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Encyclopedia of Pathology pp 1–2Cite as

Naevus, Oral Epithelial

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Intraoral epidermal nevus; Sublingual keratosis

Definition

An oral epithelial nevus is a symptomless white plaque of the ventral lingual mucosa and floor of mouth, sharply defined, irregularly butterfly shaped with a wrinkled surface. It used to be regarded as a harmless developmental anomaly. As such, it has been described just a few times in the literature, especially in the early 1950s. Pindborg reported in 1972 in a study on floor of the mouth leukoplakia that a similar white lesion as an oral epithelial nevus in the floor of the mouth was not as harmless as an oral epithelial nevus should be (Cardesa and Slootweg 2006; Cooke 1956).

Kramer et al. (1978) suggested it to be a form of leukoplakia with a high risk of malignant transformation and suggested to put it in a separate category and name it sublingual keratosis. Nowadays, it seems that the lesion has returned in the category of Leukoplakia, since no further reports have been found in the literature in recent years...

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References and Further Reading

  • Cardesa, A., & Slootweg, P. J. (2006). Pathology of the head and neck (p. 84). Berlin/Heidelberg: Springer-Verlag.

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  • Cooke, B. E. D. (1956). Leukoplakia buccalis and oral epithelial naevi: A clinical and histological study. The British Journal of Dermatology, 68, 151–174.

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  • Frame, J. W. (1984). Treatment of sublingual keratosis with the CO2 laser. British Dental Journal, 156, 243–246.

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  • Kramer, I. R., El-Labban, N., & Lee, K. W. (1978). The clinical features and risk of malignant transformation in sublingual keratosis. British Dental Journal, 144, 171–180.

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  • Pogrel, M. A. (1979). Sublingual keratosis and malignant transformation. Journal of Oral Pathology, 8, 281–284.

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Author information

Authors and Affiliations

  1. Department of Pathology, Antoni van Leeuwenhoek Hospital, The Netherlands Cancer Institute, Amsterdam, The Netherlands

    Jacqueline E. van der Wal

Authors
  1. Jacqueline E. van der Wal
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Correspondence to Jacqueline E. van der Wal .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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van der Wal, J.E. (2018). Naevus, Oral Epithelial. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_745-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_745-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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