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Adnexal Tumors of the Orbit and Ocular Adnexa, Cytological Findings

  • Reference work entry
  • First Online:
Cytopathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 132 Accesses

Definition

Adnexal tumors arise from skin adnexa, Meibomian and Zeis glands. Much of these tumors differentiate along one adnexal line, forming distinct morphological and phenotypical types. Differentiation along two lines in the same tumor, either benign or malignant, may occur. Most of the tumors are benign, but apocrine, mucinous, and signet adenocarcinoma and Meibomian or Zeis carcinoma may occur.

Clinical Features

  • Incidence

    Infrequent, Meibomian and Zeis gland tumors more frequent in Asian countries.

  • Age

    Middle-old age.

  • Sex

    No gender predilection.

  • Site

    Adnexal tumors – eyelids skin, Meibomian: the eyelids rim inside the tarsal plate. Zeis: the margin of the eyelids.

  • Treatment

    Surgery, chemotherapy.

  • Outcome

    Favorable for benign tumors. Variable for malignant adnexal tumors. Unfavorable in more than 25% of Meibomian carcinoma.

Description

Eyelid hidradenoma and eccrine poroma diagnosed by FNA have been reported. Hidradenoma has been described as a cystic tumor showing an amorphous...

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References and Further Reading

  • Agarwal, S., Agarwal, K., Kathuria, P., Jain, M., Chauhan, D. S., & Prakash, O. (2006). Cytomorphological features of nodular hidradenoma highlighting eccrine differentiation: A case report. Indian Journal of Pathology and Microbiology, 49, 411–413.

    PubMed  Google Scholar 

  • Agrawal, P., Dey, P., & Lal, A. (2013). Fine-needle aspiration cytology of orbital and eyelid lesions. Diagnostic Cytopathology, 41, 1000–1011.

    Article  PubMed  Google Scholar 

  • Glasgow, B. J., & Foos, R. Y. (1993). Ocular cytopathology. Boston: Butterworth-Heinemann ED.

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  • Koss, L. G. (2006). The eyelids, orbit and eye. In Koss’ diagnostic cytology (5th ed., pp. 1508–1522). Philadelphia: Lippincott Williams & Wilkins.

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  • Rosenthal, D. L., Mandell, D. B., & Glasgow, B. J. (1991). Eye. In M. Bibbo (Ed.), Comprehensive cytopathology (pp. 484–501). Philadelphia: WB Saunders.

    Google Scholar 

  • Zeppa, P., & Palombini, L. (2010). The eye, orbit and ocular adnexa. In W. Grey & G. Kocjan (Eds.), Diagnostic cytopathology (3rd ed., pp. 911–923). New York: Churchill Livingstone.

    Google Scholar 

  • Zeppa, P., Tranfa, F., Errico, M. E., Troncone, G., Fulciniti, F., Vetrani, A., Bonavolontà, G., & Palombini, L. (1997). Fine needle aspiration (FNA) biopsy of orbital masses: A critical review of 51 cases. Cytopathology, 8, 366–372.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Medicine and Surgery, Department of Pathology, University of Salerno (IT), Salerno, Italy

    Pio Zeppa

  2. Department of Biomedical Advanced Sciences, University of Naples “Federico II”, Naples, Italy

    Elena Vigliar

Authors
  1. Pio Zeppa
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  2. Elena Vigliar
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Corresponding author

Correspondence to Pio Zeppa .

Editor information

Editors and Affiliations

  1. Laboratoire national de santé, Luxembourg City, Luxembourg

    Fernando Schmitt

  2. Medical Faculty of Porto University and IPATIMUP, Porto, Portugal

    Fernando Schmitt

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Zeppa, P., Vigliar, E. (2017). Adnexal Tumors of the Orbit and Ocular Adnexa, Cytological Findings. In: Schmitt, F. (eds) Cytopathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-33286-4_2814

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  • DOI: https://doi.org/10.1007/978-3-319-33286-4_2814

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-33285-7

  • Online ISBN: 978-3-319-33286-4

  • eBook Packages: MedicineReference Module Medicine

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