Encyclopedia of Pathology

Living Edition
| Editors: J.H.J.M. van Krieken


Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-28845-1_771-1



Ranula, meaning “frog-like” in Latin, is a clinical variant of a mucocele that presents as a large swelling in the floor of the mouth (Fig. 1). It is a mucous retention phenomenon of the large salivary glands, in contrast with mucoceles, which originate from minor salivary glands. They occur as a result of excretory duct disruption, usually of the sublingual gland and less frequently of the submandibular gland.
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References and Further Reading

  1. Hayashida, A. M., Zerbinatti, D. C. Z., Balducci, I., Cabral, L. A. G., & Almeida, J. D. (2010). Mucus extravasation and retention phenomena: A 24-year study. BMC Oral Health, 10, 15–18.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Kokong, D., Iduh, A., Chukwu, I., Mugu, J., Nuhu, S., & Augustine, S. (2017). Ranula: Current concept of pathophysiologic basis and surgical management options. World Journal of Surgery, 41, 1476–1481.CrossRefPubMedPubMedCentralGoogle Scholar
  3. Patel, M. R., Deal, A. M., & Shockley, W. W. (2009). Oral and plunging ranulas: What is the most effective treatment? Laryngoscope, 119, 1501–1509.CrossRefPubMedPubMedCentralGoogle Scholar
  4. Zhao, Y. F., Jia, Y. L., Chen, X. M., & Zhang, W. F. (2004). Clinical review of 580 ranulas. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 98, 281–287.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of PathologyThe National Cancer Institute, Antoni van Leeuwenhoek HospitalAmsterdamThe Netherlands