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Encyclopedia of Pathology pp 1–2Cite as

Naevus, Unius Lateris

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Ichthyosis hystrix; Linear epidermal nevus; Linear verrucous epidermal nevus

Definition

Nevus unius lateris typically involves the skin of one half of the body with linear, papillary, or verrucous lesions in a unilateral distribution, usually along the axis of a limb or across the trunk. The epidermal nevi are arranged in a whorled fashion in the pattern of Blaschko’s lines. When there is a bilateral widespread distribution of the nevi, the condition is termed ichthyosis hystrix.

Lesions are usually congenital and are frequently associated with sensory disturbances. Oral involvement is rare. The oral lesions are papillary, wartlike proliferations with the same color as the surrounding normal mucosa with a typical linear distribution. They may be associated with hypodontia, morphologic tooth abnormalities, and unerupted teeth (Brown and Gorlin 1960; Haberland-Carrodeguas et al. 2008).

Clinical Features

  • Incidence: Oral involvement is extremely rare. From the first report in...

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References and Further Reading

  • Brown, H. M., & Gorlin, R. J. (1960). Oral mucosal involvement in nevus unius lateris (ichthyosis hystrix). Archives of Dermatology, 81, 509–515.

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  • Haberland-Carrodeguas, C., Allen, C. M., Lovas, J. G. L., Hicks, J., Flaitz, C. M., Carlos, R., & Stal, S. (2008). Review of linear epidermal nevus with oral mucosal involvement – series of five new cases. Oral Diseases, 14, 131–137.

    Article  CAS  PubMed  Google Scholar 

  • Hickman, R. E., Eveson, J. W., & Cawson, R. A. (1988). Nevus unius lateris and intraoral verrucous nevi. Oral Surgery, Oral Medicine, and Oral Pathology, 66, 226–229.

    Article  CAS  PubMed  Google Scholar 

  • Kim, I. S., Choi, S. Y., Park, K. Y., Li, K., Kim, B. J., Seo, S. J., Kim, M. N., & Hong, C. K. (2012). Annals of Dermatology, 24, 480–481.

    Article  PubMed  PubMed Central  Google Scholar 

  • Tesi, D., & Ficarra, G. (2010). Oral linear epidermal nevus: A review of the literature and report of two new cases. Head and Neck Pathology, 4, 139–143.

    Article  PubMed  PubMed Central  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Pathology, Antoni van Leeuwenhoek Hospital, The Netherlands Cancer Institute, Amsterdam, The Netherlands

    Jacqueline E. van der Wal

Authors
  1. Jacqueline E. van der Wal
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Correspondence to Jacqueline E. van der Wal .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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van der Wal, J.E. (2018). Naevus, Unius Lateris. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_746-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_746-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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