Multisystem Atrophy (MSA)
MSA can cause combinations of Parkinsonism, autonomic, pyramidal and cerebellar symptoms. MSA-A is now the term used for Shy-Drager syndrome, MSA-C if cerebellar symptoms predominate and MSA-P if Parkinsonian features predominate. The aetiology is uncertain although recently it has been attributed to a human prion composed of the alpha-synuclein protein. This chapter gives a concise account of the demographic, clinical characteristics and management of the disease.
KeywordsMultiple system antrophy Parkinsonism Shy-Drager syndrome Autonomic dysfunction Antecolis Myotonic jerks
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