem Res Toxicol 25:2469–2478

    Article  PubMed  CAS  Google Scholar 

  • O’Boyle NM, Niklasson IB, Tehrani-Bagha AR et al (2014) Epoxy resin monomers with reduced skin sensitizing potency. Chem Res Toxicol 27:1002–1010

    Article  PubMed  CAS  Google Scholar 

  • Özkaya E (2012) Neighborial allergy: a hidden cause of nonoccupational airborne contact dermatitis in a housewife from epoxy resin. Dermatitis 23:124–125

    Article  PubMed  Google Scholar 

  • Peltonen K (1986) Thermal degradation of epoxy powder paints. Doctoral dissertation, University of Kuipo, Kuopio

    Google Scholar 

  • Pesonen M, Suuronen K, Jolanki R, Aalto-Korte K, Kuuliala O, Henriks-Eckerman ML, Valtanen I, Alanko K (2015) Occupational contact dermatitis caused by aniline epoxy resins in the aircraft industry. Contact Dermatitis 73:113–118

    Article  CAS  PubMed  Google Scholar 

  • Pesonen M, Kuuliala O, Suomela S, Aalto-Korte K (2016) Occupational contact dermatitis caused by 1,3-benzenedimethanamine, N-(2-phenylethyl) derivatives in hardeners for epoxy paints and coatings. Contact Dermatitis 75:358–362

    Article  CAS  PubMed  Google Scholar 

  • Pontén A, Bruze M (2001) Contact allergy to epoxy resin based on diglycidyl ether of bisphenol F. Contact Dermatitis 44:98–99

    Article  PubMed  Google Scholar 

  • Pontén A, Zimerson E, Sörensen Ö, Bruze M (2002) Sensitizing capacity and cross-reaction pattern of the isomers of diglycidyl ether of bisphenol F in the guinea pig. Contact Dermatitis 47:293–298

    Article  PubMed  Google Scholar 

  • Pontén A, Carstensen O, Rasmussen K et al (2004a) Epoxy-based production of wind turbine rotor blades: occupational dernatoses. Contact Dermatitis 50:329–338

    Article  PubMed  Google Scholar 

  • Pontén A, Bjork J, Carstensen O et al (2004b) Associations between contact allergy to epoxy resin and fragrance mix. Acta Derm Venereol (Stockh) 84:151–152

    Article  CAS  Google Scholar 

  • Pontén A, Zimerson E, Bruze M (2004c) Contact allergy to the isomers of diglycidyl ether of bisphenol F. Acta Derm Venereol 84:12–17

    PubMed  Google Scholar 

  • Pontén A, Zimerson E, Bruze M (2004d) Sensitizing capacity and cross-reactivity of phenyl glycidyl ether. Contact Dermatitis 50:166

    Article  Google Scholar 

  • Pontén A, Zimerson E, Bruze M (2008) Can simultaneous contact allergies to phenyl glycidyl ethers and epoxy resins of the bisphenol A/F-types be explained by contamination of the epoxy resins? Contact Dermatitis 59:273–279

    Article  PubMed  Google Scholar 

  • Pontén A, Zimerson E, Bruze M (2009) Sensitizing capacity and cross-reactivity of phenyl glycidyl ether studied in the guinea-pig maximization test. Contact Dermatitis 60:79–84

    Article  PubMed  Google Scholar 

  • Potter WG (1975) Uses of epoxy resins. Newnes·Butterworths, London

    Google Scholar 

  • Prodi A, Rui F, Belloni Fortina A et al (2015) Occupational sensitization to epoxy resins in northeastern Italy (1996-2010). Int J Occup Environ Health 21:82–87

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rebandel P, Rudzki E (1990) Dermatitis caused by epichlorohydrin. Oxprenolol hydrochloride and propranolol hydrochloride. Contact Dermatitis 23:199–200

    Article  CAS  PubMed  Google Scholar 

  • Requena L, Vazquez C, Requena C et al (1986) Epoxy dermatitis of an amputation stump. Contact Dermatitis 14:320

    Article  CAS  PubMed  Google Scholar 

  • Rietschel RL, Fowler JF Jr (2008) Fisher’s contact dermatitis, 6th edn. McGraw-Hill, New York

    Google Scholar 

  • Rietschel RL, Mathias CGT, Fowler JF Jr et al (2002) Relationship of occupation to contact dermatitis: evaluation in patients tested from 1998 to 2000. Am J Contact Dermat 13:170–176

    Article  PubMed  Google Scholar 

  • Roed-Petersen J (1989) A new glove material protective against epoxy and acrylate monomer. In: Lachapelle JM, Frosch PJ, Dooms-Goossens A (eds) Current topics in contact dermatitis. Springer, Berlin/Heidelberg/New York, pp 603–606

    Chapter  Google Scholar 

  • Rømyhr O, Nyfors A, Leira HL, Smedbold HT (2006) Allergic contact dermatitis caused by epoxy resin systems in industrial painters. Contact Dermatitis 55:167–172

    Article  PubMed  Google Scholar 

  • Rosen RH, Freeman S (1993) Prognosis of occupational contact dermatitis in New South Wales, Australia. Contact Dermatitis 29:88–93

    Article  CAS  PubMed  Google Scholar 

  • Rudzki E, Krajewska D (1976) Cross-reactivity between ethylenediamine, diethylenetriamine and triethylenetetramine. Contact Dermatitis 2:311–313

    Article  CAS  PubMed  Google Scholar 

  • Rudzki E, Rebandel P (1990) Dermatitis from methyl 2,3 epoxy-3-(4-methoxyphenyl)propionate. Contact Dermatitis 23:382

    Article  CAS  PubMed  Google Scholar 

  • Rycroft RJG (1980) Atypical psoriasis following epoxy resin sensitization. J Soc Occup Med 30:132–134

    Article  CAS  PubMed  Google Scholar 

  • Sajjachareonpong P, Cahill J, Saunders H et al (2004) Persistent post-occupational dermatitis. Contact Dermatitis 51:278–283

    Article  PubMed  Google Scholar 

  • Sakata S, Cahill J, Barton D, Nixon R (2005) Occupational allergic contact dermatitis to bisphenol F epoxy resin. Australas J Dermatol 46:90–92

    Article  PubMed  Google Scholar 

  • Sasseville D (1998) Contact urticaria from epoxy resin and reactive diluents. Contact Dermatitis 38:57–58

    Article  CAS  PubMed  Google Scholar 

  • Sasseville D, Hakim M, Muhn C (2002) Bus pass dermatitis. Am J Contact Dermat 13(3):146–147

    PubMed  Google Scholar 

  • Savonius B, Keskinen H, Tuppurainen M, Kanerva L (1994) Occupational asthma caused by ethanolamines. Allergy 49:877–881

    Article  CAS  PubMed  Google Scholar 

  • Senff H, Kuhlwein A, Hausen BM (1988) Allergisches Kontaktekzem auf Dicyandiamid. Dermatosen 36:99–101

    CAS  Google Scholar 

  • Silvestre JF, Albares MP, Escutia B et al (2004) Contact vitiligo appearing after allergic contact dermatitis in an epoxy resin system. Contact Dermatitis 49:113–114

    Article  Google Scholar 

  • Skoet R, Tollund C, Bloch-Thomsen PE (2003) Epoxy contact dermatitis due to pacemaker compounds. Cardiology 99:112

    Article  PubMed  Google Scholar 

  • Sommer S, Wilkinson SM, Wilson CL (1997) Airborne contact dermatitis caused by microscopy immersion fluid containing epoxy resin. Contact Dermatitis 39:141–142

    Article  Google Scholar 

  • Spee T, Van Duivenbooden C, Terwoert J (2006) Epoxy resins in the construction industry. Ann N Y Acad Sci (United States) 1076:429–438

    Article  Google Scholar 

  • Spee T, Timmerman JG, Rühl R, Kersting K, Heederik DJJ (2016) Determinants of epoxy allergy in the construction industry: a case-control study. Contact Dermatitis 74:259–266

    Article  CAS  PubMed  Google Scholar 

  • Speight EL, Beck MH, Lawrence CM (1993) Occupational allergic contact dermatitis due to 3-dimethylaminopropylamine. Contact Dermatitis 28:49–50

    Article  CAS  PubMed  Google Scholar 

  • Srinivas CR, Devadiga R, Aroor AR (1989) Footwear dermatitis due to bisphenol A. Contact Dermatitis 20:150–151

    Article  CAS  PubMed  Google Scholar 

  • Steinkraus V, Hausen BM (1994) Contact allergy to propylene oxide. Contact Dermatitis 31:120

    Article  CAS  PubMed  Google Scholar 

  • Stutz N, Hertl M, Löffler H (2008) Anaphylaxis caused by contact urticaria because of epoxy resins: an extraordinary emergency. Contact Dermatitis 58:307–309

    Article  CAS  PubMed  Google Scholar 

  • Suhonen R (1983) Epoxy-dermatitis in a ski-stick factory. Contact Dermatitis 9:131–133

    Article  CAS  PubMed  Google Scholar 

  • Tarvainen K, Iolanki R, Estlander T et al (1995a) Immunologic contact urticaria due to airborne methylhexahydrophthalic and methyltetrahydrophthalic anhydride. Contact Dermatitis 32:204–209

    Article  CAS  PubMed  Google Scholar 

  • Tarvainen K, Kanerva L, Jolanki R, Estlander T (1995b) Occupational dermatoses from the manufacture of plastic composite products. Am J Contact Dermatoses 6:95–104

    Article  Google Scholar 

  • Taylor JS, Bergfeld WF, Guin JD (1983) Contact dermatitis to knee patch adhesive in boy’s jeans: a nonoccupational cause of epoxy resin sensitivity. Cleveland Clin Q 50:123–127

    Article  CAS  Google Scholar 

  • Thorgeirsson A (1978a) Sensitization capacity of epoxy reactive diluents in the guinea pig. Acta Derm Venerol 58:329–331

    CAS  PubMed  Google Scholar 

  • Thorgeirsson A (1978b) Sensitization capacity of epoxy resin hardeners in the guinea pig. Acta Derm Venerol 58:332–336

    CAS  Google Scholar 

  • Thorgeirsson A, Fregert S (1977) Allergenicity of epoxy resins in the guinea pig. Acta Derm Venerol 57:253–256

    CAS  PubMed  Google Scholar 

  • Thorgeirsson A, Fregert S, Ramnäs O (1978) Sensitization capacity of epoxy resin oligomers in the guinea pig. Acta Derm Venerol 58:17–21

    CAS  PubMed  Google Scholar 

  • Toffoletto F, Cortona G, Feltrin G et al (1994) Occupational contact dermatitis from aminefunctional methoxysilane in continuous-glass-filament production. Contact Dermatitis 31:320–321

    Article  CAS  PubMed  Google Scholar 

  • Toome BK (1989) Allergic contact dermatitis to a nasal cannula. Arch Dermatol 125:571

    Article  CAS  PubMed  Google Scholar 

  • Tosti A, Guerra L, Toni F (1988) Occupational airborne contact dermatitis due to epoxy resin. Contact Dermatitis 19:220–222

    Article  CAS  PubMed  Google Scholar 

  • Tosti A, Guerra L, Bardazzi F (1992) Occupational contact dermatitis from exposure to epoxy resins and acrylates. Clin Dermatol 10:133–140

    Article  CAS  PubMed  Google Scholar 

  • Uter W, Amario-Hita JC, Balato A, Ballmer-Weber B, Bauer A, Belloni Fortina A, Bircher A, Chowdhury MMU, Cooper SM, Dugonik A, Gallo R, Giménez-Arnau A, Johansen JD, John SM, Kieć-Świerczyńska M, Kmecl T, Kręcisz B, Larese Filon F, Mahler V, Pesonen M, Rustemeyer T, Sadowska-Przytocka A, Sánchez-Perez J, Schliemann S, Schuttelaar ML, Simon D, Spiewak R, Valiukeviciene S, Weisshaar E, White IR, Wilkinson SM (2017) European surveillance system on contact allergies (ESSCA): results with the European baseline series, 2013/14. J Eur Acad Dermatol Venereol. https://doi.org/10.1111/jdv.14423. [Epub ahead of print]

  • Van Joost T (1988) Occupational sensitization to epichlorohydrin and epoxy resin. Contact Dermatitis 19:278–280

    Article  PubMed  Google Scholar 

  • Van Joost T, Roesyanto ID, Satyawan I (1990) Occupational sensitization to epichlorohydrin (ECH) and bisphenol-A during the manufacture of epoxy resin. Contact Dermatitis 22:125–126

    Article  PubMed  Google Scholar 

  • Van Putten PB, Coenraads PJ, Nater JP (1984) Hand dermatoses and contact allergic reactions in construction workers exposed to epoxy resins. Contact Dermatitis 10:146–150

    Article  PubMed  Google Scholar 

  • Vanherle G, Smith DC (eds) (1985) Posterior composite resin dental restorative materials. Minnesota Mining Mfg, St. Paul

    Google Scholar 

  • Veien NK, Hattel T, Laurberg G (1992) Patch test results from a private dermatologic practice for two periods of 5 years with a 10-year interval. Am J Contact Dermatol 3:189–192

    Article  Google Scholar 

  • Warshaw EM, Nelsen DD, Sasseville D, Belsito DV, Maibach HI, Zug KA, Fowler JF Jr, Taylor JS, DeLeo VA, Marks JG Jr, Storrs FJ, Mathias CG, Pratt MD, Rietschel RL (2010) Positivity ratio and reaction index: patch-test quality-control metrics applied to the north american contact dermatitis group database. Dermatitis 21:91–97

    CAS  PubMed  Google Scholar 

  • Wenk K, Ehrlich A (2010) Allergic contact dermatitis from epoxy resin in solder mask coating in an individual working with printed circuit boards. Dermatitis 21:288–291

    PubMed  Google Scholar 

  • Word AP, Nezafati KA, Cruz PD Jr (2011) Ear dermatitis + epoxy reactivity = hearing aid allergy? Dermatitis 22:350–354

    PubMed  Google Scholar 

  • Wurpts G, Merk HF (2010) Allergie gegen Autositz. Hautarzt 61:933–934

    Article  CAS  PubMed  Google Scholar 

  • Woyton A, Wasik F, Bliζanowska A (1974) An uncommon anaphylactic and eczematous reaction after contact with epoxide resins (in Polish). Przegl Dermatol 61:303–308

    CAS  PubMed  Google Scholar 

  • Yokota K, Johyama Y, Miyaue H, Matsumoto N, Yamaguchi K (2001) Occupational contact urticaria caused by airborne methylhexahydrophthalic anhydride. Ind Health 39:347–352

    Article  CAS  PubMed  Google Scholar 

  • Yokota K, Michitsuji H (2004) Occupational allergic contact dermatitis from 1,6-bis (2,3-epoxypropoxy) naphthalene in a one-component epoxy coating. Contact Dermatitis 51:154–155

    Article  PubMed  Google Scholar 

  • Yung A, Wilkinson SM (2003) Allergic contact dermatitis from the epoxy resin plasticizer diglycidyl ether of propylene glycol. Contact Dermatitis 49(2):109–110

    Article  CAS  PubMed  Google Scholar 

  • Zug KA, Warshaw EM, Fowler JF et al (2009) Patch-test results of the north American contact dermatitis group 2005–2006. Dermatitis 20:149–160

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Occupational Dermatology Research and Education Centre, Skin and Cancer Foundation, Melbourne, VIC, Australia

    Claire Higgins, Jennifer Cahill & Rosemary Nixon

  2. Control of Hypersensitivity Diseases, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland

    Riitta Jolanki

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  1. Claire Higgins
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  2. Jennifer Cahill
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  4. Rosemary Nixon
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Correspondence to Rosemary Nixon .

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Editors and Affiliations

  1. Department of Dermatology, University of Osnabrück, Osnabrück, Niedersachsen, Germany

    Swen Malte John

  2. Department of Dermato-allergology, Gentofte Hospital, Hellerup, Denmark

    Jeanne Duus Johansen

  3. Dept. of Dermatology and Allergology, VU University Medical Centre, Amsterdam, The Netherlands

    Thomas Rustemeyer

  4. Dept. of Dermatology and Allergology, Friedrich Schiller University, Jena, Thüringen, Germany

    Peter Elsner

  5. Department of Dermatology, University of California San Francisco, San Francisco, California, USA

    Howard I. Maibach

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Higgins, C., Cahill, J., Jolanki, R., Nixon, R. (2018). Epoxy Resins. In: John, S., Johansen, J., Rustemeyer, T., Elsner, P., Maibach, H. (eds) Kanerva’s Occupational Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-40221-5_51-2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-40221-5

  • Online ISBN: 978-3-319-40221-5

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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