Living reference work entry
Oropharyngeal candidiasis is a common oral disease that may cause oral symptoms (oral burning symptoms, glossodynia, odynophagia, dysphagia, dysgeusia), lead to regional infection, and increase the risk of systemic fungal infection in the compromised host. Candida albicans is a commensal organism found in 34–68% of the normal healthy population in the gastrointestinal and reproductive tracts. Normally, the oral epithelium acts as a physical barrier against Candida infection. In order to colonize the oral cavity/oropharynx, the fungus must adhere to and invade and damage the epithelial cell lining of the oral mucosa without being killed by antimicrobial host factors. Due to several local and systemic factors the local host defense is weakened predisposing to candidiasis (Table 1).
Factors predisposing to oral candidiasis
Wearing of oral appliances...
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