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Pediatric (Nontuberculous) Spinal Infections

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Textbook of Pediatric Neurosurgery

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Abstract

Spinal infections were first found in Egyptian mummies dating back to 3400 BC (Taylor et al. 2007). However, in spite of being some of the oldest infections known to mankind, infectious diseases of the spine in the pediatric population are uncommon entities and have varied presentations. In contrast to adult spinal infections, our current knowledge of pediatric spinal infections is predominantly derived from case reports and small case series. Pediatric spinal infections can be classified based on location into epidural abscess, spondylodiscitis, and intradural spinal infections (intramedullary and extramedullary). Alternatively, they can be classified based on etiology into bacterial (pyogenic), viral, fungal, and parasitic infection, and postoperative spinal infections.

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References

  • Auletta JJ, John CC (2001) Spinal epidural abscesses in children: a 15-year experience and review of the literature. Clin Infect Dis 32:9–16

    Article  CAS  PubMed  Google Scholar 

  • Bartels RH, de Jong TR, Grotenhuis JA (1992) Spinal subdural abscess. Case report. J Neurosurg 76:307–311

    Article  CAS  PubMed  Google Scholar 

  • Candon E, Frerebeau P (1994) Bacterial abscesses of the spinal cord. Review of the literature (73 cases). Rev Neurol (Paris) 150:370–376

    CAS  Google Scholar 

  • Chan CT, Gold WL (1998) Intramedullary abscess of the spinal cord in the antibiotic era: Clinical features, microbial etiologies, trends in pathogenesis, and outcomes. Clin Infect Dis 27:619–626

    Article  CAS  PubMed  Google Scholar 

  • Chen WH, Jiang LS, Dai LY (2007) Surgical treatment of pyogenic vertebral osteomyelitis with spinal instrumentation. Eur Spine J 16:1307–1316

    Article  PubMed  Google Scholar 

  • Chen WC, Wang JL, Wang JT et al (2008) Spinal epidural abscess due to Staphylococcus aureus: clinical manifestations and outcomes. J Microbiol Immunol Infect 41:215–221

    PubMed  Google Scholar 

  • Citow J, Ammirati M (1994) Intramedullary tuberculoma of the spinal cord: case report. Neurosurgery 35:327–330

    Article  CAS  PubMed  Google Scholar 

  • Curry WT, Hoh BL, Amin-Hanjani S et al (2005) Spinal epidural abscess: clinical presentation, management, and outcome. Surg Neurol 63:364–371

    Article  PubMed  Google Scholar 

  • De Moraes Barros Fucs PM, Meves R, Yamada HH (2012) Spinal infections in children: a review. Int Orthop 36:387–395

    Article  Google Scholar 

  • Devi BI, Chandra S, Mongia S et al (2002) Spinal intramedullary tuberculoma and abscess: A rare cause of paraparesis. Neurol India 50:494–496

    PubMed  Google Scholar 

  • Doganay S, Kantarci M (2009) Role of conventional and diffusion-weighted magnetic resonance imaging of spinal treatment protocol for hydatid disease. J Spinal Cord Med 32:574–577

    Article  PubMed  PubMed Central  Google Scholar 

  • Dörflinger-Hejlek E, Kirsch EC, Reiter H et al (2010) Diffusion-weighted MR imaging of intramedullary spinal cord abscess. AJNR Am J Neuroradiol 31:1651–1652

    Article  PubMed  Google Scholar 

  • Dormans JP, Moroz L (2007) Infection and tumors of the spine in children. J Bone Joint Surg Am 89:79–97

    PubMed  Google Scholar 

  • Enberg RN, Kaplan RJ (1974) Spinal epidural abscess in children. Early diagnosis and immediate surgical drainage is essential to forestall paralysis. Clin Pediatr 13:247–248

    Article  CAS  Google Scholar 

  • Fernandez M, Carrol CL, Baker CJ (2000) Discitis and vertebral osteomyelitis in children: an 18-year review. Pediatrics 105:1299–1304

    Article  CAS  PubMed  Google Scholar 

  • Fischer EG, Greene CS Jr, Winston KR (1981) Spinal epidural abscess in children. Neurosurgery 9:257–260

    CAS  PubMed  Google Scholar 

  • Fu TS, Chen LH, Chen WJ (2013) Minimally invasive percutaneous endoscopic discectomy and drainage for infectious spondylodiscitis. Biom J 36:168–174

    Google Scholar 

  • Gouliouris T, Aliyu SH, Brown NM (2010) Spondylodiscitis: update on diagnosis and management. J Antimicrob Chemother 65(Suppl 3):iii11–iii24

    CAS  PubMed  Google Scholar 

  • Hadjipavlou AG, Mader JT, Necessary JT, Muffoletto AJ (2000) Hematogenous pyogenic spinal infections and their surgical management. Spine (Phila Pa 1976) 25:1668–1679

    Article  CAS  Google Scholar 

  • Hogan QH (1996) Epidural anatomy examined by cryomicrotome section. Influence of age, vertebral level, and disease. Reg Anesth 21:395–406

    CAS  PubMed  Google Scholar 

  • Jacobsen FS, Sullivan B (1984) Spinal epidural abscesses in children. Orthopedics 17:1131–1138

    Google Scholar 

  • Kurita N, Sakurai Y, Taniguchi M et al (2009) Intramedullary spinal cord abscess treated with antibiotic therapy. Neurol Med Chir 49:262–268

    Article  Google Scholar 

  • Martin RJ, Yuan HA (1996) Neurosurgical care of spinal epidural, subdural, and intramedullary abscesses and arachnoiditis. Orthop Clin North Am 27:125–136

    CAS  PubMed  Google Scholar 

  • Maurice-Williams RS, Pamphilon D, Coakham HB (1980) Intramedullary abscess – a rare complication of spinal dysraphism. J Neurol Neurosurg Psychiatry 43:1045–1048

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mohindra S, Gupta R, Chhabra R et al (2008) Infected intraparenchymal dermoids: an underestimated entity. J Child Neurol 23:1011–1016

    Article  PubMed  Google Scholar 

  • Morandi X, Mercier P, Fournier H-D et al (1999) Dermal sinus and intramedullary spinal cord abscess. Report of two cases and review of the literature. Childs Nerv Syst 15:202–207

    Article  CAS  PubMed  Google Scholar 

  • Neumayr A, Tamarozzi F, Goblirsch S et al (2013a) Spinal Cystic Echinococcosis – A Systematic Analysis and Review of the Literature: Part 1. Epidemiology and Anatomy. PLoS Negl Trop Dis 7:e2450

    Article  PubMed  PubMed Central  Google Scholar 

  • Neumayr A, Tamarozzi F, Goblirsch S et al (2013b) Spinal cystic echinococcosis--a systematic analysis and review of the literature: part 2. Treatment, follow-up and outcome. PLoS Negl Trop Dis 7:e2458

    Article  PubMed  PubMed Central  Google Scholar 

  • Principi N, Esposito S (2016) Infectious discitis and spondylodiscitis in children. Int J Mol Sci 17:1464

    Article  Google Scholar 

  • Qi B, Ge P, Yang H et al (2011) Spinal Intramedullary Cysticercosis: A Case Report and Literature Review. Int J Med Sci 8:420–423

    Article  PubMed  PubMed Central  Google Scholar 

  • Rigamonti D, Liem L, Sampath P et al (1999) Spinal epidural abscess: contemporary trends in etiology, evaluation, and management. Surg Neurol 52:189–196

    Article  CAS  PubMed  Google Scholar 

  • Rubin G, Michowitz SD, Ashkenazi A et al (1993) Spinal epidural abscess in the pediatric age group: case report and review of literature. Pediatr Infect Dis J 12:1007–1011

    Article  CAS  PubMed  Google Scholar 

  • Sandler AL, Thompson D, Goodrich JT et al (2013) Infections of the spinal subdural space in children: a series of 11 contemporary cases and review of all published reports. A multinational collaborative effort. Childs Nerv Syst 29:105–117

    Article  PubMed  Google Scholar 

  • Shah LM, Ross JS (2016) Imaging of Degenerative and Infectious Conditions of the Spine. Neurosurgery 79:315–335

    Article  PubMed  Google Scholar 

  • Sharma MC, Arora R, Deol PS et al (2002) Intramedullary tuberculoma of the spinal cord: a series of ten cases. Clin Neurol Neurosurg 104:279–284

    Article  CAS  PubMed  Google Scholar 

  • Siddiq F, Chowfin A, Tight R (2004) Medical vs surgical management of spinal epidural abscess. Arch Intern Med 164:2409–2412

    Article  PubMed  Google Scholar 

  • Simon JK, Lazareff JA, Diament MJ et al (2003) Intramedullary abscess of the spinal cord in children: a case report and review of the literature. Pediatr Infect Dis J 22:186–192

    PubMed  Google Scholar 

  • Skaf GS, Domloj NT, Fehlings MG et al (2010) Pyogenic spondylodiscitis: an overview. J Infect Public Health 3:5–16

    Article  CAS  PubMed  Google Scholar 

  • Sobottke R, Seifert H, Fätkenheuer G et al (2008) Current diagnosis and treatment of spondylodiscitis. Dtsch Arztebl Int 105:181–187

    PubMed  PubMed Central  Google Scholar 

  • Taylor GM, Murphy E, Hopkins R et al (2007) First report of Mycobacterium bovis DNA in human remains from the Iron Age. Microbiology 153:1243–1249

    Article  CAS  PubMed  Google Scholar 

  • Tovar-Spinoza Z, Bode M (2011) Spinal epidural abscess in a neonate. J Neurosurg Pediatr 7:205–208

    Article  PubMed  Google Scholar 

  • Tufan K, Cekinmez M, Sener L et al (2008) Infected lumbar dermoid cyst presenting with tetraparesis secondary to holocord central lesion. J Child Neurol 23:934–937

    Article  PubMed  Google Scholar 

  • Vadivelu S, Desai SK, Illner A et al (2014) Infected lumbar dermoid cyst mimicking intramedullary spinal cord tumor: Observations and outcomes. J Pediatr Neurosci 9:21–26

    Article  PubMed  PubMed Central  Google Scholar 

  • Vergori A, Cerase A, Migliorini L et al (2015) Pediatric spinal epidural abscess in an immunocompetent host without risk factors: Case report and review of the literature. IDCases 2:109–115

    Article  PubMed  PubMed Central  Google Scholar 

  • Volkan E (2012) Intramedullary spinal cord abscesses in children: a review. J Neurol Sci 28(4):651–661

    Google Scholar 

  • Young A, Tekes A, Huisman TA et al (2015) Spondylodiscitis associated with button battery ingestion:Prompt evaluation with MRI. Neuroradiol J 28:504–507

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Neurosurgery, Bombay Hospital (Institute of Medical Sciences), Mumbai, India

    Chandrashekhar E. Deopujari & Chandan B. Mohanty

  2. Consultant Neurosurgeon, Bombay Hospital, Mumbai, India

    Chandan B. Mohanty

Authors
  1. Chandrashekhar E. Deopujari
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  2. Chandan B. Mohanty
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Corresponding author

Correspondence to Chandrashekhar E. Deopujari .

Editor information

Editors and Affiliations

  1. International Neuroscience Institute, Hannover, Germany

    Concezio Di Rocco

  2. Oakland Medical Center, Oakland, California, USA

    Dachling Pang

  3. University of Toronto Hospital for Sick Children, Toronto, Ontario, Canada

    James T. Rutka

Section Editor information

  1. Davis; and Kaiser Permanente Hospitals of Northern California, University of California, Oakland, United States of America

    Dachling Pang

  2. Seoul National University, Seoul, Republic of Korea

    Kyu-Chang Wang

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Deopujari, C.E., Mohanty, C.B. (2017). Pediatric (Nontuberculous) Spinal Infections. In: Di Rocco, C., Pang, D., Rutka, J. (eds) Textbook of Pediatric Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-31512-6_139-1

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  • DOI: https://doi.org/10.1007/978-3-319-31512-6_139-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31512-6

  • Online ISBN: 978-3-319-31512-6

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