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Ranula, meaning “frog-like” in Latin, is a clinical variant of a mucocele that presents as a large swelling in the floor of the mouth (Fig. 1). It is a mucous retention phenomenon of the large salivary glands, in contrast with mucoceles, which originate from minor salivary glands. They occur as a result of excretory duct disruption, usually of the sublingual gland and less frequently of the submandibular gland.
References and Further Reading
Hayashida, A. M., Zerbinatti, D. C. Z., Balducci, I., Cabral, L. A. G., & Almeida, J. D. (2010). Mucus extravasation and retention phenomena: A 24-year study. BMC Oral Health, 10, 15–18.
Kokong, D., Iduh, A., Chukwu, I., Mugu, J., Nuhu, S., & Augustine, S. (2017). Ranula: Current concept of pathophysiologic basis and surgical management options. World Journal of Surgery, 41, 1476–1481.
Patel, M. R., Deal, A. M., & Shockley, W. W. (2009). Oral and plunging ranulas: What is the most effective treatment? Laryngoscope, 119, 1501–1509.
Zhao, Y. F., Jia, Y. L., Chen, X. M., & Zhang, W. F. (2004). Clinical review of 580 ranulas. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 98, 281–287.
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van der Wal, J.E. (2017). Ranula. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_771-1
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DOI: https://doi.org/10.1007/978-3-319-28845-1_771-1
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